Anti-inhibitor coagulant complex (Baxalta) |
|
Approved |
Baxalta Incorporated |
Feiba, Prothromplex TOTAL |
United States |
Hemophilia A; Hemophilia B |
Baxalta Incorporated |
1979-12-21 |
Blood Coagulation Disorders; Blood Coagulation Disorders, Inherited; Hemophilia A; Hemophilia B; Cardiovascular Diseases |
Details
|
Human prothrombin complex (Nanyue Biopharming) |
|
Approved |
Hunan Ziguang Huhan Nanyue Pharmaceutical Co Ltd |
|
Mainland China |
Hemorrhage |
Hunan Ziguang Huhan Nanyue Pharmaceutical Co Ltd |
2019-09-05 |
Hemophilia B; Hemorrhage |
Details
|
Eptacog alfa (Novo Nordisk) |
NN-007 |
Approved |
Novo Nordisk A/S |
NiaStase, NovoSeven, 诺其 |
EU |
Factor VII Deficiency; Hemophilia A; Hemophilia B; Thrombasthenia |
Novo Nordisk A/S |
1996-02-23 |
Cerebral Hemorrhage; Spinal Diseases; Hemophilia A; Hemophilia B; Fibrosis; Hemorrhage; Stroke; Postpartum Hemorrhage; Factor VII Deficiency; Severe Dengue; Burns; Wounds and Injuries; Blood Loss, Surgical; Thrombasthenia; Acquired hemophilia |
Details
|
Etranacogene dezaparvovec |
AAV5-hFIX; AMT-061; CSL-222; AMT-060 |
Approved |
University College London, Uniqure Biopharma Bv |
HEMGENIX |
United States |
Hemophilia B |
Csl Behring |
2022-11-22 |
Hemophilia B |
Details
|
Human prothrombin complex (CSL Behring) |
BE-1116 |
Approved |
Csl Behring Llc |
Kcentra, Beriplex, Confidex |
|
|
|
|
Blood Coagulation Disorders; Coagulation Protein Disorders; Heart Failure; Heart Diseases; Hemorrhage; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Wounds and Injuries |
Details
|
Freeze-dried activated human blood coagulation factor Ⅶ concentrate containing factor Ⅹ (Kaketsuken/KM Biologics) |
MC-710 |
Approved |
Kaketsuken |
Byclot |
Japan |
Hemophilia A |
null |
2014-07-04 |
Hemophilia A |
Details
|
Human prothrombin complex concentrate (Guizhou Taibang Biological Products) |
|
Approved |
Guizhou Taibang Biological Products Co Ltd |
|
Mainland China |
Hypoprothrombinemias |
Guizhou Taibang Biological Products Co Ltd |
2013-07-31 |
Hypoprothrombinemias |
Details
|
Prothrombinex-VF (CSL Behring) |
|
Approved |
Csl Behring Llc |
|
Australia |
Hemorrhage |
Csl Behring Llc |
2014-10-01 |
Hemorrhage |
Details
|
Fidanacogene elaparvovec |
SPK-9001; PF-06838435 |
Approved |
The Children'S Hospital Of Philadelphia |
BEQVEZ |
Canada |
Hemophilia B |
Pfizer Inc |
2024-01-03 |
Hemophilia A; Hemophilia B |
Details
|
Prothrombin complex concentrate (Sanquin) |
|
Approved |
Sanquin Plasma Products Bv |
Cofact |
|
Hemorrhage |
Sanquin Plasma Products Bv |
2007-11-01 |
Hemorrhage |
Details
|
Emicizumab |
RG-6013; ACE-910; RO-5534262 |
Approved |
Genentech Inc, Chugai Pharmaceutical Co Ltd |
舒友立乐, Hemlibra |
United States |
Hemophilia A |
Genentech Inc |
2017-11-16 |
Hemophilia A; Hemorrhage; von Willebrand Disease, Type 3 |
Details
|
Factor XP Behring (CSL Behring) |
|
Approved |
Csl Behring Llc |
|
Spain |
Factor X Deficiency |
Csl Behring Llc |
2015-09-01 |
Factor X Deficiency |
Details
|
Eptacog alfa biosimilar (AryoGen Biopharma) |
|
Approved |
Aryogen Biopharma |
|
Iran |
Factor VII Deficiency; Hemophilia A; Hemophilia B; Thrombasthenia |
Aryogen Biopharma |
2014-01-01 |
Hemophilia A; Hemophilia B; Factor VII Deficiency; Thrombasthenia |
Details
|
Factor IX complex (Grifols) |
|
Approved |
Grifols Sa |
Profilnine |
United States |
Hemophilia B |
null |
1981-07-21 |
Intracranial Hemorrhages; Hemophilia B |
Details
|
Eptacog beta |
LR-769; rhFVIIa |
Approved |
Lfb Biotechnologies Sas, Revo Biologics Inc |
Sevenfact |
United States |
Hemophilia A; Hemophilia B |
Lfb Biotechnologies Sas |
2020-04-01 |
Hemophilia A; Hemophilia B |
Details
|
Human prothrombin complex (Octapharma) |
|
Approved |
Octapharma |
Ocplex, Octaplex, Pronativ |
Germany |
Hemorrhage |
Octapharma |
2003-03-14 |
Hemorrhage; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma |
Details
|
Eptacog alfa biosimilar (International Biotech Center Generium) |
GNR-001 |
Approved |
International Biotech Center Generium |
|
Russian Federation |
Hemophilia A |
International Biotech Center Generium |
2015-01-01 |
Hemophilia A |
Details
|
Human prothrombin complex (LFB) |
|
Approved |
Lfb Biotechnologies Sas |
KANOKAD |
France |
Hemorrhage |
Lfb Biotechnologies Sas |
2008-09-01 |
Hemorrhage |
Details
|
Human prothrombin complex (Tonrol Biopharmaceuticals) |
|
Approved |
Tonrol Bio-Pharmaceutical Co Ltd |
ProthoRAAS |
Mainland China |
Hemorrhage |
Shanghai Raas Blood Products Co Ltd |
1996-01-01 |
Hemophilia B; Hemorrhage |
Details
|
Human prothrombin complex (Guangdong Shuanglin) |
|
Approved |
Guangdong Shuanglin Bio-Pharmaceutical Co Ltd |
|
Mainland China |
Hemophilia B |
Guangdong Shuanglin Bio-Pharmaceutical Co Ltd |
2023-05-12 |
Hemophilia B |
Details
|
Human prothrombin complex (Shanghai Xinxing) |
|
Approved |
|
|
Mainland China |
Hemorrhage |
Shanghai Xinxing Medicine Co Ltd |
1997-01-01 |
Hemorrhage |
Details
|
Human prothrombin complex (Sinopharm Shanghai Plasma) |
|
Approved |
Sinopharm Shanghai Plasma-Derived Biotherapies Co Ltd |
|
Mainland China |
Hemorrhage |
Sinopharm Shanghai Plasma-Derived Biotherapies Co Ltd |
1997-01-01 |
Hemorrhage |
Details
|
Human prothrombin complex (Boya Bio-Pharmaceutical) |
|
Approved |
Boya Bio-Pharmaceutical Group Co Ltd |
|
Mainland China |
Hemorrhage |
Boya Bio-Pharmaceutical Group Co Ltd |
2020-12-02 |
Hemophilia B; Hemorrhage |
Details
|
Human prothrombin complex (Guangdong Wellen) |
|
Approved |
Guangdong Wellen Pharmaceutical Co Ltd |
|
Mainland China |
Hemorrhage |
Guangdong Wellen Pharmaceutical Co Ltd |
2020-10-21 |
Hemophilia B; Hemorrhage |
Details
|
Factor IX (Octapharma ) |
|
Approved |
Octapharma |
|
EU |
Hemophilia B |
Octapharma |
2001-12-23 |
Hemophilia B |
Details
|
Human prothrombin complex(Hebei Daan Pharmaceutical) |
|
Approved |
Hebei Daan Pharmaceutical Co Ltd |
|
Mainland China |
Hemorrhage |
Hebei Daan Pharmaceutical Co Ltd |
2020-01-01 |
Hemophilia B; Hemorrhage |
Details
|
Prothrombin complex concentrat (Taibang Biological Products) |
|
Approved |
Shandong Taibang Biological Products Co Ltd |
|
Mainland China |
Hemorrhage |
Shandong Taibang Biological Products Co Ltd |
2014-09-30 |
Hemorrhage; Antithrombin III Deficiency |
Details
|
Human prothrombin complex (Hualan Biological Engineering) |
|
Approved |
Hualan Genetic Engineering Co Ltd |
|
Mainland China |
Blood Coagulation Disorders; Factor X Deficiency |
Hualan Biological Engineering Inc |
1999-01-01 |
Blood Coagulation Disorders; Hemophilia B; Factor X Deficiency |
Details
|
Human prothrombin complex concentrate (Shanxi Kangbao Biological Products) |
|
Approved |
Shanxi Kangbao Biological Product Co Ltd |
|
Mainland China |
Hemorrhage |
Shanxi Kangbao Biological Product Co Ltd |
2019-09-17 |
Hemophilia B; Hemorrhage |
Details
|
Anti-inhibitor coagulant complex (Baxalta) |
|
Approved |
Baxalta Incorporated |
Feiba, Prothromplex TOTAL |
United States |
Hemophilia A; Hemophilia B |
Baxalta Incorporated |
1979-12-21 |
Blood Coagulation Disorders; Blood Coagulation Disorders, Inherited; Hemophilia A; Hemophilia B; Cardiovascular Diseases |
Details
|
Human prothrombin complex (Nanyue Biopharming) |
|
Approved |
Hunan Ziguang Huhan Nanyue Pharmaceutical Co Ltd |
|
Mainland China |
Hemorrhage |
Hunan Ziguang Huhan Nanyue Pharmaceutical Co Ltd |
2019-09-05 |
Hemophilia B; Hemorrhage |
Details
|
Eptacog alfa (Novo Nordisk) |
NN-007 |
Approved |
Novo Nordisk A/S |
NiaStase, NovoSeven, 诺其 |
EU |
Factor VII Deficiency; Hemophilia A; Hemophilia B; Thrombasthenia |
Novo Nordisk A/S |
1996-02-23 |
Cerebral Hemorrhage; Spinal Diseases; Hemophilia A; Hemophilia B; Fibrosis; Hemorrhage; Stroke; Postpartum Hemorrhage; Factor VII Deficiency; Severe Dengue; Burns; Wounds and Injuries; Blood Loss, Surgical; Thrombasthenia; Acquired hemophilia |
Details
|
Etranacogene dezaparvovec |
AAV5-hFIX; AMT-061; CSL-222; AMT-060 |
Approved |
University College London, Uniqure Biopharma Bv |
HEMGENIX |
United States |
Hemophilia B |
Csl Behring |
2022-11-22 |
Hemophilia B |
Details
|
Human prothrombin complex (CSL Behring) |
BE-1116 |
Approved |
Csl Behring Llc |
Kcentra, Beriplex, Confidex |
|
|
|
|
Blood Coagulation Disorders; Coagulation Protein Disorders; Heart Failure; Heart Diseases; Hemorrhage; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Wounds and Injuries |
Details
|
Freeze-dried activated human blood coagulation factor Ⅶ concentrate containing factor Ⅹ (Kaketsuken/KM Biologics) |
MC-710 |
Approved |
Kaketsuken |
Byclot |
Japan |
Hemophilia A |
null |
2014-07-04 |
Hemophilia A |
Details
|
Human prothrombin complex concentrate (Guizhou Taibang Biological Products) |
|
Approved |
Guizhou Taibang Biological Products Co Ltd |
|
Mainland China |
Hypoprothrombinemias |
Guizhou Taibang Biological Products Co Ltd |
2013-07-31 |
Hypoprothrombinemias |
Details
|
Prothrombinex-VF (CSL Behring) |
|
Approved |
Csl Behring Llc |
|
Australia |
Hemorrhage |
Csl Behring Llc |
2014-10-01 |
Hemorrhage |
Details
|
Fidanacogene elaparvovec |
SPK-9001; PF-06838435 |
Approved |
The Children'S Hospital Of Philadelphia |
BEQVEZ |
Canada |
Hemophilia B |
Pfizer Inc |
2024-01-03 |
Hemophilia A; Hemophilia B |
Details
|
Prothrombin complex concentrate (Sanquin) |
|
Approved |
Sanquin Plasma Products Bv |
Cofact |
|
Hemorrhage |
Sanquin Plasma Products Bv |
2007-11-01 |
Hemorrhage |
Details
|
Emicizumab |
RG-6013; ACE-910; RO-5534262 |
Approved |
Genentech Inc, Chugai Pharmaceutical Co Ltd |
舒友立乐, Hemlibra |
United States |
Hemophilia A |
Genentech Inc |
2017-11-16 |
Hemophilia A; Hemorrhage; von Willebrand Disease, Type 3 |
Details
|
Factor XP Behring (CSL Behring) |
|
Approved |
Csl Behring Llc |
|
Spain |
Factor X Deficiency |
Csl Behring Llc |
2015-09-01 |
Factor X Deficiency |
Details
|
Eptacog alfa biosimilar (AryoGen Biopharma) |
|
Approved |
Aryogen Biopharma |
|
Iran |
Factor VII Deficiency; Hemophilia A; Hemophilia B; Thrombasthenia |
Aryogen Biopharma |
2014-01-01 |
Hemophilia A; Hemophilia B; Factor VII Deficiency; Thrombasthenia |
Details
|
Factor IX complex (Grifols) |
|
Approved |
Grifols Sa |
Profilnine |
United States |
Hemophilia B |
null |
1981-07-21 |
Intracranial Hemorrhages; Hemophilia B |
Details
|
Eptacog beta |
LR-769; rhFVIIa |
Approved |
Lfb Biotechnologies Sas, Revo Biologics Inc |
Sevenfact |
United States |
Hemophilia A; Hemophilia B |
Lfb Biotechnologies Sas |
2020-04-01 |
Hemophilia A; Hemophilia B |
Details
|
Human prothrombin complex (Octapharma) |
|
Approved |
Octapharma |
Ocplex, Octaplex, Pronativ |
Germany |
Hemorrhage |
Octapharma |
2003-03-14 |
Hemorrhage; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma |
Details
|
Eptacog alfa biosimilar (International Biotech Center Generium) |
GNR-001 |
Approved |
International Biotech Center Generium |
|
Russian Federation |
Hemophilia A |
International Biotech Center Generium |
2015-01-01 |
Hemophilia A |
Details
|
Human prothrombin complex (LFB) |
|
Approved |
Lfb Biotechnologies Sas |
KANOKAD |
France |
Hemorrhage |
Lfb Biotechnologies Sas |
2008-09-01 |
Hemorrhage |
Details
|
Human prothrombin complex (Tonrol Biopharmaceuticals) |
|
Approved |
Tonrol Bio-Pharmaceutical Co Ltd |
ProthoRAAS |
Mainland China |
Hemorrhage |
Shanghai Raas Blood Products Co Ltd |
1996-01-01 |
Hemophilia B; Hemorrhage |
Details
|
Human prothrombin complex (Guangdong Shuanglin) |
|
Approved |
Guangdong Shuanglin Bio-Pharmaceutical Co Ltd |
|
Mainland China |
Hemophilia B |
Guangdong Shuanglin Bio-Pharmaceutical Co Ltd |
2023-05-12 |
Hemophilia B |
Details
|
Human prothrombin complex (Shanghai Xinxing) |
|
Approved |
|
|
Mainland China |
Hemorrhage |
Shanghai Xinxing Medicine Co Ltd |
1997-01-01 |
Hemorrhage |
Details
|
Human prothrombin complex (Sinopharm Shanghai Plasma) |
|
Approved |
Sinopharm Shanghai Plasma-Derived Biotherapies Co Ltd |
|
Mainland China |
Hemorrhage |
Sinopharm Shanghai Plasma-Derived Biotherapies Co Ltd |
1997-01-01 |
Hemorrhage |
Details
|
Human prothrombin complex (Boya Bio-Pharmaceutical) |
|
Approved |
Boya Bio-Pharmaceutical Group Co Ltd |
|
Mainland China |
Hemorrhage |
Boya Bio-Pharmaceutical Group Co Ltd |
2020-12-02 |
Hemophilia B; Hemorrhage |
Details
|
Human prothrombin complex (Guangdong Wellen) |
|
Approved |
Guangdong Wellen Pharmaceutical Co Ltd |
|
Mainland China |
Hemorrhage |
Guangdong Wellen Pharmaceutical Co Ltd |
2020-10-21 |
Hemophilia B; Hemorrhage |
Details
|
Factor IX (Octapharma ) |
|
Approved |
Octapharma |
|
EU |
Hemophilia B |
Octapharma |
2001-12-23 |
Hemophilia B |
Details
|
Human prothrombin complex(Hebei Daan Pharmaceutical) |
|
Approved |
Hebei Daan Pharmaceutical Co Ltd |
|
Mainland China |
Hemorrhage |
Hebei Daan Pharmaceutical Co Ltd |
2020-01-01 |
Hemophilia B; Hemorrhage |
Details
|
Prothrombin complex concentrat (Taibang Biological Products) |
|
Approved |
Shandong Taibang Biological Products Co Ltd |
|
Mainland China |
Hemorrhage |
Shandong Taibang Biological Products Co Ltd |
2014-09-30 |
Hemorrhage; Antithrombin III Deficiency |
Details
|
Human prothrombin complex (Hualan Biological Engineering) |
|
Approved |
Hualan Genetic Engineering Co Ltd |
|
Mainland China |
Blood Coagulation Disorders; Factor X Deficiency |
Hualan Biological Engineering Inc |
1999-01-01 |
Blood Coagulation Disorders; Hemophilia B; Factor X Deficiency |
Details
|
Human prothrombin complex concentrate (Shanxi Kangbao Biological Products) |
|
Approved |
Shanxi Kangbao Biological Product Co Ltd |
|
Mainland China |
Hemorrhage |
Shanxi Kangbao Biological Product Co Ltd |
2019-09-17 |
Hemophilia B; Hemorrhage |
Details
|