Limited Edition Golden Llama is here! Check out how you can get one. Limited Edition Golden Llama is here! Check out how you can get one.
Happy Holiday! Limited Keychain here with your next orderHappy Holiday! Limited Keychain here with your next order
Time Limited Offer: Welcome Gift for New Customers ! Shipping Price Reduction for EU Regions
Project Name | Project Stage | Molecule Type | Host Species | Therapeutic Area | Indications |
ROR1 mAb - 01 | Lead | Hematological Malignancy,AutoImmunity | Solid tumor,Blood tumor |
Expression analysis of human ROR1 on HEK293/Human ROR1 Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human ROR1 Stable Cell Line or negative control cell using PE-labeled anti-human ROR1 antibody.
5e5 of anti-ROR1 CAR-293 cells were stained with 100 μL of 1:50 dilution (2 μL stock solution in 100 μL FACS buffer) of PE-Labeled Human ROR1 Protein, His Tag (Cat. No. RO1-HP2E3) and negative control protein respectively. PE signal was used to evaluate the binding activity (QC tested).
Anti-Human ROR1 mAb captured on CM5 chip via anti-mouse antibodies surface can bind Biotinylated Human / Cynomolgus / Rhesus macaque ROR1, His, Avitag (Cat. No. RO1-H82E6) with an affinity constant of 5.81 nM as determined in a SPR assay (Biacore T200) (Routinely tested).
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Zilovertamab vedotin | VLS-101; MK-2140 | Phase 3 Clinical | Oncternal Therapeutics Inc, University Of California San Diego | Breast Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Carcinoma, Non-Small-Cell Lung; Waldenstrom Macroglobulinemia; Burkitt Lymphoma; Lymphoma, T-Cell; Leukemia, Myeloid, Acute; Richter's Syndrome; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, B-Cell; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Neoplasms; Lymphoma, Large B-Cell, Diffuse; Pancreatic Neoplasms; Stomach Neoplasms; Lymphoma, B-Cell, Marginal Zone; Ovarian Neoplasms; Hematologic Neoplasms | Details |
Zilovertamab | UC-961 | Phase 2 Clinical | University Of California San Diego, Oncternal Therapeutics Inc | Lymphoma, B-Cell, Marginal Zone; Lymphoma, B-Cell; Immunoproliferative Disorders; Lymphatic Diseases; Immune System Diseases; Prostatic Neoplasms, Castration-Resistant; Lymphoma, Mantle-Cell; Breast Neoplasms; Lymphoproliferative Disorders; Lymphoma; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
ONCT-808 | ONCT-808 | Phase 2 Clinical | Oncternal Therapeutics Inc | Lymphoma, B-Cell; Neoplasms | Details |
Nebratamig | GNC-035 | Phase 2 Clinical | Solid tumours; Hematologic Neoplasms; Breast Neoplasms; Metastatic breast cancer; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell | Details | |
HG-030 | HG-030 | Phase 1 Clinical | Hitgen Inc | Solid tumours | Details |
EMB-07 | EMB-07 | Phase 1 Clinical | Shanghai Epimab Biotherapeutics, Inc | Solid tumours; Ovarian Neoplasms; Stomach Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Adenocarcinoma of Lung; Pancreatic Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms; Colorectal Neoplasms; Lymphoma; Uterine Neoplasms; Neoplasm Metastasis | Details |
PB-004 | PB004; PBA-0405; PB004 PureBIKE; PB-004 | Phase 1 Clinical | Pure Biologics SA | Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Sarcoma | Details |
PRGN-3007 | PRGN-3007 | Phase 1 Clinical | Precigen Inc | Hematologic Neoplasms; Solid tumours; Lymphoma, Large B-Cell, Diffuse; Triple Negative Breast Neoplasms; Lymphoma, Mantle-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
LYL-797 | LYL-797 | Phase 1 Clinical | Lyell Immunopharma Inc | Solid tumours; Triple Negative Breast Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
NVG-111 | NVG-111 | Phase 1 Clinical | NovalGen Ltd | Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Follicular; Melanoma; Carcinoma, Non-Small-Cell Lung; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
LCB-71 | CS-5001; LCB-71; ABL-202 | Phase 1 Clinical | Legochem Biosciences Inc, Abl Bio Inc | Solid tumours; Lymphoma, B-Cell; Hematologic Neoplasms; Lymphoma | Details |
SIM-201 | SIM-201; SIM-0201 | Phase 1 Clinical | Jiangsu Simcere Pharmaceutical Co Ltd | Solid tumours | Details |
Zilovertamab vedotin | VLS-101; MK-2140 | Phase 3 Clinical | Oncternal Therapeutics Inc, University Of California San Diego | Breast Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Carcinoma, Non-Small-Cell Lung; Waldenstrom Macroglobulinemia; Burkitt Lymphoma; Lymphoma, T-Cell; Leukemia, Myeloid, Acute; Richter's Syndrome; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, B-Cell; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Neoplasms; Lymphoma, Large B-Cell, Diffuse; Pancreatic Neoplasms; Stomach Neoplasms; Lymphoma, B-Cell, Marginal Zone; Ovarian Neoplasms; Hematologic Neoplasms | Details |
Zilovertamab | UC-961 | Phase 2 Clinical | University Of California San Diego, Oncternal Therapeutics Inc | Lymphoma, B-Cell, Marginal Zone; Lymphoma, B-Cell; Immunoproliferative Disorders; Lymphatic Diseases; Immune System Diseases; Prostatic Neoplasms, Castration-Resistant; Lymphoma, Mantle-Cell; Breast Neoplasms; Lymphoproliferative Disorders; Lymphoma; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
ONCT-808 | ONCT-808 | Phase 2 Clinical | Oncternal Therapeutics Inc | Lymphoma, B-Cell; Neoplasms | Details |
Nebratamig | GNC-035 | Phase 2 Clinical | Solid tumours; Hematologic Neoplasms; Breast Neoplasms; Metastatic breast cancer; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell | Details | |
HG-030 | HG-030 | Phase 1 Clinical | Hitgen Inc | Solid tumours | Details |
EMB-07 | EMB-07 | Phase 1 Clinical | Shanghai Epimab Biotherapeutics, Inc | Solid tumours; Ovarian Neoplasms; Stomach Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Adenocarcinoma of Lung; Pancreatic Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms; Colorectal Neoplasms; Lymphoma; Uterine Neoplasms; Neoplasm Metastasis | Details |
PB-004 | PB004; PBA-0405; PB004 PureBIKE; PB-004 | Phase 1 Clinical | Pure Biologics SA | Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Sarcoma | Details |
PRGN-3007 | PRGN-3007 | Phase 1 Clinical | Precigen Inc | Hematologic Neoplasms; Solid tumours; Lymphoma, Large B-Cell, Diffuse; Triple Negative Breast Neoplasms; Lymphoma, Mantle-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
LYL-797 | LYL-797 | Phase 1 Clinical | Lyell Immunopharma Inc | Solid tumours; Triple Negative Breast Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
NVG-111 | NVG-111 | Phase 1 Clinical | NovalGen Ltd | Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Follicular; Melanoma; Carcinoma, Non-Small-Cell Lung; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
LCB-71 | CS-5001; LCB-71; ABL-202 | Phase 1 Clinical | Legochem Biosciences Inc, Abl Bio Inc | Solid tumours; Lymphoma, B-Cell; Hematologic Neoplasms; Lymphoma | Details |
SIM-201 | SIM-201; SIM-0201 | Phase 1 Clinical | Jiangsu Simcere Pharmaceutical Co Ltd | Solid tumours | Details |
This web search service is supported by Google Inc.