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FGF-3

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FG3-H51H9 Human Human FGF-3 / HBGF-3 Protein, His Tag
FG3-H51H9-structure
FG3-H51H9-sds
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Part of Bioactivity data

FG3-H51H9-SPR
FGF-3 ELISA

Immobilized Human FGF-3, His Tag (Cat. No. FG3-H51H9) at 5 μg/mL (100 μL/well) can bind Human FGF R2 (IIIb), Fc Tag (Cat. No. FGB-H5256) with a linear range of 0.02-2.5 μg/mL (Routinely tested).

Protocol

Synonym Name

FGF-3,HBGF-3,Fibroblast growth factor 3

Background

Fibroblast growth factor 3 (FGF3), belonging to the family of fibroblast growth factors (FGFs), regulates several developmental processes, including brain patterning, branching morphogenesis and limb development, by binding, dimerizing and activating cell surface FGF receptors (FGFRs). FGF/FGFR complexes have been demonstrated to act as driving oncogenes in certain types of cancer to maintain the malignant properties of tumor cells in a cell autonomous manner. According to previous studies, it is speculated that FGF3 is upregulated in breast cancer and accelerates tumor growth and angiogenesis. Consequently, FGF3 has been considered as a potential target for breast cancer therapy.

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