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TRBC1

Brief Information

Name:TRBC1
Target Synonym:T cell receptor beta constant 1,TRBC1,V_segment Translation Product,BV05S1J2.2,TCRBC1,TCRB
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:5
Lastest Research Phase:Phase 2 Clinical

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Kat. Nr. Arten Produktbeschreibung Struktur Reinheit Merkmal
TR1-H82E6 Human Biotinylated Human TRBC1 Protein, His,Avitag™
TR1-H82E6-structure
TR1-H82E6-sds
TR1-H52H4 Human Human TRBC1 Protein, His Tag
TR1-H52H4-structure
TR1-H52H4-sds
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Synonym Name

T cell receptor beta constant 1,TRBC1

Background

The transmembrane protein, TCR, comprise of two disulphide-linked polypeptide chains: a α and β chain, a γ and δ chain. Each polypeptide chain consists of a variable and a constant region. TRBC1 is the constant region of T-cell receptor (TCR) beta chain.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
AUTO-4 (Autolus) AUTO-4 Phase 2 Clinical University College London Lymphoma, T-Cell, Peripheral; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell Details
STAR-0602 STAR-0602 Phase 2 Clinical Marengo Therapeutics Inc Solid tumours; Carcinoma; Abdominal Neoplasms; Papillomavirus Infections; Neoplasms; Vulvar Neoplasms; Urogenital Neoplasms; Lung Neoplasms; Epstein-Barr Virus Infections; Vulvar Diseases Details
Anti-TRBC1 CAR-T cell therapy (Shanghai General Hospital) Phase 1 Clinical Lymphoma, T-Cell, Peripheral; Hematologic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, T-Cell; Lymphoma, Large-Cell, Anaplastic Details
CAR-T Cell Therapy (Persongen Biotherapeutics) Phase 1 Clinical Persongen Biotherapeutics (Suzhou) Co Ltd Neoplasms Details
FT-819 FT-8198; FT-819; FT 8198 Phase 1 Clinical Memorial Sloan Kettering Cancer Center Lymphoma, B-Cell; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Lymphocytic, Chronic, B-Cell Details

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