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ComboXTM, Universal Tools for Your Antibody Drug Development
ComboX, A Combination of Universal Solutions

ComboX is a universal product brand meticulously crafted by ACROBiosystems, converging a diverse and high-quality product portfolio to provide comprehensive solutions for scientific research. "Combo", symbolizing combination, reflects our integration of diversified products to meet your varied needs from basic research to biopharmaceutical development. "X", representing infinite possibilities, embodies our highly diverse universal product line and comprehensive reagent support spanning from single components to multifaceted systems.

ComboX is not merely a tool but a trusted partner on your research journey. We eagerly anticipate collaborating with you to unlock the mysteries of science and explore the boundless potential of biopharmaceutical development.

Application-Ready Solutions

High Batch-to-Batch Consistency

Cost-Effective Innovation

*Please click on the product names below to find detailed information~

Protein G
Protein A-coupled Magnetic Beads

Antibody purification is a process used to isolate and obtain highly purified antibodies from a mixture of various proteins and molecules. For the purification of IgG, in most cases we choose to use Protein A or Protein G for affinity chromatography. This is because they specifically bind to the Fc segment of IgG, while they do not or only weakly bind to other heterogeneous protein.

Product Recommendation

Recombinant Protein G, His Tag (Cat. NO. RPG-S3140

Protein A-coupled Magnetic Beads (recommended for MPCLIA)(Cat. NO. MPC-A001

Buffers

Buffers are essential for optimizing biological assays. They maintain ideal conditions for biomolecules, minimize interference, stabilize components, enable sample preparation, and ensure reproducibility - all critical factors for reliable, high-performance assays.

Product Recommendation

ELISA Buffer Set-96T (Cat. No. EBS-001)

ELISA Buffer Set (Phosphate system, 96T) (Cat. No. EBS-002)

Dilution Buffer (Strengthen Blocking) (Cat. No. DB-02)

Nickel-coated plates

Nickel-coated plates leverage metal chelated affinity technology, utilizing the stable chelation of Ni²⁺-nitrilotriacetic acid (NTA) to efficiently capture His tag proteins, enabling rapid and precise identification of target proteins. This innovation has become an indispensable tool in antibody development, drug screening, and protein research, significantly advancing the progress of biomedical research.

Product Recommendation

Nickel Coated Plates, Clear, 12x8-Well Strips, White Frame (Cat. No. SP-19)

Cytokine Detection ELISA Kits

We provide high-quality ELISA products for biopharmaceutical research. The ClinMax™ series provides a list of ready-to-use immunoassay kits that have been validated in multiple types of biological samples. We currently offer quantitative assay kits for a variety of targets including biomarkers and cytokines. The kits are thoroughly validated to ensure inter- and intra-assay precision, specificity, accuracy, and sensitivity in analytical results.

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Cytokine ELISpot Assay Kits

Our ELISpot assay kits employ high-sensitivity single-cell level detection technology to precisely identify key cytokines secreted by T cells, including IFN-γ, IL-2, IL-4, and TNF-α, making them ideal for comprehensive immune response functional analysis. These kits enable the detection of functional states in live cells following antigen stimulation, offering exceptional specificity, high sensitivity, accurate quantification, and intuitive visualization capabilities.

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TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) is a detection technology that combines Fluorescence Resonance Energy Transfer (FRET) with Time-Resolved Fluorescence (TRF) measurement. By integrating the strengths of both FRET and TRF, TR-FRET offers high sensitivity, ease of use, and reliable results. It is well-suited for high-throughput screening and widely applicable in protein quantification, signaling pathway analysis, disease mechanism studies, and more.

Protein-Protein Interaction Kit (PPI)

Including TR-FRET binding assay kits and TR-FRET inhibitor screening kits: TR-FRET binding assay kits are primarily designed for validating molecular interactions, comparing and optimizing antibody affinities, evaluating ADCC/ADCP effector functions, and assessing antibody drug half-life. TR-FRET inhibitor screening kits are intended to evaluate the blocking capacity of compounds or biomolecules against target binding, making them particularly suitable for small molecule drug screening, drug function validation, and signaling pathway studies.

Toolbox

Including TR-FRET-specific reaction buffers, FA- or EU-labeled antibodies (acceptor/donor), and FA- or EU-labeled streptavidin. These universal tools provide researchers with greater flexibility and methodological versatility, enabling them to independently build TR-FRET detection systems tailored to different targets, binding pairs, or screening strategies. This supports innovative or specialized experimental needs across a variety of research scenarios.

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The CRISPR/Cas system can achieve highly flexible and specific targeting, can be modified and redirected, and has become one of the most efficient, simple, cost-effective, and easy-to-use technologies in existing gene editing and gene modification. It has been widely used in the study of tumor related gene functions, the establishment of tumor animal models, and the exploration of drug targets, greatly improving people's understanding of tumor genomics.

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GENIUS™ Nuclease is a nucleic acid digestion enzyme used to ensure the removal of any unwanted and residual DNA sequences in your final therapeutics, As a component used to ensure your final therapeutic meets regulatory requirements, we ensure that our nuclease uses no animal-derived components and no added lPTG.

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resDetect™ Residue Detection Kits

resDetect™ is our brand of reagent kits designed to follow international legal, regulatory requirements and guidelines for the detection of residual components. These kits cover various applications related to process-related residue detection for biopharmaceuticals, including antibody drugs, cell and gene therapies (CGT), vaccines, and more.

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Recombinant Factor C Endotoxin Fluorescent Assay Kit

The Recombinant Factor C Endotoxin Detection Kit is a novel endotoxin detection method based on the recombination technology. Recombinant Factor C, as the first component of the horseshoe crab coagulation cascade reaction, is activated by endotoxin. The activated Factor C can cleave the fluorogenic substrate and produce a fluorescent signal. The increase of fluorescence signal is positively correlated with the dosage of endotoxin.

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Mycoplasma Rapid Detection Kit

Mycoplasma contamination during the production of biological products—such as cell isolation, modification, and expansion, significant risks to patient safety. To ensure product quality and regulatory compliance, it is essential to confirm the absence of mycoplasma in final release testing. To streamline both in-process control and batch release testing, we offer a rapid, reliable mycoplasma detection kit compliant with European Pharmacopoeia 2.6.7.

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Premium/GMP Grade Cytokines

To support ongoing cell therapy manufacturers and developers, we have developed a wide array of high-quality cytokines for the in vitro culture of immune cells, stem cells, organoids, and various other cell types. We also offer Premium (Pre-GMP) and GMP grades for our cytokines to better meet the needs of various drug development stages and applications.

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Anti-CD3/CD28 coupled Magnetic Beads

ACROBiosystems focuses on supporting research related to cell therapy. Under a comprehensive GMP quality system, we have developed high-quality ActiveMax® GMP-grade CD3/CD28 antibody-coupled magnetic beads. These beads are combined with cell culture platforms, magnetic bead coupling technology, and flow cytometry analysis platforms. Rigorously validated for activity, they efficiently stimulate and expand T cells, accelerating your cell therapy drug development process.

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Anti-CD3/Anti-CD28 Antibodies

ACROBiosystems, relying on a comprehensive GMP quality management system, has successfully developed GMP grade anti-CD3 antibodies and anti-CD28 antibodies, which have high safety and stability characteristics. After cell level verification, they can activate cultured T cells with high activity and have completed FDA DMF filing, fully assisting your cell therapy drug development process.

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Mogengel Matrix Basement Membrane Extracts

Through Acro Certify, we offer a broad range of matrix basement membrane extracts. Different versions including phenol red free, high concentration, iPSC culturing, and organoid culturing are available to meet your specific needs! Our Mogengel matrix is a soluble basement membrane extract purified from LDEV-free genetically engineered mouse tumor cells, primarily composed of laminin, collagen IV, entactin, and heparan sulfate proteoglycan.

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RG (Research Grade) Laminin 521

Laminin 521 offers a defined surface for feeder-free culture of human pluripotent stem cells (PSCs). It maintains normal growth and stemness in ESC, iPSC, and MSC lines. Laminin 521 supports PSC growth for over 10 passages without karyotypic abnormalities and retains differentiation ability into all three germ layers.

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HEK293 Cell Culture Reagents

To meet the high-efficiency and high-yield demands of HEK293 cell culture, we have developed transfection reagents and expression enhancers specifically engineered for transient gene expression (TGE), recombinant protein production, and viral vector manufacturing. From efficient transfection to high-yield expression of target products, we deliver comprehensive support to streamline your workflow and achieve stable, high-performance production goals with ease.

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ACRO Quality

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