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FGF-6

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FG6-H51H4 Human Human FGF-6 Protein, His Tag
FG6-H51H4-structure
FG6-H51H4-sds
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Part of Bioactivity data

FG6-H51H4-SPR
FGF-6 SPR

Human FGF-6 Protein, His Tag (Cat. No. FG6-H51H4) immobilized on CM5 Chip can bind Human FGF R1, His Tag (Cat. No. FG1-H5223) with an affinity constant of 45 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol
FG6-H51H4-SPR
FGF-6 SPR

Human FGF-6 Protein, His Tag (Cat. No. FG6-H51H4) immobilized on CM5 Chip can bind Human FGF R4, Fc Tag (Cat. No. FG4-H5253) with an affinity constant of 13.4 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol

Synonym Name

FGF-6,Fibroblast growth factor 6,HST-2,HBGF-6

Background

Fibroblast growth factor 6 plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.For instance, FGF-6 might involve in MSCs proliferation and chondrogenic differentiation. Additionally, FGF-6 were identified as oncogene products. FGF6 is found over expressed in prostatic intraepithelial neoplasia and prostate cancer and promotes the proliferation of the transformed prostatic epithelial cells.

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