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MMAE

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MME-PLS104 Mouse HRP conjugated Anti-MMAE Antibody, mAb
MME-PLS104-sds
MME-M5252 Mouse Mouse Anti-MMAE Antibody, Mouse IgG1 (MALS verified)
MME-M5252-sds
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Part of Bioactivity data

MME-M5252-ELISA
MMAE ELISA

Immobilized Disitamab Vedotin (RC48) at 0.2 μg/mL (100 μL/well) can bind Mouse Anti-MMAE Antibody, Mouse IgG1 (Cat. No. MME-M5252) with a linear range of 0.1-2 ng/mL (QC tested).

Protocol
MME-M5252-MALS-HPLC
MMAE MALS images

The purity of Mouse Anti-MMAE Antibody, Mouse IgG1 (Cat. No. MME-M5252) is more than 90% and the molecular weight of this protein is around 134-163 kDa verified by SEC-MALS.

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Background

Monomethyl auristatin E (MMAE) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. Anti-MMAE antibody is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: PK, PD, Immunoassay and ELISA.

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