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Your Position: Start > Protein > CCL14 > CC4-H5249

Human CCL14 / HCC-1 Protein, His Tag

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  • Synonym
    C-C motif chemokine 14,Chemokine CC-1/CC-3,HCC-1/HCC-3,HCC-1(1-74),NCC-2,Small-inducible cytokine A14,CCL14,NCC2, SCYA14
  • Source
    Human CCL14, His Tag (CC4-H5249) is expressed from human 293 cells (HEK293). It contains AA Thr 20 - Asn 93 (Accession # Q16627-1).
    Predicted N-terminus: His
  • Molecular Characterization
    Online(Thr 20 - Asn 93) Q16627-1

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 10.7 kDa. The protein migrates as 14-15 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human CCL14, His Tag (Cat. No. CC4-H5249) SDS-PAGE gel

Human CCL14, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    CCL14 has weak activity on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induces intracellular Ca2+ changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and is inactive on T-lymphocytes, neutrophil
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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