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Your Position: Start > Antibody > Neuraminidase/NA (Influenza Virus) > NEE-M697

Monoclonal Anti-Influenza A [A/Thailand/1(KAN-1)/2004] NA (H5N1) Antibody, Human IgG1 (7B8) (MALS verified)

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  • Source

    Monoclonal Anti-Influenza A [A/Thailand/1(KAN-1)/2004] NA (H5N1) Antibody, Human IgG1 (7B8) is a chimeric monoclonal antibody recombinantly expressed from HEK293, which combines the variable region of a mouse monoclonal antibody with Human constant domain.

  • Clone

    7B8

  • Isotype

    Human IgG1 | Human Kappa

  • Conjugate

    Unconjugated

  • Antibody Type

    Recombinant Monoclonal

  • Reactivity

    Virus

  • Immunogen

    Recombinant Influenza A [A/Thailand/1(KAN-1)/2004(H5N1)] Neuraminidase (NA) Protein is expressed from human 293 cells.

  • Specificity

    Specifically recognizes Influenza A [A/Thailand/1(KAN-1)/2004(H5N1)] Neuraminidase (NA).

  • Application
    ApplicationRecommended Usage
    ELISA0.1-8 ng/mL 
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Purification

    Protein A purified/ Protein G purified

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Cross Verification

    This product No cross-reactivity in ELISA with
    Influenza B [Austria/1359417/2021] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5245).
    Influenza B [PHUKET/3073/2013] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5246).
    Influenza A [Darwin/6/2021] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5247).
    Influenza A [A/Darwin/9/2021 (H3N2)] Neuraminidase (NA) Protein, His Tag (Cat. No. NE2-V5249).
    Influenza A [turkey/Germany-MV/R2472/2014(H5N8)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5249).
    Influenza A [Guangdong/18SF020(H5N6)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524h) (Routinely tested).

SDS-PAGE
Neuraminidase/NA (Influenza Virus) SDS-PAGE

Monoclonal Anti-Influenza A [A/Thailand/1(KAN-1)/2004] NA (H5N1) Antibody, Human IgG1 (7B8) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
Neuraminidase/NA (Influenza Virus) MALS images

The purity of Monoclonal Anti-Influenza A [A/Thailand/1(KAN-1)/2004] NA (H5N1) Antibody, Human IgG1 (7B8) (Cat. No. NEE-M697) is more than 90% and the molecular weight of this protein is around 135-160 kDa verified by SEC-MALS.

Bioactivity-ELISA
 Neuraminidase/NA (Influenza Virus) ELISA

Immobilized Influenza A [A/Thailand/1(KAN-1)/2004(H5N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. HA1-V5245) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Influenza A [A/Thailand/1(KAN-1)/2004] NA (H5N1) Antibody, Human IgG1 (7B8) (Cat. No. NEE-M697) with a linear range of 0.06-1 ng/mL (QC tested).

 Neuraminidase/NA (Influenza Virus) ELISA

Influenza A [Sydney/5/2021(H1N1)] Neuraminidase (NA) Protein, His Tag/Influenza A [A/Victoria/4897/2022(H1N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524c)/Influenza A [Victoria/2570/2019(H1N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524e)/Influenza A [Wisconsin/588/2019(H1N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524k)/Influenza A [Wisconsin/67/2022(H1N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524m) combines well with Monoclonal Anti-Influenza A [A/Thailand/1(KAN-1)/2004] NA (H5N1) Antibody, Human IgG1 (7B8) (Cat. No. NEE-M697) (Routinely tested).

  • Background
    Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.
  • Clinical and Translational Updates

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