0
Es befinden sich keine Waren im Warenkorb !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Start > Antibody > Olig2 > OL2-S456

Polyclonal Olig2 Antibody, Rabbit IgG

Order Now

  • Source
    Polyclonal Olig2 Antibody, Rabbit IgG is a polyclonal antibody purified from rabbit serum.
    Gene Synonyms: Oligo2, bHLHe19, oligodendrocyte transcription factor 2.
  • Species

    Rabbit polyclonal antibodies

  • Isotype

    Rabbit IgG

  • Antibody Type

    Polyclonal Antibody

  • Reactivity

    Mouse, rat, human, chicken, dog; Others have not been tested

  • Immunogen

    Mouse Olig2 peptide fused to GST.

  • Specificity

    Usually, it is easier to get a positive signal in sections of juvenile animals than that of adults. This antibody does not recognize Olig1 and Olig3.

  • Application
    ApplicationRecommended Usage
    IF1:200
  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, 50 mM Glycine, 50 mM Tris with 40% glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with blue ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Shipped at -20°C. Store at -20°C for 3 years;
    2. Shipped at -20°C. Store at -80°C for 5 years.
Immunostaining
 Olig2 IMMUNOSTAINING

2D cell staining: Immunofluorescent staining (10X) of cerebral organoid-derived neurons (CIPO-BWL001K) labeling Olig2 (Red) with purified OL2-S456 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain.

 Olig2 IMMUNOSTAINING

3D organoid staining: Immunofluorescent staining (4x or 10X) of cerebral organoid-(CIPO-BWL001K) labeling Olig2 (Green) with purified OL2-S456 at 1:200 dilution. DAPI (blue) was used as nuclear counterstain. TUJ1 (red) is a neural differentiation marker commonly used to label neural processes.

  • Background
    The oligodendrocyte transcription factor 2 (Olig2) is a basic helix-loop-helix transcription factor which is highly expressed in the oligodendrocyte-lineage cells and in oligodendroglial tumors of the brain as well. Olig2 is an essential regulator of ventral neuroectodermal progenitor cell fate, especially regulating key stages of early oligodendrocyte development. Olig2 has also been reported to act as a gene repressor to determine the cell fate of motor neurons in the spinal cord. Olig2 is a useful marker for primary and mature oligodendrocytes as well as a marker of malignant glioma.

    Zhang K, et al. Nat Commun. 2022;13(1):1423. doi: 10.1038/s41467-022-29068-z.

    Ono K, et al. Mol Cells. 2009;27(4):397-401. doi: 10.1007/s10059-009-0067-2.

    General Notes: FOR RESEARCH USE ONLY.
  • Clinical and Translational Updates

Comments (0)


Voraussichtlicher Liefertermin für vorrätige Produkte: 2 Arbeitstage

Price(USD) : $80.00

Price(USD) : $350.00

Promotion & Exhibitions



Datasheet & Documentation

Request for DMF
DMF (Drug Master File)

Related Products

New Product Launch

Questions & Comments

This web search service is supported by Google Inc.

totop

Nachricht schicken