Acrobiosystems for English
icon_bulk_orderAnfrage Sammelbestellung/Schnellbestellung
user
  1. Übersicht
  2. Mein Profil
  3. Meine Adresse
  4. Meine Bestellungen
  5. Acro-Mitgliedschaft
Login Registrieren
Promotion
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2
0
Es befinden sich keine Waren im Warenkorb !
Mein Warenkorb|Check Out
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Start > GAS6

GAS6

Brief Information

Name:Growth arrest-specific protein 6
Target Synonym:GAS6,AXLLG,Growth Arrest Specific 6,AXL Receptor Tyrosine Kinase Ligand,AXL Stimulatory Factor,Growth Arrest-Specific Protein 6,GAS-6,AXSF,FLJ34709,DKFZp666G247
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 3 Clinical

Product ListCompare or Buy

Product> Filter Results
Nach Produktstatus:
Nach Produktkategorie :
Nach Arten:
Nach Markierungen:
Nach Konjugaten:
Kat. Nr. Arten Produktbeschreibung Struktur Reinheit Merkmal
GA6-H5246 Human Human GAS6 (49-678) Protein, His Tag
GA6-H5246-structure
GA6-H5246-sds
GA6-H5247 Human Human GAS6 (471-678) Protein, His Tag (MALS verified)
GA6-H5247-structure
GA6-H5247-sds
GA6-H5249 Human Human GAS6 (279-678) Protein, His Tag (MALS verified)
GA6-H5249-structure
GA6-H5249-sds
ACRO Quality

Part of Bioactivity data

GA6-H5246-SPR
GAS6 SPR

Human Axl, Fc Tag (Cat. No. AXL-H5253) captured on Protein A Chip can bind Human GAS6 Protein, His Tag (Cat. No. GA6-H5246) with an affinity constant of 38.6 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol
GA6-H5249-SPR
GAS6 SPR

Human Axl, His Tag (Cat. No. AXL-H5226) immobilized on CM5 Chip can bind Human GAS6, His Tag (Cat. No. GA6-H5249) with an affinity constant of 3.4 nM as determined in SPR assay (Biacore 8K) (Routinely tested).

Protocol

Synonym Name

GAS6,GAS-6,AXLLG

Background

GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Batiraxcept AVB-500; Aravive S-6; AVB-S6-500; Ruga-S6; 3D-229; 3D229 Phase 3 Clinical Aravive Inc Ovarian Neoplasms; Solid tumours; Glomerulonephritis, IGA; Carcinoma, Renal Cell; Neoplasms; Pancreatic Neoplasms; Carcinoma, Transitional Cell; Carcinoma, Ovarian Epithelial; Peritoneal Neoplasms; Uterine Neoplasms; Fallopian Tube Neoplasms Details
Batiraxcept AVB-500; Aravive S-6; AVB-S6-500; Ruga-S6; 3D-229; 3D229 Phase 3 Clinical Aravive Inc Ovarian Neoplasms; Solid tumours; Glomerulonephritis, IGA; Carcinoma, Renal Cell; Neoplasms; Pancreatic Neoplasms; Carcinoma, Transitional Cell; Carcinoma, Ovarian Epithelial; Peritoneal Neoplasms; Uterine Neoplasms; Fallopian Tube Neoplasms Details

This web search service is supported by Google Inc.

totop
Call us
Call us

Germany+49 800 0826645

United Kingdom+44 808 281 3436

Netherlands+31 800 0224992

Switzerland+41 800 040 012

France+33 800 90 78 85

Sweden+46 20 12 76 94

Denmark+45 80 83 07 62

Belgium+32 800 27 125

Email
E-Mail
order@acrobiosystems.com
Fax
Fax
+1 888-377-6111
Address
Address
Lichtstrasse 35,4056 Basel, Switzerland
linkedin twitter facebook youtube

Nachricht schicken

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap