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Your Position: Start > Protein > Clec4a > CLA-H5253

Human Clec4a Protein, Fc Tag (MALS verified)

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  • Synonym
    CD367, CLECSF6, DCIR, DDB27, HDCGC13P, LLIR, hDCIR
  • Source
    Human Clec4a Protein, Fc Tag(CLA-H5253) is expressed from human 293 cells (HEK293). It contains AA Gln 70 - Leu 237 (Accession # Q9UMR7-1).
  • Molecular Characterization
    Clec4a Structure

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 46.4 kDa. The protein migrates as 50-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Clec4a SDS-PAGE

Human Clec4a Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
Clec4a MALS images

The purity of Human Clec4a Protein, Fc Tag (Cat. No. CLA-H5253) is more than 85% and the molecular weight of this protein is around 90-110 kDa verified by SEC-MALS.

  • Background
    This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
  • Clinical and Translational Updates

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