0
Es befinden sich keine Waren im Warenkorb !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Start > Antibody > E8L (MPXV) > E8L-M573

Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) (MALS verified)

Order Now

  • Source

    Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) is a chimeric monoclonal antibody recombinantly expressed from HEK293, which combines the variable region of a mouse monoclonal antibody with Human constant domain.

  • Clone

    1C12

  • Isotype

    Human IgG1 | Human Kappa

  • Conjugate

    Unconjugated

  • Antibody Type

    Recombinant Monoclonal

  • Reactivity

    Virus

  • Immunogen

    Recombinant Monkeypox virus (strain Zaire-96-I-16) E8 derived from human 293 cells.

  • Specificity

    This product is a specific antibody specifically reacts with E8L (MPXV).

  • Application
    ApplicationRecommended Usage
    ELISA0.1-75 ng/mL 
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Purification

    Protein A purified/ Protein G purified

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
E8L (MPXV) SDS-PAGE

Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

SEC-MALS
E8L (MPXV) MALS images

The purity of Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) (Cat. No. E8L-M573) is more than 90% and the molecular weight of this protein is around 135-160 kDa verified by SEC-MALS.

Bioactivity-ELISA
 E8L (MPXV) ELISA

Immobilized Monkeypox virus (strain Zaire-96-I-16) E8L, His Tag (Cat. No. E8L-M52H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) (Cat. No. E8L-M573) with a linear range of 0.1-2 ng/mL (QC tested).

Bioactivity-SPR
 E8L (MPXV) SPR

Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) (Cat. No. E8L-M573) captured on Protein A Chip can bind Monkeypox virus (strain Zaire-96-I-16) E8L, His Tag (Cat. No. E8L-M52H3) with an affinity constant of 0.119 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

  • Background
    Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa , multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. E8L can Binds to chondroitin sulfate on the cell surface to provide virion attachment to target cell.
  • Clinical and Translational Updates

Comments (0)


Voraussichtlicher Liefertermin für vorrätige Produkte: 2 Arbeitstage

Price(EUR) : €370.00

Price(EUR) : €2460.00

Promotion & Exhibitions



Datasheet & Documentation

Request for DMF
DMF (Drug Master File)

Related Products

New Product Launch

Questions & Comments

This web search service is supported by Google Inc.

totop

Nachricht schicken