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Your Position: Start > Protein > LIV-1 > LV1-H5255

Human LIV-1 / SLC39A6 Protein, Fc Tag, low endotoxin

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  • Synonym
    SLC39A6,LIV-1,ZIP6,Zinc transporter ZIP6,ZIP-6
  • Quelle
    Human LIV-1, Fc Tag (LV1-H5255) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Trp 325 (Accession # Q13433-1).
    Predicted N-terminus: Phe 29
  • Molekulare Charakterisierung
    Online(Phe 29 - Trp 325) Q13433-1

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 60.1 kDa. The protein migrates as 70-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 0.05 EU per μg by the LAL method.
  • Reinheit

    >95% as determined by SDS-PAGE.

  • Rezeptur

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Rekonstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Lagerung

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human LIV-1, Fc Tag (Cat. No. LV1-H5255) SDS-PAGE gel

Human LIV-1, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA
Human LIV-1, Fc TagHuman LIV-1, Fc Tag (Cat. No. LV1-H5255) ELISA bioactivity

Immobilized Human LIV-1, Fc Tag (Cat. No. LV1-H5255) at 1 μg/mL (100 μL/well) can bind Anti-LIV-1 Antibody, Human IgG1 with a linear range of 0.6-5 ng/mL (QC tested).

  • Hintergrund
    LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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  • Number of Drugs in Clinical Trials:2 Details
  • Latest Research Phase:Phase 2 Clinical

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