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CAR-Targets für Hämatologische Malignome
Verschiedene Spezien, darunter Mensch, Maus, Affe, Kaninchen usw.
Hohe Bioaktivität, bestätigt durch FACS/ELISA/SPR
Star Staining- Alexa Fluor 488/555/647, PE, APC, FITC-Labels sind verfügbar
Einige Produkte sind beim DMF der FDA eingereicht worden, um Ihre IND, NDA und BLA zu unterstützen
The purity of Human CD4, Fc Tag (MALS verified) (Cat. No. CD4-H5259) is more than 95% and the molecular weight of this protein is around 150-170 kDa verified by SEC-MALS.
Immobilized Human / Cynomolgus / Rhesus macaque ROR1, Fc Tag (Cat. No. RO1-H5250) at 2 μg/mL (100 μL/well) can bind Anti-ROR1 Antibody, Human IgG1 with a linear range of 0.3-5 ng/mL (QC tested).
Immobilized Human Siglec-2, Fc Tag (Cat. No. CD2-H5253) at 2 μg/mL (100 μL/well) can bind Monoclonal Anti-Human Siglec-2 Antibody, Human IgG1 with a linear range of 2-62.5 ng/mL (QC tested).
Binding activity of FITC-Labeled Human BCMA and CD19 protein from two different vendors were evaluated by the FACS analysis. The result showed that ACRO's Star Staining FITC-Labeled Human BCMA (Cat. No. BCA-HF2H3) and CD19 (Cat. No. CD9-HF2H3) protein have a much higher binding activity than that of the other competitor.
5e5 of PBMCs were stained with AF555-Labeled Human CD19 (20-291), His Tag (Cat. No. CD9-HA2H7) and anti-CD3 antibody, washed and then analyzed with FACS. FITC signal was used to evaluate the expression of CD3+ T cells in PBMCs, and AF555 signal was used to evaluate the non-specific binding activity to PBMCs (QC tested).
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