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Expression analysis of human CEACAM5 on HEK293/Human CEACAM5 Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human CEACAM5 Stable Cell Line or negative control cell using PE-labeled anti-human CEACAM5 antibody.
Anti-CEACAM-5 (labetuzumab) Antibody, Human IgG1 captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Biotinylated Human CEACAM-5, His,Avitag (Cat. No. CE5-H82E0) with an affinity constant of 12.1 nM as determined in a SPR assay (Biacore T200) (Routinely tested).
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Tusamitamab Ravtansine | SAR-408701; IBI-126 | Phase 3 Clinical | Immunogen Inc | Stomach Neoplasms; Esophageal Neoplasms; Pancreatic Neoplasms; Neoplasms; Breast Neoplasms; Lung Neoplasms; Metastatic breast cancer; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma | Details |
SGM-101 | SGM-101 | Phase 3 Clinical | Surgimab Sas | Intestinal Neoplasms; Rectal Neoplasms; Gastrointestinal Diseases; Colonic Neoplasms; Pancreatic Neoplasms; Brain Diseases; Brain Neoplasms; Colorectal Neoplasms; Colonic Diseases; Brain metastases; Gastrointestinal Neoplasms; Intestinal Diseases | Details |
Cancer vaccine (BN ImmunoTherapeutics/National Cancer Institute) | CVAC-301; CV-301 | Phase 2 Clinical | Therion Biologics | Ovarian Neoplasms; Cystadenocarcinoma; Intestinal Neoplasms; Solid tumours; Pancreatic Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Prostatic Neoplasms; Colorectal Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Neoplasm Metastasis; Melanoma | Details |
NEO-201 | NEO-201 | Phase 2 Clinical | Precision Biologics Inc, National Cancer Institute | Squamous Cell Carcinoma of Head and Neck; Uterine Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms | Details |
Anti-CEA CAR T cell therapy (Shanghai GeneChem) | Phase 2 Clinical | Shanghai Genechem Co Ltd, The First Affiliated Hospital of Air Force Medical University | Liver Neoplasms; Colorectal Neoplasms | Details | |
LM-24C5 | LM-24C5 | Phase 2 Clinical | LaNova Medicines Ltd | Solid tumours; Neoplasms | Details |
MFE-23-CD3z T cell therapy (Cancer Research Technology) | Phase 1 Clinical | Cancer Research Technology | Neoplasms | Details | |
Cergutuzumab amunaleukin | RG-7813; RO-6895882 | Phase 1 Clinical | F. Hoffmann-La Roche Ltd | Solid tumours; Neoplasms | Details |
EBC-129 | EBC-129; EBC129 | Phase 1 Clinical | Experimental Drug Development Centre | Solid tumours | Details |
M-9140 | M-9140; M9140 | Phase 1 Clinical | Merck KGaA, Darmstadt, Germany | Solid tumours; Colorectal Neoplasms | Details |
Tusamitamab Ravtansine | SAR-408701; IBI-126 | Phase 3 Clinical | Immunogen Inc | Stomach Neoplasms; Esophageal Neoplasms; Pancreatic Neoplasms; Neoplasms; Breast Neoplasms; Lung Neoplasms; Metastatic breast cancer; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma | Details |
SGM-101 | SGM-101 | Phase 3 Clinical | Surgimab Sas | Intestinal Neoplasms; Rectal Neoplasms; Gastrointestinal Diseases; Colonic Neoplasms; Pancreatic Neoplasms; Brain Diseases; Brain Neoplasms; Colorectal Neoplasms; Colonic Diseases; Brain metastases; Gastrointestinal Neoplasms; Intestinal Diseases | Details |
Cancer vaccine (BN ImmunoTherapeutics/National Cancer Institute) | CVAC-301; CV-301 | Phase 2 Clinical | Therion Biologics | Ovarian Neoplasms; Cystadenocarcinoma; Intestinal Neoplasms; Solid tumours; Pancreatic Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Prostatic Neoplasms; Colorectal Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Neoplasm Metastasis; Melanoma | Details |
NEO-201 | NEO-201 | Phase 2 Clinical | Precision Biologics Inc, National Cancer Institute | Squamous Cell Carcinoma of Head and Neck; Uterine Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms | Details |
Anti-CEA CAR T cell therapy (Shanghai GeneChem) | Phase 2 Clinical | Shanghai Genechem Co Ltd, The First Affiliated Hospital of Air Force Medical University | Liver Neoplasms; Colorectal Neoplasms | Details | |
LM-24C5 | LM-24C5 | Phase 2 Clinical | LaNova Medicines Ltd | Solid tumours; Neoplasms | Details |
MFE-23-CD3z T cell therapy (Cancer Research Technology) | Phase 1 Clinical | Cancer Research Technology | Neoplasms | Details | |
Cergutuzumab amunaleukin | RG-7813; RO-6895882 | Phase 1 Clinical | F. Hoffmann-La Roche Ltd | Solid tumours; Neoplasms | Details |
EBC-129 | EBC-129; EBC129 | Phase 1 Clinical | Experimental Drug Development Centre | Solid tumours | Details |
M-9140 | M-9140; M9140 | Phase 1 Clinical | Merck KGaA, Darmstadt, Germany | Solid tumours; Colorectal Neoplasms | Details |
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