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Your Position: Start > Protein > CD171 > CD1-H52H4

Human CD171 Protein, His Tag (MALS verified)

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  • Synonym
    CD171,L1CAM
  • Source
    Human CD171, His Tag(CD1-H52H4) is expressed from human 293 cells (HEK293). It contains AA Ile 20 - Glu 1120 (Accession # P32004-1).
    Predicted N-terminus: Ile 20
  • Molecular Characterization
    CD171 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 125.1 kDa. The protein migrates as 160-200 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
CD171 SDS-PAGE

Human CD171, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
CD171 MALS images

The purity of Human CD171, His Tag (Cat. No. CD1-H52H4) is more than 90% and the molecular weight of this protein is around 208-248 kDa verified by SEC-MALS.

  • Background
    L1CAM is a cell adhesion molecule of the immunoglobulin superfamily which was originally discovered as a major player in the development of the nervous system. L1CAM was demonstrated to have prognostic value in different cancers and to be a promising target for anti-cancer therapy.
  • Clinical and Translational Updates

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