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CD3

Brief Information

Name:T cell surface glycoprotein CD3
Target Synonym:CD3 Complex
Number of Launched Drugs:7
Number of Drugs in Clinical Trials:159
Lastest Research Phase:Approved

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Part of Bioactivity data

CDE-BV84G0-Cell-based assay
 CD3 FACS

5e5 of Jurkat cells were stained with 100 μL of 0.3 μg/mL of Biotinylated Anti-Human CD3 Antibody, Mouse IgG2a,Avitag (Clone: OKT3), premium grade (Cat. No. CDE-BV84G0) and isotype control antibody respectively, washed and then followed by PE-SA and analyzed with FACS (Routinely tested).

CDE-M532-Cell-based assay
 CD3 FACS

2e5 of Jurkat cells were stained with 100 μL of 1 μg/mL of Monoclonal Anti-Human CD3 Antibody, Mouse IgG1 (UCHT1) (Cat. No. CDE-M532) and isotype control antibody respectively, washed and then followed by PE-anti mouse IgG1 antibody and analyzed with FACS (Routinely tested).

CDE-M532-ELISA
 CD3 ELISA

Immobilized Human CD3E&CD3D Heterodimer Protein (Cat. No. CDD-H52Wa) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG1 (UCHT1) (Cat. No. CDE-M532) with a linear range of 0.1-3 ng/mL (QC tested).

CDE-BV84G0-MALS-HPLC
CD3 MALS images

The purity of Biotinylated Anti-Human CD3 Antibody, Mouse IgG2a,Avitag (Clone: OKT3), premium grade (Cat. No. CDE-BV84G0) is more than 95% and the molecular weight of this protein is around 130-160 kDa verified by SEC-MALS.

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Mosunetuzumab RG-7828; BTCT-4465A; RO-7030816; CD20-TBD Approved Genentech Inc Lunsumio EU Lymphoma, Follicular Roche Registration Gmbh 2022-06-03 Lymphoma, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Follicular; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Lupus Erythematosus, Systemic; Lymphoma, Non-Hodgkin; Lymphoma; Leukemia, Lymphocytic, Chronic, B-Cell Details
Blinatumomab MEDI-538; MT-103; BiTE-MT-103; bscCD19xCD3; AMG-103 Approved Amgen Inc Blincyto, 倍利妥 United States Precursor B-Cell Lymphoblastic Leukemia-Lymphoma Amgen Inc 2014-12-03 Neoplasm, Residual; Leukemia, Myelogenous, Chronic; Leukemia; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Philadelphia Chromosome; Leukemia, B-Cell; Lymphoma, Non-Hodgkin; Lymphoma; Burkitt Lymphoma; Leukemia, Lymphocytic, Chronic, B-Cell Details
Teplizumab MGA-031; PRV-031; hOKT3-γ1-ala-ala; hOKT3-gamma-1-ala-ala Approved Tolerance Therapeutics Inc TZIELD United States Diabetes Mellitus, Type 1 Provention Bio Inc 2022-11-17 Diabetes Mellitus, Type 1; Rejection of renal transplantation; Glucose Intolerance; Hypoglycemia; Psoriasis; Diabetes Mellitus, Experimental Details
Teclistamab JNJ-64007959; JNJ-64007957; JNJ-7957 Approved Janssen Global Services Llc, Genmab A/S TECAYLI EU Multiple Myeloma Janssen-Cilag International Nv 2022-08-23 Hematologic Diseases; Hematologic Neoplasms; Smoldering Multiple Myeloma; Multiple Myeloma Details
Tebentafusp IMC-gp-100; IMC-gp100; ImmTAC-gp-100 Approved Immunocore Ltd KIMMTRAK United States Uveal melanoma Immunocore Ltd 2022-01-25 Uveal melanoma; Melanoma Details
Epcoritamab GEN-3013; ABBV-GMAB-3013 Approved Genmab A/S, Abbvie Inc EPKINLY, TEPKINLY, Tepkinly United States Lymphoma, Large B-Cell, Diffuse Genmab Us Inc 2023-05-19 Lymphoma, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Large B-Cell, Diffuse; Primary mediastinal B cell lymphoma; Richter's Syndrome; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
Mouse monoclonal antibody against human CD3 antigen of T lymphocyte (Wuhan Institute of Biological Products) Approved Wuhan Institute Of Biological Products Co Ltd Mainland China Rejection of organ transplantation Wuhan Institute Of Biological Products Co Ltd 1999-01-01 Rejection of organ transplantation Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Catumaxomab LP000 Phase 3 Clinical Trion Research, Neovii Biotech Gmbh Ovarian Neoplasms; Stomach Neoplasms; Carcinoma; Neoplasms; Carcinoma, Ovarian Epithelial; Colonic Neoplasms; Urinary Bladder Neoplasms; Ascites; Breast Neoplasms Details
CC-1 CC-1 Phase 1 Clinical University Of Tubingen, German Cancer Research Center (Dkfz) Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms; Carcinoma, Squamous Cell Details
Vibecotamab XmAb-14045 Phase 2 Clinical Xencor Inc Leukemia, Myeloid; Myelodysplastic Syndromes; Blastic Plasmacytoid Dendritic Cell Neoplasm; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Acute Details
ONO-4685 ONO-4685 Phase 1 Clinical Merus Nv Psoriasis; Lymphoma, T-Cell; Plaque psoriasis Details
TNB-585 AMG-340; TNB-585 Phase 1 Clinical Teneobio Inc, Amgen Inc Prostatic Neoplasms, Castration-Resistant Details
REGN-4336 REGN-4336 Phase 2 Clinical Regeneron Pharmaceuticals Inc Prostatic Neoplasms, Castration-Resistant Details
GBR-1342 GBR-1342; ISB-1342 Phase 1 Clinical Glenmark Pharmaceuticals Ltd Multiple Myeloma Details
BS-006 BS-006 Phase 1 Clinical Wuhan Binhui Biotechnology Co Ltd Solid tumours; Neoplasms; Uterine Cervical Neoplasms; Melanoma Details
QLS-31905 QLS-31905 Phase 2 Clinical Qilu Pharmaceutical Co Ltd Solid tumours; Neoplasms Details
ISB-2001 ISB-2001 Phase 1 Clinical Ichnos Sciences Sa Multiple Myeloma Details
CCW-702 CCW-702 Phase 1 Clinical The Scripps Research Institute Inc, Abbvie Inc Prostatic Neoplasms Details
RG-6007 RO-7283420; RG-6007 Phase 1 Clinical F. Hoffmann-La Roche Ltd Leukemia, Myeloid, Acute Details
CC-3 CC-3 Phase 1 Clinical Eberhard Karls University Of Tubingen, Germany Colorectal Neoplasms; Gastrointestinal Neoplasms Details
CD30 biAb-AATC(The Medical College Of Wisconsin Nonprofit) Phase 2 Clinical The Medical College Of Wisconsin Nonprofit Lymphoma, B-Cell; Solid tumours; Leukemia; Chondrosarcoma; Neoplasms; Hodgkin Disease; Neuroblastoma; Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Cutaneous Details
GEN-1047 GEN-1047 Phase 2 Clinical Genmab A/S Carcinoma, Non-Small-Cell Lung Details
HBM-7022 HBM-7022; AZD-5863 Phase 2 Clinical Harbour Biomed Esophageal Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Neoplasms; Digestive System Neoplasms; Esophageal adenocarcinoma; Carcinoma, Pancreatic Ductal; Gastrointestinal Neoplasms Details
[89Zr]Zr-BI-764532 Phase 1 Clinical C.H. Boehringer Sohn Ag & Co. Kg, Boehringer Ingelheim Gmbh Small Cell Lung Carcinoma; Carcinoma, Neuroendocrine Details
JNJ-80948543 JNJ-80948543 Phase 1 Clinical Janssen Research & Development Llc Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
Plamotamab XmAb-13676 Phase 1 Clinical Xencor Inc Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
BC-3448 BC3448; BC-3448 Phase 1 Clinical Wuxi Zhikang Hongyi Biological Technology Co Ltd Solid tumours Details
Anti-EGFR-bispecific antibody armed activated T-cell therapy (Memorial Sloan Kettering Cancer Center) Phase 1 Clinical Memorial Sloan Kettering Cancer Center Pancreatic Neoplasms Details
CD3/CD19 neg allogeneic BMT (National Institute of Allergy and Infectious Diseases/University of Pittsburgh) Phase 2 Clinical National Institute Of Allergy And Infectious Diseases (Niaid), University Of Pittsburgh Primary Immunodeficiency Diseases; Female Urogenital Diseases; Inflammation Details
JNJ-63898081 JNJ-8081; JNJ-63898081 Phase 1 Clinical Janssen Global Services Llc Neoplasms Details
WVT-078(Novartis Pharma) WVT-078 Phase 1 Clinical Novartis Pharma Ag Multiple Myeloma Details
IBI-389 IBI-389 Phase 1 Clinical Innovent Biologics(Suzhou) Co Ltd Solid tumours; Neoplasms Details
RO7515629 RO7515629; RO-7515629; RG-6353 Phase 2 Clinical F. Hoffmann-La Roche Ag Ovarian Neoplasms; Carcinoma, Renal Cell; Pancreatic Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
ABBV-383 ABBV-383; TNB-383B Phase 3 Clinical Teneobio Inc, Abbvie Inc Multiple Myeloma Details
XmAb-819 XmAb-819 Phase 1 Clinical Xencor Inc Kidney Neoplasms; Carcinoma, Renal Cell Details
JANX-008 EGFR-TRACTr; JANX008; JANX-008 Phase 1 Clinical Janux Therapeutics Inc Solid tumours; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
EMB-06 EMB-06; EMB06 Phase 2 Clinical Shanghai Epimab Biotherapeutics, Inc Multiple Myeloma Details
Forimtamig RG-6234 Phase 1 Clinical F. Hoffmann-La Roche Ltd Multiple Myeloma Details
Imvotamab IGM-2323 Phase 2 Clinical Igm Biosciences Inc Lymphoma, B-Cell, Marginal Zone; Arthritis, Rheumatoid; Lymphoma, Large B-Cell, Diffuse; Lupus Erythematosus, Cutaneous; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lupus Erythematosus, Systemic; Arthritis; Lymphoma, Non-Hodgkin Details
PF-07062119 PF-07062119 Phase 1 Clinical Pfizer Pharmaceuticals Ltd (China) Stomach Neoplasms; Adenocarcinoma; Gastrointestinal Neoplasms; Large intestine neoplasm Details
A-319 A-319 Phase 1 Clinical Evive Biotech Ltd Lymphoma, B-Cell; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, B-Cell Details
GR-1901 GR1901; GR-1901 Phase 1 Clinical Chongqing Zhixiang Jintai Biopharmaceutical Co Ltd Leukemia, Myeloid, Acute Details
HPN-536 HPN-536 Phase 2 Clinical Harpoon Therapeutics Neoplasms Details
JNJ-70218902 JNJ-70218902 Phase 1 Clinical Janssen Global Services Llc Neoplasms Details
AMG-794 AMG-794 Phase 1 Clinical Amgen Inc Carcinoma, Ovarian Epithelial; Carcinoma, Non-Small-Cell Lung Details
RO-7425781 RO-7425781 Phase 1 Clinical F. Hoffmann-La Roche Ltd Multiple Myeloma Details
JCAR-014 JCAR-014; JCAR021 Phase 2 Clinical Fred Hutchinson Cancer Research Center, Memorial Sloan Kettering Cancer Center, Seattle Children'S Research Institute, Juno Therapeutics Inc Lymphoma, B-Cell; Leukemia; Leukemia, Lymphoid; Hodgkin Disease; Lymphoma, Large B-Cell, Diffuse; Candidiasis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Mantle-Cell; Primary mediastinal B cell lymphoma; Leukemia, B-Cell; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
MBS-303 MBS-303 Phase 2 Clinical Beijing Mabworks Biotech Co Ltd Lymphoma, B-Cell; Lymphoma, Non-Hodgkin Details
IMC-C103C IMC-C103C; RG-6290 Phase 2 Clinical Immunocore Ltd Solid tumours Details
JNJ-63709178 JNJ-9178; CNTO-9958; JNJ-63709178 Phase 1 Clinical Janssen Global Services Llc, Genmab A/S Leukemia, Myeloid, Acute Details
Pavurutamab AMG-701 Phase 1 Clinical Amgen Inc Multiple Myeloma Details
AMG-562 AMG-562 Phase 1 Clinical Amgen Inc Lymphoma, Large B-Cell, Diffuse; Lymphoma, Follicular; Lymphoma, Mantle-Cell Details
NG-641 EnAd-FAP-BiTE; EnAd-FAP-Tac; NG-641; NG-aFAP Phase 1 Clinical Akamis Bio Ltd, University Of Oxford Squamous Cell Carcinoma of Head and Neck; Neoplasms, Glandular and Epithelial; Neoplasm Metastasis Details
ICP-B02 CM-355; ICP-B02 Phase 2 Clinical Beijing Tiannuo Jiancheng Pharmaceutical Technology Co Ltd, Keymed Biosciences Co Ltd Hematologic Neoplasms; Hematoma; Lymphoma; Lymphoma, Non-Hodgkin Details
ND003 ND003 Phase 1 Clinical Numab Therapeutics Ag Solid tumours; Asthma Details
Xaluritamig AMG-509 Phase 1 Clinical Xencor Inc, Amgen Inc Prostatic Neoplasms, Castration-Resistant Details
AZD-0486 TNB-486; AZD-0486; AZD0486 Phase 2 Clinical Teneobio Inc, Astrazeneca Plc Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Follicular; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin Details
hEGFRvIII-CD3 Bi-scFv Phase 1 Clinical Duke University Glioblastoma; Glioma Details
Emirodatamab AMG-427 Phase 1 Clinical Amgen Inc Leukemia, Myeloid, Acute Details
Cevostamab RG-6160; BFCR-4350A; RO-7187797 Phase 2 Clinical Genentech Inc Multiple Myeloma Details
Y-150(Wuhan Yzy Biopharma/CSPC Pharmaceutical) Y-150; Y150 Phase 1 Clinical Wuhan Yzy Biopharma Co Ltd, CSPC Pharmaceutical Group Ltd Multiple Myeloma Details
CLN-978 CLN-978 Phase 1 Clinical Adimab LLC Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Non-Hodgkin Details
ASP-2138 ASP-2138 Phase 1 Clinical Astellas Pharma Global Development Inc, Xencor Inc Stomach Neoplasms; Esophageal Neoplasms; Pancreatic Neoplasms Details
A-337 A-337 Phase 1 Clinical Evive Biotech Ltd Solid tumours; Neoplasms Details
Anti-CD3/humanized 3F8 bispecific antibody-activated T lymphocytes (University of Virginia) Phase 2 Clinical University Of Virginia Neuroblastoma Details
HPN-424 HPN-424 Phase 2 Clinical Harpoon Therapeutics Prostatic Neoplasms Details
MGD-024 MGD-024 Phase 1 Clinical Macrogenics Inc Leukemia, Myelogenous, Chronic; Leukemia, Hairy Cell; Hodgkin Disease; Myelodysplastic Syndromes; Neoplasms; Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia, B-Cell; Leukemia, Myeloid, Acute Details
EX-105 EX-105; EX105 Phase 1 Clinical Guangzhou Excelmab Inc Solid tumours Details
TGI-6 TGI-6 Phase 1 Clinical Hefei TG ImmunoPharma Co Ltd Solid tumours; Colorectal Neoplasms Details
α/β CD3+/CD19+ cell depleted stem cell therapy (Mitchell Cairo) Phase 2 Clinical New York Medical College Leukemia; Anemia; Thalassemia; Hodgkin Disease; Anemia, Aplastic; Thrombocytopenia; Lymphoma, Non-Hodgkin; Kostmann Syndrome; Anemia, Sickle Cell Details
JNJ-87890387 JNJ-87890387 Phase 1 Clinical Janssen Research & Development Llc Solid tumours Details
Anti-CD3-anti-HER2-activated T cells Phase 2 Clinical Transtarget Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Prostatic Neoplasms Details
Runimotamab BTRC-4017A; RG-6194; RO-7227780 Phase 1 Clinical F. Hoffmann-La Roche Ltd Solid tumours; Neoplasms Details
Tepoditamab MCLA-117 Phase 1 Clinical Pharmaceutical Research Associates, Institute Gustave-Roussy, Merus Nv, Vu University Medical Center, Lgc Leukemia, Myeloid, Acute Details
Vixtimotamab T-564; AMV-564 Phase 1 Clinical Amphivena Therapeutics Inc Solid tumours; Myelodysplastic Syndromes Details
GR-1803 GR-1803 Phase 1 Clinical Chongqing Zhixiang Jintai Biopharmaceutical Co Ltd Multiple Myeloma Details
K-193 K-193 Phase 1 Clinical Beijing Lvzhu Biological Technology Co Ltd Lymphoma, B-Cell Details
GNC-035 quadr-specific antibody(baili) GNC-035 Phase 2 Clinical Sichuan Baili Pharmaceutical Co Ltd Solid tumours; Hematologic Neoplasms; Breast Neoplasms; Metastatic breast cancer; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
SAR-443216 SAR-443216 Phase 1 Clinical Sanofi Solid tumours; Stomach Neoplasms; Neoplasms; Breast Neoplasms; Lung Neoplasms Details
EX-101 EX-101; EX101 Phase 1 Clinical Guangzhou Excelmab Inc Solid tumours Details
OBT620 OBT620 Phase 1 Clinical Boehringer Ingelheim Gmbh, Oxford Biotherapeutics Ltd Small Cell Lung Carcinoma Details
JANX-007 JANX-007; PSMA-TRACTr Phase 1 Clinical Janux Therapeutics Inc Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms Details
EMB-07 EMB-07 Phase 1 Clinical Shanghai Epimab Biotherapeutics, Inc Solid tumours; Ovarian Neoplasms; Stomach Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Adenocarcinoma of Lung; Pancreatic Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms; Colorectal Neoplasms; Lymphoma; Uterine Neoplasms; Neoplasm Metastasis Details
BI-765049 BI-765049; OBT-624 Phase 1 Clinical Boehringer Ingelheim Gmbh Solid tumours; Head and Neck Neoplasms; Liver Neoplasms; Pancreatic Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms Details
TAK-186 EGFR x CD3 COBRA; MVC-101; TAK-186 Phase 2 Clinical Takeda Pharmaceutical Co Ltd Solid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Anti-CD3 monoclonal antibody (Jinan Tiankang Biological Products) Phase 2 Clinical Jinan Tiankang Biological Products Co Ltd Anemia, Aplastic Details
EX-103 EX-103; EX103 Phase 1 Clinical Guangzhou Excelmab Inc Arthritis, Rheumatoid; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
CX-904 CX-904 Phase 1 Clinical Amgen Inc, Cytomx Therapeutics Inc Solid tumours; Neoplasms Details
CN-201 CN-201 Phase 2 Clinical Tongrun Biomedicine (Shanghai) Co Ltd Lymphoma, B-Cell; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, B-Cell; Lymphoma, Non-Hodgkin Details
Oncolytic Virus R130(Yunying Medical) R-130-OV; R130; R-130 Phase 1 Clinical Shanghai Yunying Medical Technology Co Ltd Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms; Melanoma; Laryngeal Neoplasms; Pharyngeal Neoplasms; Lung Neoplasms; Fallopian Tube Neoplasms; Colorectal Neoplasms; Genital Neoplasms, Female; Bone Neoplasms; Peritoneal Neoplasms; Sarcoma; Osteosarcoma; Head and Neck Neoplasms; Brain Neoplasms; Otorhinolaryngologic Neoplasms; Small Cell Lung Carcinoma; Pancreatic Neoplasms; Nose Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Carcinoma; Carcinoma, Bronchogenic; Liver Neoplasms; Ovarian Neoplasms; Kidney Neoplasms Details
Cibisatamab CEA-TCB; RG-7802; RO-6958688; CEA-CD3 TCB Phase 2 Clinical F. Hoffmann-La Roche Ltd Solid tumours; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Rezetamig JNJ-8780; JNJ75348780; JNJ-75348780 Phase 1 Clinical Teneobio Inc Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
TQB-2934 TQB2934; TQB-2934 Phase 1 Clinical Nanjing Shunxin Pharmaceuticals Co Ltd Of Chiatai Tianqing Pharmaceutical Group Multiple Myeloma Details
Anti-CD3 and anti-HER2 BiTE-expressing T cell (MedImmune) Phase 2 Clinical University Of Michigan, Huazhong University Of Science And Technology, University Of Virginia Cancer Center, Medimmune Breast Neoplasms Details
Recombinant humanized anti-CD19/CD3 bispecific antibody(New Time Pharmaceutical) LNF-1904 Phase 1 Clinical Shandong New Time Pharmaceutical Co Ltd Lymphoma, B-Cell; Leukemia, B-Cell Details
MP0533 MP0533 Phase 2 Clinical Molecular Partners Ag Leukemia, Myeloid, Acute Details
ARB-202 ARB-202 Phase 1 Clinical Arbele Corp Liver Neoplasms; Biliary Tract Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Gastrointestinal Neoplasms Details
GNC-039 GNC-039 Phase 1 Clinical Sichuan Baili Pharmaceutical Co Ltd Solid tumours; Hematologic Neoplasms; Glioma; Neoplasm Metastasis Details
M-701 M-701 Phase 2 Clinical Wuhan Yzy Biopharma Co Ltd Hydrothorax; Neoplasms; Ascites; Pleural Effusion, Malignant; Carcinoma, Non-Small-Cell Lung Details
RG-6232 RG-6232 Phase 1 Clinical F. Hoffmann-La Roche Ltd Melanoma Details
CLN-049 CLN-049 Phase 1 Clinical University Of Tubingen, German Cancer Research Center (Dkfz) Myelodysplastic Syndromes; Leukemia, Myeloid, Acute Details
JY-016 JY-016 Phase 1 Clinical Beijing Jingyitaixiang Technology Development Co Ltd, Beijing Eastern Biotech Co Ltd Solid tumours; Colorectal Neoplasms; Lung Neoplasms Details
BCMA TriTAC HPN-217 Phase 1 Clinical Harpoon Therapeutics, Abbvie Inc Multiple Myeloma Details
BNT-142 BNT-142 Phase 2 Clinical Biontech Se Solid tumours Details
MGD-014 MGD-014 Phase 1 Clinical Macrogenics Inc HIV Infections Details
GEN3017 GEN-3017 Phase 2 Clinical Genmab A/S Hematologic Neoplasms; Hodgkin Disease; Lymphoma, Non-Hodgkin Details
Autologous T-cell therapy (anti-PSMA-CD3), Roger Williams Medical Center Phase 1 Clinical Roger Williams Medical Center Prostatic Neoplasms Details
Alnuctamab CC-93269; EM-901 Phase 2 Clinical Celgene Corp Multiple Myeloma Details
MOR-209/ES414 APVO-414; MOR-209; ES-414; MOR209 Phase 1 Clinical Emergent Prostatic Neoplasms Details
Flotetuzumab S-80880; MGD-006; RES-234 Phase 2 Clinical Macrogenics Inc Leukemia, Myelogenous, Chronic; Hematologic Neoplasms; Leukemia; Leukemia, Hairy Cell; Mastocytosis, Systemic; Hodgkin Disease; Blastic Plasmacytoid Dendritic Cell Neoplasm; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms, Plasma Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, B-Cell; Leukemia, Myeloid, Acute; Leukemia, Biphenotypic, Acute Details
LBL-033 LBL-033 Phase 2 Clinical Nanjing Leads Biolabs Co Ltd Neoplasms Details
TQB-2825 TQB-2825 Phase 1 Clinical Wuxi Biologics Co Ltd Hematologic Neoplasms Details
SQZ-622(Novartis Pharma) SQZ-622 Phase 1 Clinical Novartis Pharma Ag Leukemia, Myeloid, Acute Details
BA-1202 BA-1202 Phase 1 Clinical Shandong Boan Biotechnology Co Ltd Solid tumours Details
Linvoseltamab REGN-5458 Phase 3 Clinical Regeneron Pharmaceuticals Inc Smoldering Multiple Myeloma; Multiple Myeloma; Monoclonal Gammopathy of Undetermined Significance; Renal Insufficiency, Chronic Details
ERY-974 ERY-974 Phase 1 Clinical Chugai Pharmaceutical Co Ltd Solid tumours; Carcinoma, Hepatocellular Details
CBA-1535 CBA-1535 Phase 1 Clinical Chiome Bioscience Inc Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms; Mesothelioma; Carcinoma, Non-Small-Cell Lung Details
TAK-280 MVC-280; TAK-280 Phase 2 Clinical Maverick Therapeutics Inc Solid tumours; Neoplasms; Neoplasm Metastasis Details
F-182112 F-182112; F182112 Phase 1 Clinical Shandong New Time Pharmaceutical Co Ltd Multiple Myeloma Details
RO-7428731 RO-7428731; RG-6156 Phase 1 Clinical F. Hoffmann-La Roche Ltd Glioblastoma Details
IBI-3003 IBI3003; IBI-3003 Phase 2 Clinical Innovent Biologics(Suzhou) Co Ltd Multiple Myeloma Details
ZG006 ZG006; ZG-006 Phase 2 Clinical Gensun Biopharma Inc, Suzhou Zelgen Biopharmaceuticals Co Ltd Solid tumours; Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Neuroendocrine Details
BC-004 BC-004 Phase 1 Clinical Shandong Buchang Pharmaceuticals Co Ltd Solid tumours; Breast Neoplasms Details
QLS-31904 QLS31904; QLS-31904 Phase 1 Clinical Qilu Pharmaceutical Co Ltd Solid tumours Details
GNR-084 GNR-084 Phase 2 Clinical Generium Pharmaceuticals, Iontas Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma Details
NVG-111 NVG-111 Phase 1 Clinical NovalGen Ltd Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Follicular; Melanoma; Carcinoma, Non-Small-Cell Lung; Leukemia, Lymphocytic, Chronic, B-Cell Details
Membrane bound ligand T-SIGn virus NG-348 Phase 1 Clinical Akamis Bio Ltd Neoplasms Details
Foralumab TZLS-401; NI-0401/α-CD3; NI-0401 Phase 2 Clinical Novimmune Sa, Bristol-Myers Squibb Company Respiratory Tract Infections; Diabetes Mellitus, Type 2; Non-alcoholic Fatty Liver Disease; Coronavirus Disease 2019 (COVID-19); Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis; Alzheimer Disease; Crohn Disease Details
XmAb-18968 XmAb-18968 Phase 1 Clinical The Medical College Of Wisconsin Nonprofit Leukemia, Myeloid, Acute Details
Acapatamab AMG-160 Phase 1 Clinical Amgen Inc Prostatic Neoplasms, Castration-Resistant; Carcinoma, Non-Small-Cell Lung Details
Recombinant humanized anti-BCMA/CD3 bispecific antibody(New Time Pharmaceutical) Phase 1 Clinical Shandong New Time Pharmaceutical Co Ltd Multiple Myeloma Details
RGV-004 RGV-004 Phase 1 Clinical Hangzhou Rongu Biotechnology Co Ltd Lymphoma, B-Cell Details
M-802(Wuhan Yzy Biopharma/CSPC Pharmaceutical) M-802 Phase 1 Clinical Wuhan Yzy Biopharma Co Ltd, CSPC Pharmaceutical Group Ltd Ovarian Neoplasms; Solid tumours; Stomach Neoplasms; Breast Neoplasms Details
SMET-12 SMET-12 Phase 2 Clinical Zhejiang Shimai Pharmaceutical Co Ltd Solid tumours Details
JNJ-78306358 JNJ-78306358; JNJ-6358 Phase 1 Clinical Janssen Research & Development Llc Solid tumours Details
REGN-5459 REGN-5459 Phase 2 Clinical Regeneron Pharmaceuticals Inc Multiple Myeloma; Renal Insufficiency, Chronic Details
CM-336(Connaught Biomedical Technology) CM-336 Phase 2 Clinical Keymed Biosciences Co Ltd Multiple Myeloma Details
Ubamatamab REGN-4018 Phase 2 Clinical Regeneron Pharmaceuticals Inc Ovarian Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Endometrial Neoplasms Details
JS-203 JS-203 Phase 1 Clinical Shanghai Junshi Biological Engineering Co Ltd Lymphoma, B-Cell; Lymphoma, Non-Hodgkin Details
1-A-46 BR-110; 1A46; 1-A-46; CMG1A46; CMG1A-46; BR110 Phase 2 Clinical Chengdu Chimagen Biosciences Co Ltd, Hisun Biopharmaceutical Co Ltd, BioRay Pharmaceutical Co Ltd Lymphoma, B-Cell; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Non-Hodgkin Details
BA-3182 BA-3182 Phase 1 Clinical Bioatla Solid tumours; Adenocarcinoma Details
RO-7293583 RO-7293583 Phase 1 Clinical F. Hoffmann-La Roche Ltd Skin Melanoma; Uveal melanoma; Melanoma Details
CM-350 CM-350 Phase 2 Clinical Keymed Biosciences Co Ltd Solid tumours Details
MBS-314 MBS-314 Phase 1 Clinical Beijing Mabworks Biotech Co Ltd Multiple Myeloma Details
CC-312 CC-312 Phase 1 Clinical CytoCares (Shanghai) Inc Hematologic Neoplasms; Lymphoma, B-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
Emfizatamab GNC-038 Phase 2 Clinical Sichuan Baili Pharmaceutical Co Ltd, SystImmune Inc Solid tumours; Lymphoma, Large B-Cell, Diffuse; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Extranodal NK-T-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Central Nervous System Lymphoma Details
Anti-CD3/anti-EGFR -activated T cells (Barbara Ann Karmanos Cancer Institute) Phase 2 Clinical Barbara Ann Karmanos Cancer Institute, University Of Virginia Glioblastoma; Pancreatic Neoplasms Details
APVO436 APVO-436 Phase 1 Clinical Aptevo Myelodysplastic Syndromes; Leukemia, Myeloid, Acute Details
BI-764532 BI-764532 Phase 2 Clinical C.H. Boehringer Sohn Ag & Co. Kg Small Cell Lung Carcinoma; Neoplasms; Neuroendocrine Tumors; Carcinoma, Neuroendocrine; Glioma Details
InHeAb-01 InHeAb-01; bsAB Clinical University Hospital Tuebingen Neoplasms Details
GB-261 GB-261 Phase 2 Clinical Genor Biopharma Co Ltd Lymphoma, B-Cell; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell Details
HPN-328 HPN-328 Phase 2 Clinical Harpoon Therapeutics Small Cell Lung Carcinoma Details
YK-012 YK012 Phase 1 Clinical Yikesite (Beijing) Pharmaceutical Technology Development Co Ltd Lymphoma, B-Cell Details
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