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Kat. Nr. | Arten | Produktbeschreibung | Struktur | Reinheit | Merkmal |
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CX4-H52D3 | Human | Human CXCR4 Full Length Protein, Flag,His Tag (Detergent) | |||
CX4-H5219 | Human | Human CXCR4 / CD184 Full Length Protein (VLP) | |||
CX4-H5269 | Human | Human CXCR4 / CD184 Protein, Fc Tag |
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Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
---|---|---|---|---|---|---|---|---|---|---|
Plerixafor | SDZ-SID-791; JM-3100; JKL-169; AMD-3100; PLR-001; LM-3100 | Approved | Genzyme Corp | Mozobil, Mobozil, 释倍灵 | United States | Lymphoma, Non-Hodgkin; Multiple Myeloma | Genzyme Corp | 2008-12-15 | Lymphoma, Non-Hodgkin; Pulmonary Fibrosis; Rejection of organ transplantation; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukopenia; Colorectal Neoplasms; Agranulocytosis; Lymphopenia; Multiple Myeloma; Lymphoma; Leukemia, Myeloid, Acute; Pulmonary Disease, Chronic Obstructive; Granulomatous Disease, Chronic; Adenocarcinoma; Leukemia, Lymphocytic, Chronic, B-Cell; Anemia, Sickle Cell; Bone metastases; Fanconi Anemia; Pancreatic Neoplasms; Hodgkin Disease; Myelodysplastic Syndromes; Coronavirus Disease 2019 (COVID-19); Primary Graft Dysfunction; Warts; WHIM syndrome; Neutropenia; Infections; Wiskott-Aldrich Syndrome; Cystic Fibrosis; Hematopoietic stem cell transplantation (HSCT); Leukemia, Myelogenous, Chronic; Hematologic Neoplasms | Details |
Motixafortide | TN-14003; TF-14016; BL-8040; 4F-Benzoyl-TN14003; BKT-140; GFH-168; 4F-benzoyl-TN-14003 | Approved | Biokine, Kyoto University | APHEXDA | United States | Hematopoietic stem cell transplantation (HSCT) | Biolinerx Ltd | 2023-09-08 | Multiple Myeloma; Anemia, Sickle Cell; Adenocarcinoma; Lymphoma, T-Cell; Lymphoma, Non-Hodgkin; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Anemia, Aplastic; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Hematopoietic stem cell transplantation (HSCT); Myeloproliferative Disorders; Myelodysplastic Syndromes; Pancreatic Neoplasms; Hodgkin Disease; Esophageal Neoplasms; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic | Details |
Plerixafor | SDZ-SID-791; JM-3100; JKL-169; AMD-3100; PLR-001; LM-3100 | Approved | Genzyme Corp | Mozobil, Mobozil, 释倍灵 | United States | Lymphoma, Non-Hodgkin; Multiple Myeloma | Genzyme Corp | 2008-12-15 | Lymphoma, Non-Hodgkin; Pulmonary Fibrosis; Rejection of organ transplantation; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukopenia; Colorectal Neoplasms; Agranulocytosis; Lymphopenia; Multiple Myeloma; Lymphoma; Leukemia, Myeloid, Acute; Pulmonary Disease, Chronic Obstructive; Granulomatous Disease, Chronic; Adenocarcinoma; Leukemia, Lymphocytic, Chronic, B-Cell; Anemia, Sickle Cell; Bone metastases; Fanconi Anemia; Pancreatic Neoplasms; Hodgkin Disease; Myelodysplastic Syndromes; Coronavirus Disease 2019 (COVID-19); Primary Graft Dysfunction; Warts; WHIM syndrome; Neutropenia; Infections; Wiskott-Aldrich Syndrome; Cystic Fibrosis; Hematopoietic stem cell transplantation (HSCT); Leukemia, Myelogenous, Chronic; Hematologic Neoplasms | Details |
Motixafortide | TN-14003; TF-14016; BL-8040; 4F-Benzoyl-TN14003; BKT-140; GFH-168; 4F-benzoyl-TN-14003 | Approved | Biokine, Kyoto University | APHEXDA | United States | Hematopoietic stem cell transplantation (HSCT) | Biolinerx Ltd | 2023-09-08 | Multiple Myeloma; Anemia, Sickle Cell; Adenocarcinoma; Lymphoma, T-Cell; Lymphoma, Non-Hodgkin; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Anemia, Aplastic; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Hematopoietic stem cell transplantation (HSCT); Myeloproliferative Disorders; Myelodysplastic Syndromes; Pancreatic Neoplasms; Hodgkin Disease; Esophageal Neoplasms; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic | Details |
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
[68Ga]Pentixafor | Phase 3 Clinical | The University Of Iowa | Lymphoma, B-Cell, Marginal Zone; Cushing Syndrome; Sarcoidosis; Rejection of organ transplantation; Neuroendocrine Tumors; Myocarditis; Central Nervous System Lymphoma; Hyperaldosteronism | Details | |
90Y-Pentixather | Phase 2 Clinical | University Of Wurzburg, Technical University Of Munich | Multiple Myeloma; Central Nervous System Lymphoma | Details | |
177Lu-Pentixather | Phase 2 Clinical | Technical University Of Munich, Nantes University Hospital, University Of Wurzburg | Leukemia; Multiple Myeloma | Details | |
Ulocuplumab | MDX-1338; BMS-936564 | Phase 2 Clinical | Bristol-Myers Squibb Company | Leukemia; Solid tumours; Multiple Myeloma; Lymphoma, Follicular; Leukemia, B-Cell; Waldenstrom Macroglobulinemia; Leukemia, Myeloid, Acute; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
MSX-122 | Q-122; WZ-40; MSX-122 | Phase 2 Clinical | Altiris Therapeutics | Solid tumours; Hot Flashes | Details |
PTX-9908 | PTX-9908 | Phase 2 Clinical | Pertinax Therapeutics | Carcinoma, Hepatocellular | Details |
Plerixafor/Tacrolimus Hydrate | MRG-001(MedRegen); AMD3100+FK506 | Phase 2 Clinical | MedRegen LLC | Coronavirus Disease 2019 (COVID-19); Respiratory Distress Syndrome, Adult; Abdominal Injuries; Wounds and Injuries | Details |
NRP-2945 | NNZ-4945; NRP-2945 | Phase 2 Clinical | Neuren Pharmaceuticals Ltd | Epilepsy | Details |
GPC-100 | GPC-100 | Phase 2 Clinical | GPCR Therapeutics USA Inc | Multiple Myeloma | Details |
4-P-021 | 4P021; 4-P-021 | Phase 2 Clinical | 4P-Pharma Ltd, University of Bordeaux, Institut Pasteur De Lille | Coronavirus Disease 2019 (COVID-19) | Details |
CGT-1881 | CGT1881; CGT-1881 | Phase 2 Clinical | Cgenetech(Suzhou China) Co Ltd | Hematologic Neoplasms; Hematopoietic stem cell transplantation (HSCT); Multiple Myeloma; Lymphoma, Non-Hodgkin | Details |
LY-2510924 | T-134; LY-2510924 | Phase 1 Clinical | Eli Lilly And Company | Leukemia; Solid tumours; Carcinoma, Renal Cell; Small Cell Lung Carcinoma | Details |
AGT 103-T | AGT 103-T | Phase 1 Clinical | American Gene Technologies International Inc | HIV Infections | Details |
Balixafortide | POL-6326 | Phase 1 Clinical | Polyphor Ltd | Leukemia, Myelogenous, Chronic; Myelodysplastic Syndromes; Myeloproliferative Disorders; Multiple Myeloma; Breast Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Acute; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
JVS-100 | JVS-100; SRX-100; ACRX-100; GP-51801; GP51801 | Phase 1 Clinical | Cleveland Clinic | Heart Failure; Ischemia; Surgical Wound; Peripheral Arterial Disease | Details |
Dociparstat sodium | ODSH; CX-01; PGX-100; PGX-ODSH-2013-AML-1 | Phase 1 Clinical | Paringenix | Coronavirus Disease 2019 (COVID-19); Pancreatic Neoplasms; Myelodysplastic Syndromes; Protein-Losing Enteropathies; Pulmonary Disease, Chronic Obstructive; Leukemia, Myeloid, Acute; Acute Lung Injury | Details |
203-Lead Pentixather | Phase 1 Clinical | National Institutes Of Health, National Cancer Institute, Holden Comprehensive Cancer Center | Small Cell Lung Carcinoma; Lung Neoplasms | Details | |
212-Lead Pentixather | Phase 1 Clinical | National Institutes Of Health, National Cancer Institute, Holden Comprehensive Cancer Center | Small Cell Lung Carcinoma; Lung Neoplasms | Details | |
68Ga-Pentixather | 68Ga-Pentixather | Phase 1 Clinical | Peking Union Medical College Hospital | Multiple Myeloma | Details |
CXCR4 modified anti-BCMA CAR T cell therapy (Sichuan University) | Phase 1 Clinical | Sichuan University | Multiple Myeloma | Details | |
AD-214 | AD-214 | Phase 1 Clinical | Addpharma Inc, Adalta Ltd | Lung Diseases, Interstitial; Gastroesophageal Reflux | Details |
X-4136 | X-4136 | Clinical | X4 Pharmaceuticals Inc | Lymphoma, B-Cell; Uterine Cervical Neoplasms; Melanoma | Details |
[18F]AlF-NOTA-pentixather | Sichuan Provincial People'S Hospital | Details | |||
[68Ga]Pentixafor | Phase 3 Clinical | The University Of Iowa | Lymphoma, B-Cell, Marginal Zone; Cushing Syndrome; Sarcoidosis; Rejection of organ transplantation; Neuroendocrine Tumors; Myocarditis; Central Nervous System Lymphoma; Hyperaldosteronism | Details | |
90Y-Pentixather | Phase 2 Clinical | University Of Wurzburg, Technical University Of Munich | Multiple Myeloma; Central Nervous System Lymphoma | Details | |
177Lu-Pentixather | Phase 2 Clinical | Technical University Of Munich, Nantes University Hospital, University Of Wurzburg | Leukemia; Multiple Myeloma | Details | |
Ulocuplumab | MDX-1338; BMS-936564 | Phase 2 Clinical | Bristol-Myers Squibb Company | Leukemia; Solid tumours; Multiple Myeloma; Lymphoma, Follicular; Leukemia, B-Cell; Waldenstrom Macroglobulinemia; Leukemia, Myeloid, Acute; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
MSX-122 | Q-122; WZ-40; MSX-122 | Phase 2 Clinical | Altiris Therapeutics | Solid tumours; Hot Flashes | Details |
PTX-9908 | PTX-9908 | Phase 2 Clinical | Pertinax Therapeutics | Carcinoma, Hepatocellular | Details |
Plerixafor/Tacrolimus Hydrate | MRG-001(MedRegen); AMD3100+FK506 | Phase 2 Clinical | MedRegen LLC | Coronavirus Disease 2019 (COVID-19); Respiratory Distress Syndrome, Adult; Abdominal Injuries; Wounds and Injuries | Details |
NRP-2945 | NNZ-4945; NRP-2945 | Phase 2 Clinical | Neuren Pharmaceuticals Ltd | Epilepsy | Details |
GPC-100 | GPC-100 | Phase 2 Clinical | GPCR Therapeutics USA Inc | Multiple Myeloma | Details |
4-P-021 | 4P021; 4-P-021 | Phase 2 Clinical | 4P-Pharma Ltd, University of Bordeaux, Institut Pasteur De Lille | Coronavirus Disease 2019 (COVID-19) | Details |
CGT-1881 | CGT1881; CGT-1881 | Phase 2 Clinical | Cgenetech(Suzhou China) Co Ltd | Hematologic Neoplasms; Hematopoietic stem cell transplantation (HSCT); Multiple Myeloma; Lymphoma, Non-Hodgkin | Details |
LY-2510924 | T-134; LY-2510924 | Phase 1 Clinical | Eli Lilly And Company | Leukemia; Solid tumours; Carcinoma, Renal Cell; Small Cell Lung Carcinoma | Details |
AGT 103-T | AGT 103-T | Phase 1 Clinical | American Gene Technologies International Inc | HIV Infections | Details |
Balixafortide | POL-6326 | Phase 1 Clinical | Polyphor Ltd | Leukemia, Myelogenous, Chronic; Myelodysplastic Syndromes; Myeloproliferative Disorders; Multiple Myeloma; Breast Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Acute; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
JVS-100 | JVS-100; SRX-100; ACRX-100; GP-51801; GP51801 | Phase 1 Clinical | Cleveland Clinic | Heart Failure; Ischemia; Surgical Wound; Peripheral Arterial Disease | Details |
Dociparstat sodium | ODSH; CX-01; PGX-100; PGX-ODSH-2013-AML-1 | Phase 1 Clinical | Paringenix | Coronavirus Disease 2019 (COVID-19); Pancreatic Neoplasms; Myelodysplastic Syndromes; Protein-Losing Enteropathies; Pulmonary Disease, Chronic Obstructive; Leukemia, Myeloid, Acute; Acute Lung Injury | Details |
203-Lead Pentixather | Phase 1 Clinical | National Institutes Of Health, National Cancer Institute, Holden Comprehensive Cancer Center | Small Cell Lung Carcinoma; Lung Neoplasms | Details | |
212-Lead Pentixather | Phase 1 Clinical | National Institutes Of Health, National Cancer Institute, Holden Comprehensive Cancer Center | Small Cell Lung Carcinoma; Lung Neoplasms | Details | |
68Ga-Pentixather | 68Ga-Pentixather | Phase 1 Clinical | Peking Union Medical College Hospital | Multiple Myeloma | Details |
CXCR4 modified anti-BCMA CAR T cell therapy (Sichuan University) | Phase 1 Clinical | Sichuan University | Multiple Myeloma | Details | |
AD-214 | AD-214 | Phase 1 Clinical | Addpharma Inc, Adalta Ltd | Lung Diseases, Interstitial; Gastroesophageal Reflux | Details |
X-4136 | X-4136 | Clinical | X4 Pharmaceuticals Inc | Lymphoma, B-Cell; Uterine Cervical Neoplasms; Melanoma | Details |
[18F]AlF-NOTA-pentixather | Sichuan Provincial People'S Hospital | Details |
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