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PD-L1 IHC 5D3 Kit

For research use only.

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  • Background
    PD-L1 is an informative immunotherapy biomarker: Aberrant expression of PD-L1 on tumor and immune cells in the tumor microenvironment impedes anti-tumor immunity, allowing tumors to grow and metastasize. The PD-L1 IHC 5D3 Kit is a quick assay to detect PD-L1 across tumors to identify patients eligible for multiple targeted therapies. Kit product are manufactured in a dedicated GMP facility and are compliant with our ISO 13485 quality management system.
  • Product Details
    Assay TypeImmunohistochemistry
    AnalytePD-L1
    Format2ml/7.5ml/30ml
    ReactivityHuman
    SpeciesRabbit
    Regulatory StatusRUO
    Applicable PlatformLEICA BOND III、DAKO link 48
  • Materials Provided

    Recombinant Monoclonal Anti-PD-L1 Antibody, Rabbit (5D3)

    Antibody diluent

  • Application

    The kit is developed for use in the PD-L1 protein in the formalin-fixed, paraffin-embedded tissue. It is indicated as an aid in the assessment of PD-L1 expression in human tissues.

  • State

    Liquid

  • Storage

    Stored at 2°C to 8°C.

Control Sample
 PD-L1 CONTROL SAMPLE

Use ACRO PD-L1 5D3 kit to stain human tonsil tissue, positive cell membrane specific positive staining (staining intensity ≥ 1), no non-specific staining (staining intensity < 1) , no background staining (staining intensity < 1).

Cancer Sample
Consistency

ACRO PD-L1 5D3 and DAKO PD-L1 22C3 conformance verification, with a high consistency rate (>95%).

 PD-L1 CONSISTENCY PD-L1 CONSISTENCY PD-L1 CONSISTENCY

Use ACRO PD-L1 5D3 Kit and DAKO PD-L1 22C3 kit to stain non-small cell lung cancer, esophageal squamous cell carcinoma and liver cancer, respectively. The results showed that the staining effect was highly consistent.

Extensibility

ACRO PD-L1 5D3 kit expandable test: non-small cell lung cancer, esophageal carcinoma, gastric cancer, colorectal cancer and liver cancer.

 PD-L1 EXTENSIBILITY PD-L1 EXTENSIBILITY PD-L1 EXTENSIBILITY

Use ACRO PD-L1 5D3 kit to stain NSCLC, esophageal carcinoma, gastric cancer, colorectal cancer, liver cancer tissue samples respectively.

Applicability

ACRO PD-L1 5D3 can be available on the LEICA BOND III and DAKO Link 48 platform.

 PD-L1 APPLICABILITY PD-L1 APPLICABILITY PD-L1 APPLICABILITY

Use ACRO PD-L1 5D3 kit to stain NSCLC tissue samples at Leica BOND-III and Dako link 48.

  • Clinical and Translational Updates

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Drug Development Status

  • Number of Launched Drugs:7 Details
  • Number of Drugs in Clinical Trials:156 Details
  • Latest Research Phase:Phase 3 Clinical

Datasheet & Documentation

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DMF (Drug Master File)

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