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A-Z
> Cytokine Targets
Closer to the natural conformation in humans due to expressed by HEK293 cells
Various species: Human, Mouse, Rat, Cynomolgus, Rhesus Macaque, Rabbit, Cannie, suitable for species cross experiments
Various labels and tags
Biotinylated cytokines are exclusively produced using the AvitagTM technology: the biotinylation only happens on the lysine residue of Avi tag; no interference with the target protein’s natural binding activities; the protein orientation is uniform when immobilized on an avidin-coated surface
High purity and homogeneity in structure are verified by both SDS-PAGE and SEC-MALS
High bioactivity of binding with receptor or antibody is verified by ELISA/SPR/BLI/cell-based assay. Protocols shared
Strict quality control to guarantee high batch-to-batch consistency (ELISA as QC test)
More comprehensive cytokine products, hot cytokine targets are available
Human IL-2RB&IL-2RG Heterodimer Protein, Fc Tag&Fc Tag (MALS verified) (Cat. No. ILG-H5254) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%. As verified by SEC-MALS, the purity is more than 90% and the molecular weight of this protein is around 140-160 kDa.
Biotinylated Human TGFBR2, Fc,Avitag (Cat. No. TG2-H82F6) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%. As verified by SEC-MALS, the purity is more than 90% and the molecular weight of this protein is around 110-125 kDa.
Biotinylated Human TNF-alpha, His,Avitag (active trimer) (MALS verified) (Cat. No. TNA-H82E3) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%. As verified by SEC-MALS, the purity is more than 90% and the molecular weight of this protein is around 55-70 kDa.
Human GDF-15, Fc Tag (Cat. No. GD5-H5269) on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The purity of the protein is greater than 95%. As verified by SEC-MALS, the purity is more than 90% and the molecular weight of this protein is around 74-100 kDa..
Immobilized Human 4-1BB, Fc Tag (Cat. No. 41B-H5258) at 0.1 μg/mL (100 μL/well) can bind Biotinylated Human 4-1BB Ligand, Fc, Avitag (Cat. No. 41L-H82F9) with a linear range of 0.4-6 ng/mL (QC tested).
Immobilized Cetuximab at 2 μg/mL (100 μL/well) can bind Human EGF R, His Tag (Cat. No. EGR-H5222) with a linear range of 0.006-0.025 μg/mL (QC tested).
Immobilized Human Complement C5, His Tag (Cat. No. CO5-H52Ha) at 2 μg/mL (100 μL/well) can bind Anti-C5a (Human IgG1) with a linear range of 0.2-3 ng/mL (QC tested).
Erbitux (Cetuximab) captured on CM5 chip via anti-human IgG Fc antibodies surface, can bind Human EGF R, His Tag (Cat. No. EGR-H5222) with an affinity constant of 1.3 nM as determined in a SPR assay (Biacore T200).
Loaded Anti-IL23A & IL12B MAb (P40 domain) on Protein A Biosensor, can bind Human IL-12B&IL-12A Heterodimer Protein, His Tag&Flag Tag (Cat. No. IL2-H4210) with an affinity constant of 1.07 nM as determined in BLI assay (ForteBio Octet Red96e).
Loaded Anti-IL23A & IL12B MAb (P40 domain) on Protein A Biosensor, can bind Human IL-23A&IL-12B Heterodimer Protein, His Tag&Tag Free (Cat. No. ILB-H52W5) with an affinity constant of 0.588 nM as determined in BLI assay (ForteBio Octet Red96e).
>>> [Inspiring Target] Therapeutic Potential of Complement in Inflammation, Cancer, and COVID-19
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