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Biotinylated Human Insulin R (28-944) Protein, His,Avitag (Cat. No. INR-H82E6) immobilized on SA Chip can bind Insulin with an affinity constant of 35.6 nM as determined in a SPR assay (Biacore 8K) (QC tested).
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Insulin biosimilar (Sedico) | Approved | Sedico | Insulin H bio R | Egypt | Diabetes Mellitus | Sedico | 2013-02-01 | Diabetes Mellitus | Details | |
| Oral insulin (Generex Biotechnology) | Approved | Generex Biotechnology Corp | Oralin, Oralgen, Oral-lyn, Recosulin | Ecuador | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | null | 2005-01-01 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Details | |
| Insul 30/70 biosimilar (Popular Pharmaceuticals) | Approved | Popular Pharmaceuticals | Insul 30-70 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestational | Details | |||||
| Isophane Protamine Recombinant Human Insulin biosimilar (Popular Pharmaceuticals) | Approved | Popular Pharmaceuticals | Insulin N | Bangladesh | Diabetes Mellitus | Popular Pharmaceuticals | 2013-01-01 | Diabetes Mellitus | Details | |
| Isophane Protamine Human Insulin（30R）(Novo Nordisk ) | Approved | Novo Nordisk A/S | 诺和灵30R | Mainland China | Diabetes Mellitus | Novo Nordisk A/S | 1999-07-28 | Diabetes Mellitus | Details | |
| Human insulin biosimilar (Square Pharmaceuticals) | Approved | Square Pharmaceuticals Ltd | Ansulin | Bangladesh | Diabetes Mellitus | Square Pharmaceuticals Ltd | 2013-01-01 | Diabetes Mellitus | Details | |
| Isophane Protamine Recombinant Human Insulin Injection (Shenzhen Kexing Biotech) | Approved | Shenzhen Kexing Biological Engineering Co Ltd | 苏泌啉恩 | Mainland China | Diabetes Mellitus | Shenzhen Kexing Biological Engineering Co Ltd | 2003-02-24 | Diabetes Mellitus | Details | |
| Insulin glargine biosimilar (Getz Pharma) | Approved | Getz Pharma | Basagine | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Details | |||||
| Insulin glargine biosimilar (Biocon) | MYL-1501D | Approved | Fujifilm Corp, Biocon Biopharmaceuticals, Mylan Nv | Semglee, Basalog | India | Diabetes Mellitus | null | 2009-01-01 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| Isophane Protamine Human Insulin（40R）(Tonghua Dongbao) | Approved | Tonghua Dongbao Pharmaceutical Co Ltd | Diabetes Mellitus | Details | ||||||
| Recombinant lispro insulin biosimilar (Gan & Lee) | Approved | Gan & Lee Pharmaceuticals | Prandilin, 速秀霖 | Mainland China | Diabetes Mellitus | Gan & Lee Pharmaceuticals | 2006-01-19 | Diabetes Mellitus | Details | |
| Insulin lispro protamine(25R) (Lilly ) | Approved | Lilly Suzhou Pharmaceutical Co Ltd | Diabetes Mellitus | Details | ||||||
| Recombinant human insulin (SciGen) | Approved | Generex Biotechnology Corp | Recojet | India | Diabetes Mellitus | null | 2004-12-01 | Diabetes Mellitus | Details | |
| Recombinant human insulin (Shenzhen Kexing Biotech) | Approved | Shenzhen Kexing Biological Engineering Co Ltd | 苏泌啉, Su Bi Lin | Mainland China | Diabetes Mellitus | Shenzhen Kexing Biological Engineering Co Ltd | 2002-06-10 | Diabetes Mellitus | Details | |
| Imeglimin hydrochloride | EMD-387008; PXL-008 | Approved | Merck KGaA, Darmstadt, Germany | Twymeeg, ツイミーグ | Japan | Diabetes Mellitus, Type 2 | Poxel Sa, Sumitomo Dainippon Pharma Co Ltd | 2021-06-23 | Diabetes Mellitus, Type 2; Heart Diseases; Hepatic Insufficiency | Details |
| Recombinant human insulin (Hefei Tianmai Biotechnology) | Approved | Hefei Tianmai Biotechnology Development Co Ltd | Mainland China | Diabetes Mellitus | Hefei Tianmai Biotechnology Development Co Ltd | 2018-04-28 | Diabetes Mellitus | Details | ||
| Rinsulin NPH (Geropharm) | Approved | Geropharm | Rinsulin NPH | Russian Federation | Diabetes Mellitus | Geropharm | 2012-10-01 | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | |
| Isophane Protamine Recombinant Human Insulin (Hefei Tianmai Biotechnology) | Approved | Hefei Tianmai Biotechnology Development Co Ltd | Mainland China | Diabetes Mellitus | Hefei Tianmai Biotechnology Development Co Ltd | 2019-09-05 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | ||
| Insulin aspart biosimilar (Zhuhai United Laboratories) | Approved | Zhuhai United Laboratories Co Ltd | 联邦优倍灵, Ublin | Mainland China | Diabetes Mellitus | Zhuhai United Laboratories Co Ltd | 2021-07-12 | Diabetes Mellitus | Details | |
| Insulin glargine biosimilar (Wanbang Biochemical) | Approved | Wanbang Biopharmaceuticals Co Ltd | Mainland China | Diabetes Mellitus | Wanbang Biopharmaceuticals Co Ltd | 2022-08-30 | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | ||
| Isophane Protamine Human Insulin(30R)(Lilly) | Approved | Eli Lilly And Company | Mainland China | Diabetes Mellitus | Eli Lilly And Company | Diabetes Mellitus | Details | |||
| Insulin glulisine | HMR-1964 | Approved | Sanofi | 艾倍得, Apidra | United States | Diabetes Mellitus | Sanofi-Aventis U.S. Llc | 2004-04-16 | Diabetes Mellitus, Type 1; Leukemia; Diabetes Mellitus, Type 2; Heart Failure; Myocardial Infarction; Down Syndrome; Hyperglycemia; Cardiovascular Diseases; Cognitive Dysfunction; Alzheimer Disease; Diabetes Mellitus; Respiratory Insufficiency | Details |
| Insulin glargine biosimilar (Incepta Pharmaceuticals) | Approved | Incepta Pharmaceuticals Ltd | Bangladesh | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Incepta Pharmaceuticals Ltd | 2012-08-01 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Details | ||
| Insulin lispro biosimilar (Wanbang Biopharma) | Approved | Wanbang Biopharmaceuticals Co Ltd | Mainland China | Diabetes Mellitus | Wanbang Biopharmaceuticals Co Ltd | 2022-01-25 | Diabetes Mellitus | Details | ||
| Insulin human | HR-1799 | Approved | Sanofi Deutschland | Insulin Human Winthrop | EU | Diabetes Mellitus; Diabetic Coma; Diabetic Ketoacidosis | Sanofi-Aventis Deutschland Gmbh | 1997-02-21 | Diabetic Coma; Diabetic Ketoacidosis; Glaucoma; Diabetes Mellitus | Details |
| 30/70 Mixture Recombinant Human Insulin(Tonghua Dongbao Pharmaceutical) | Approved | Tonghua Dongbao Pharmaceutical Co Ltd | 甘舒霖30R | Mainland China | Diabetes Mellitus | Tonghua Dongbao Pharmaceutical Co Ltd | 2002-05-18 | Diabetes Mellitus | Details | |
| Insulin Aspart 50(Tonghua Dongbao Pharmaceutical) | Approved | Tonghua Dongbao Pharmaceutical Co Ltd | Mainland China | Diabetes Mellitus | Tonghua Dongbao Pharmaceutical Co Ltd | 2022-11-08 | Diabetes Mellitus | Details | ||
| Insulin aspart biosimilar (Tonghua Dongbao Pharmaceutical) | Approved | Tonghua Dongbao Pharmaceutical Co Ltd | Mainland China | Diabetes Mellitus | Tonghua Dongbao Pharmaceutical Co Ltd | 2021-10-19 | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | ||
| Insulin Aspart 50 biosimilar (Jilin Huisheng Biological) | Approved | Jilin Huisheng Biopharmaceutical Co Ltd | Mainland China | Diabetes Mellitus | Jilin Huisheng Biopharmaceutical Co Ltd | 2023-12-26 | Diabetes Mellitus | Details | ||
| Recombinant insulin (Horizon Pharma/Ibatech) | Approved | Savient Pharmaceuticals Inc | Poland | Diabetes Mellitus, Type 1 | null | 2002-07-01 | Diabetes Mellitus, Type 1 | Details | ||
| Recombinant human insulin (HEC Pharm) | Approved | Yichang Hec Changjiang Pharmaceutical Co Ltd | Mainland China | Diabetes Mellitus | Yichang Hec Changjiang Pharmaceutical Co Ltd | 2020-06-05 | Diabetes Mellitus | Details | ||
| Insulin degludec | NN-1250; Insulin-454 | Approved | Novo Nordisk A/S | 诺和达, Tresiba | Japan | Diabetes Mellitus, Type 2; Diabetes Mellitus; Diabetes Mellitus, Type 1 | Novo Nordisk A/S | 2012-09-28 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| Human insulin biosimilar (MJ Biopharm) | Approved | Mj Biopharm Pvt | Biosulin | India | Diabetes Mellitus | Mj Biopharm Pvt | 2005-12-01 | Diabetes Mellitus | Details | |
| Insulin glargine | U-300; Gla-100; Gla-300; Hoe-901; Hoe-71GT; HOE901-U300 | Approved | Sanofi | 来得时, Lantus, Toujeo, Lantus XR, Optisulin | United States | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Sanofi-Aventis U.S. Llc | 2000-04-20 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Atherosclerosis; Hyperglycemia; Hypercholesterolemia; Hypertension; Coronary Disease; Cardiovascular Diseases; Diabetes Mellitus | Details |
| Isophane Protamine Recombinant Human Insulin (BIOTON） | Approved | Bioton Sa | Mainland China | Diabetes Mellitus | Bioton Sa | 2013-03-29 | Diabetes Mellitus | Details | ||
| Insulin Aspart 30 (Yichang Hec Changjiang Pharmaceutical) | Approved | Yichang Hec Changjiang Pharmaceutical Co Ltd | Mainland China | Diabetes Mellitus | Yichang Hec Changjiang Pharmaceutical Co Ltd | 2022-11-01 | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | ||
| Insulin Glargine biosimilar (Liaoning Bo'Ao Bio-Pharmaceutical) | Approved | Liaoning Bo'Ao Bio-Pharmaceutical Co Ltd | Mainland China | Diabetes Mellitus | Liaoning Bo'Ao Bio-Pharmaceutical Co Ltd | 2023-12-05 | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | ||
| Isophane Protamine Human Insulin（30R）(Hec Pharm) | Approved | Hec Pharm Co Ltd | 诺和灵30R | Mainland China | Diabetes Mellitus | Hec Pharm Co Ltd | 2023-09-19 | Diabetes Mellitus | Details | |
| 50/50 Mixture Recombinant Human Insulin（Tonghua Dongbao Pharmaceutical） | Approved | Tonghua Dongbao Pharmaceutical Co Ltd | 甘舒霖50R | Mainland China | Diabetes Mellitus | Tonghua Dongbao Pharmaceutical Co Ltd | 2008-02-04 | Diabetes Mellitus | Details | |
| Insulin biosimilars (Bioton) | Approved | Bioton Sa | Mainland China | Diabetes Mellitus | Bioton Sa | 2013-01-01 | Diabetes Mellitus | Details | ||
| Recombinant human insulin (Incepta) | Approved | Incepta Pharmaceuticals Ltd | Maxsulin | Bangladesh | Diabetes Mellitus | Incepta Pharmaceuticals Ltd | 2012-01-01 | Diabetes Mellitus | Details | |
| Insulin human (rDNA origin, Novo Nordisk) | NN-729 | Approved | Novo Nordisk A/S | Insulatard, Actraphane, Mixtard, Novolin R, 诺和灵R | United States | Diabetes Mellitus, Type 2 | Novo Nordisk Inc | 1991-06-25 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Smoking Cessation; Hyperglycemia; Cognitive Dysfunction; Alzheimer Disease; Parkinson Disease; Alcoholism; Pulmonary Disease, Chronic Obstructive; Lymphoma; Diabetes Mellitus | Details |
| Insulin aspart | NN-1218; INA-X14; Insulin X14 | Approved | Novo Nordisk A/S | Novolog, NovoRapid, NovoLog FlexPen, NovoMix, Fiasp, 诺和锐, NovoRapid/NovoLog | EU | Diabetes Mellitus | Novo Nordisk A/S | 1999-09-07 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Atherosclerosis; Delirium; Hypercholesterolemia; Hypertension; Postoperative Cognitive Complications; Coronary Disease; Alzheimer Disease; Cognitive Dysfunction; Cardiovascular Diseases; Diabetes Mellitus | Details |
| Recombinant insulin aspart biosimilar (Yichang Hec Changjiang Pharmaceutical) | Approved | Yichang Hec Changjiang Pharmaceutical Co Ltd | Mainland China | Diabetes Mellitus | Yichang Hec Changjiang Pharmaceutical Co Ltd | 2022-10-11 | Diabetes Mellitus | Details | ||
| Recombinant human insulin (Tonghua Dongbao Pharmaceutical) | Approved | Tonghua Dongbao Pharmaceutical Co Ltd | 甘舒霖, 甘舒霖R | Mainland China | Diabetes Mellitus | Tonghua Dongbao Pharmaceutical Co Ltd | 1998-01-01 | Diabetes Mellitus | Details | |
| Recombinant Human Insulin (Wanbang Pharma) | Approved | Wanbang Biopharmaceuticals Co Ltd | Mainland China | Diabetes Mellitus | Wanbang Biopharmaceuticals Co Ltd | 2003-08-29 | Diabetes Mellitus | Details | ||
| Insulin human (rDNA) biosimilar (Baxter) | Approved | Baxter International Inc | Inpremzia, Myxredlin | United States | Diabetes Mellitus | Baxter Healthcare Corp | 2019-06-20 | Diabetes Mellitus | Details | |
| Mixed Protamine Human Insulin（40R）(Tonghua Dongbao Pharmaceutical) | Approved | Tonghua Dongbao Pharmaceutical Co Ltd | 甘舒霖N | Mainland China | Diabetes Mellitus | Tonghua Dongbao Pharmaceutical Co Ltd | 1999-01-01 | Diabetes Mellitus | Details | |
| Insulin degludec/Liraglutide | NN-9068 | Approved | Novo Nordisk A/S | Xultophy, iDegLira | EU | Diabetes Mellitus, Type 2 | Novo Nordisk A/S | 2014-09-18 | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| Recombinant insulin glargine (Gan & Lee) | GL-GLA | Approved | Gan & Lee Biotech | 长秀霖, Basalin | Mainland China | Diabetes Mellitus | Gan & Lee Pharmaceuticals | 2005-05-10 | Diabetes Mellitus, Type 1; Diabetes Mellitus | Details |
| Isophane Protamine Human Insulin（50R）(Novo Nordisk ) | Approved | Novo Nordisk A/S | 诺和灵50R | Mainland China | Diabetes Mellitus | Novo Nordisk (China)Pharmaceuticals Co Ltd | 2019-11-27 | Diabetes Mellitus | Details | |
| Insulin glargine biosimilar (Lilly/Boehringer Ingelheim) | LY-2963016; LY2963016-U-100; LY2963016-U-200 | Approved | Boehringer Ingelheim Gmbh, Eli Lilly And Company | Abasria, Basaglar, Abasaglar, Rezvoglar | EU | Diabetes Mellitus | Eli Lilly Nederland BV | 2014-09-09 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Hyperglycemia; Renal Insufficiency, Chronic; Diabetes Mellitus | Details |
| Insulin Aspart 30(onghua Dongbao Pharmaceutical) | Approved | Tonghua Dongbao Pharmaceutical Co Ltd | Mainland China | Diabetes Mellitus | Tonghua Dongbao Pharmaceutical Co Ltd | 2022-11-08 | Diabetes Mellitus | Details | ||
| Insulin human(Organon France) | Approved | Organon France | EU | Diabetes Mellitus | Organon France | 1999-11-03 | Diabetes Mellitus | Details | ||
| Insulin biosimilar (Wockhardt) | Approved | Wockhardt Ltd | Wosulin Pen Royale, Wosulin, Wosulin®-R, Wosulin Pen | India | Diabetes Mellitus, Type 1 | Wockhardt Ltd | 2003-10-01 | Diabetes Mellitus, Type 1; Diabetes Mellitus | Details | |
| Recombinant human insulin (United Laboratories International Holdings) | Approved | Zhongshan Branch of Zhuhai United Laboratories Co Ltd | 优思灵, Uslin, 优思灵R | Mainland China | Diabetes Mellitus | Zhongshan Branch of Zhuhai United Laboratories Co Ltd | 2009-11-25 | Diabetes Mellitus | Details | |
| Insulin lispro | LY-900027; LY-275585; Lys-B28; Pro-B29; LYSPRO; LY-900014 | Approved | Eli Lilly And Company | Humalog, 优泌乐, Eglucent, Liprolog, Lyumjev, Liumjev | EU | Diabetes Mellitus | Eli Lilly Nederland BV | 1996-04-30 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Insulin Resistance; Diabetic Neuropathies; Diabetes Mellitus; Hyperlipidemias | Details |
| Insulin aspart biosimilar(Jilin Huisheng Biological) | Approved | Jilin Huisheng Biopharmaceutical Co Ltd | Mainland China | Diabetes Mellitus | Jilin Huisheng Biopharmaceutical Co Ltd | 2023-12-26 | Diabetes Mellitus | Details | ||
| Isophane Insulin | Approved | Wanbang Biopharmaceuticals Co Ltd | 万苏林 | Mainland China | Diabetes Mellitus | Wanbang Biopharmaceuticals Co Ltd | 1997-01-01 | Diabetes Mellitus | Details | |
| Insulin biosimilar (Harvest Moon Pharmaceuticals) | Approved | Harvest Moon | Diabetes Mellitus | Details | ||||||
| Insulin biosimilar (Julphar) | Approved | Julphar (Gulf Pharmaceutical Industries) | Julphar Insulin R | Tunisia | Diabetes Mellitus | Julphar (Gulf Pharmaceutical Industries) | 2013-10-01 | Diabetes Mellitus | Details | |
| Insulin lispro biosimilar (Sanofi) | SAR-342434 | Approved | Sanofi | Admelog | EU | Diabetes Mellitus | Sanofi Winthrop Industrie SA | 2017-07-18 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| Recombinant human insulin (Biocon) | Approved | Biocon Ltd | Insugen | India | Diabetes Mellitus | Biocon Ltd | 2004-11-10 | Diabetes Mellitus | Details | |
| Insulin detemir | NN-304 | Approved | Novo Nordisk A/S | 诺和平, Levemir | EU | Diabetes Mellitus | Novo Nordisk A/S | 2004-06-01 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Atherosclerosis; Hypercholesterolemia; Hypertension; Diabetes, Gestational; Coronary Disease; Alzheimer Disease; Cognitive Dysfunction; Cardiovascular Diseases; Diabetes Mellitus | Details |
| Insulin glargine biosimilar (Tonghua Dongbao Pharmaceutical) | Approved | Tonghua Dongbao Pharmaceutical Co Ltd | 长舒霖 | Mainland China | Diabetes Mellitus | Tonghua Dongbao Pharmaceutical Co Ltd | 2019-12-06 | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | |
| Insulin aspart biosimilar (Biocon/Mylan) | MYL-1601D | Approved | Biocon Ltd | EU | Diabetes Mellitus | Biosimilar Collaborations Ireland Ltd | 2021-02-05 | Diabetes Mellitus | Details | |
| Insulin glargine biosimilar (Zhuhai United) | Approved | Zhuhai United Laboratories Co Ltd | Mainland China | Diabetes Mellitus | Zhuhai United Laboratories Co Ltd | 2016-12-23 | Diabetes Mellitus | Details | ||
| Insulin degludec/Insulin aspart | NN-1045; NN-5401; NN-1250/Insulin aspart | Approved | Novo Nordisk A/S | Ryzodeg, 诺和佳 | Japan | Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Novo Nordisk A/S | 2012-12-25 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| Isophane Protamine Human Insulin（50R）(Zhuhai United Laboratories ) | Approved | Zhongshan Branch of Zhuhai United Laboratories Co Ltd | 诺和灵50R | Mainland China | Diabetes Mellitus | Zhongshan Branch of Zhuhai United Laboratories Co Ltd | 2010-12-31 | Diabetes Mellitus | Details | |
| Insulin aspart biosimilar (Sanofi) | SAR-341402; SAR-Asp | Approved | Sanofi | Truvelog | EU | Diabetes Mellitus | Sanofi Winthrop Industrie SA | 2020-06-25 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| Insulin aspart biosimilar (Gan & Lee) | GL-ASP | Approved | Gan & Lee Biotech | Rapilin®30, Rapilin30, 锐秀霖30 | Mainland China | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Gan & Lee Biotech | 2020-06-05 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| Insulin human (rDNA origin, Lilly) | S-3300; LY-041001; U-500R | Approved | Eli Lilly And Company | Humulin R Kwikpen, Humulin, Humulin R, 优泌淋R, Humulin R Pen | United States | Diabetes Mellitus, Type 2 | Eli Lilly And Company | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Brain Neoplasms; Alzheimer Disease; Cognitive Dysfunction; Intracranial Aneurysm; Diabetes Mellitus | Details | |
| Insulin Aspart 30 biosimilar (Jilin Huisheng Biological) | Approved | Jilin Huisheng Biopharmaceutical Co Ltd | Mainland China | Diabetes Mellitus | Jilin Huisheng Biopharmaceutical Co Ltd | 2023-12-26 | Diabetes Mellitus | Details | ||
| Ceritinib | LDK-378; NVP-LDK378; NVP-LDK378-NX | Approved | Novartis Pharma Ag | 赞可达, Zykadia | EU | Carcinoma, Non-Small-Cell Lung | Novartis Europharm Ltd | 2014-04-29 | Colorectal Neoplasms; Melanoma; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Thyroid Neoplasms; Brain metastases; Esophageal adenocarcinoma; Granuloma, Plasma Cell; Lymphoma, Large-Cell, Anaplastic; Hematologic Neoplasms; Hepatic Insufficiency; Cholangiocarcinoma; Pancreatic Neoplasms; Thyroid Carcinoma, Anaplastic; Neoplasms; Glioblastoma; Stomach Neoplasms | Details |
| Rosinsulin | Approved | Medsintez | Diabetes Mellitus | Details | ||||||
| Insulin aspart biosimilar (Hisun Pharma) | Approved | Zhejiang Hisun Pharmaceutical Co Ltd | Mainland China | Diabetes Mellitus | Zhejiang Hisun Pharmaceutical Co Ltd | 2021-09-13 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | ||
| Insulin glargine biosimilar (Wockhardt) | Approved | Wockhardt Bio Ag | Glaritus, Glaritus Cart, Glaritus DispoPen | India | Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Wockhardt Ltd | 2013-01-01 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | |
| Insulin glargine biosimilar (LG Life Sciences) | Approved | Lg Life Sciences Ltd | Basugine | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Details | |||||
| Isophane Protamine Recombinant Human Insulin(Novo Nordisk) | Approved | Novo Nordisk (China)Pharmaceuticals Co Ltd | 诺和灵N | Mainland China | Diabetes Mellitus | Novo Nordisk (China)Pharmaceuticals Co Ltd | 2016-06-16 | Diabetes Mellitus | Details | |
| Insulin biosimilar (Popular Pharmaceuticals) | Approved | Popular Pharmaceuticals | Insul R | Bangladesh | Diabetes Mellitus | Popular Pharmaceuticals | 2013-01-01 | Diabetes Mellitus | Details | |
| Insulin glargine biosimilar(Shandong New Time Pharmaceutical) | Approved | Lunan Pharmaceutical Group Co | Mainland China | Diabetes Mellitus | Shandong New Time Pharmaceutical Co Ltd | 2022-05-10 | Diabetes Mellitus | Details | ||
| Isophane Insulin(Polish Society of Diabetology) | Approved | Polish Society of Diabetology | Diabetes Mellitus | Details | ||||||
| Lixisenatide/Insulin glargine | HOE-901/AVE-0010 | Approved | Sanofi | Soliqua, iGlarLixi, Suliqua | United States | Diabetes Mellitus, Type 2 | Sanofi-Aventis U.S. Llc | 2016-11-21 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Details |
| Insulin Aspart 50 | Approved | Novo Nordisk A/S | 诺和锐50 | Mainland China | Diabetes Mellitus | Novo Nordisk A/S | 2012-02-10 | Diabetes Mellitus | Details | |
| Insulin lispro protamine biosimilar(25R) (Gan & Lee) | Approved | Gan & Lee Biotech | Prandilin25, 速秀霖25 | Mainland China | Diabetes Mellitus | Gan & Lee Pharmaceuticals | 2014-05-09 | Diabetes Mellitus | Details | |
| Isophane Protamine Human Insulin（30R）(Gan & Lee ) | Approved | Gan & Lee Pharmaceuticals | Mainland China | Diabetes Mellitus | Gan & Lee Pharmaceuticals | 2021-05-19 | Diabetes Mellitus | Details | ||
| Insulin human (inhalation powder) | SAR-439065 | Approved | Mannkind Corporation | Technosphere Insulin System, Afrezza, Afresa | United States | Diabetes Mellitus, Type 2 | Mannkind Corporation | 2014-06-27 | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Hyperglycemia; Asthma; Pulmonary Disease, Chronic Obstructive; Diabetes Mellitus | Details |
| Insulin Aspart 30 | Approved | Novo Nordisk A/S | 诺和锐30 | Mainland China | Diabetes Mellitus | Novo Nordisk A/S | 2009-09-30 | Diabetes Mellitus | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Recombinant insulin aspart biosimilar (Biogenomics) | Phase 3 Clinical | Biogenomics | Diabetes Mellitus, Type 2 | Details | |
| Human insulin biosimilar（Indonesia University） | Phase 2 Clinical | Indonesia University | Diabetes Mellitus | Details | |
| BC Combo U200 | Phase 1 Clinical | Adocia, Tonghua Dongbao Pharmaceutical Co Ltd | Diabetes Mellitus | Details | |
| Insulin degludec/Liraglutide(Huisheng Biopharmaceutical) | Phase 1 Clinical | Jilin Huisheng Biopharmaceutical Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Mixed Protamine Zinc Recombinant Insulin Lispro Injection(25R)（Tonghua Dongbao） | Phase 3 Clinical | Tonghua Dongbao Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | |
| Insulin Aspart (Beijing Sl Pharmaceutical) | Phase 3 Clinical | Beijing Sl Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Isophane Protamine Recombinant Human Insulin (Jilin Huisheng Biological ) | Phase 3 Clinical | Jilin Huisheng Biopharmaceutical Co Ltd | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | |
| Fast-acting human insulin (Adocia) | BioChaperone-222; Hinsbet-U500 | Phase 2 Clinical | Adocia | Diabetes Mellitus, Type 1; Metabolic Syndrome; Cognitive Dysfunction; Alzheimer Disease | Details |
| GZR-101 | GZR101 | Phase 2 Clinical | Gan & Lee Pharmaceuticals | Diabetes Mellitus | Details |
| Insulin enteric-coated(Tsinghua University) | Phase 3 Clinical | Tsinghua University, Beijing Representative Office Of Hong Kong Fushi Bioengineering Co Ltd | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Details | |
| Insulin degludec biosimilar (Zhongmei Huadong) | Phase 1 Clinical | Hangzhou Zhongmei Huadong Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| AB-101(Rezolute) | AB-101 | Phase 1 Clinical | Rezolute | Diabetes Mellitus, Type 1; Hepatitis B, Chronic | Details |
| Recombinant human insulin biosimilar (Rechon Life Sciences) | Phase 3 Clinical | Rechon Life Science Ab | Diabetes Mellitus, Type 1 | Details | |
| HR-17031 | HR17031 | Phase 2 Clinical | Jiangsu Hengrui Medicine Co Ltd | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| CB-4211 | CB-4211 | Phase 1 Clinical | Cohbar Inc | Non-alcoholic Fatty Liver Disease | Details |
| Pegylated recombinant human insulin (Chongqing Fujin Biomedical) | CA001 | Phase 1 Clinical | Chongqing Fujin Biological Medicine Co Ltd | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| Insulin Aspart 30 (Liaoning Bo'Ao Bio-Pharmaceutical) | Phase 1 Clinical | Liaoning Bo'Ao Bio-Pharmaceutical Co Ltd | Diabetes Mellitus | Details | |
| Insulin degludec/Liraglutide(Lianbang Biotech) | Phase 1 Clinical | Lianbang Biotechnology (Zhuhai Hengqin) Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Mixed Protamine Zinc Recombinant Insulin Lispro Injection(50R/25R)（Fosun Pharma） | Phase 1 Clinical | Fosun Holdings Ltd | Diabetes Mellitus, Type 2 | Details | |
| Insulin degludec/Insulin aspart（HEC） | Phase 3 Clinical | Dongguan City Hec Biological Medicine Res And Development Co Ltd, Guangdong Dongyangguang Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Insulin degludec/Insulin aspart（Jilin Huisheng） | NN-1045; NN-5401; NN-1250/Insulin aspart | Phase 3 Clinical | Jilin Huisheng Biopharmaceutical Co Ltd | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| Insulin lispro (Diasome Pharmaceuticals) | Phase 2 Clinical | Diasome Pharmaceuticals Inc | Diabetes Mellitus, Type 1 | Details | |
| Insulin degludec biosimilar (Jilin Jinsheng) | Phase 3 Clinical | Jilin Jinsheng Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | |
| Insulin degludec biosimilar (Zhuhai United) | Phase 3 Clinical | Zhuhai United Laboratories Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| INS-068 | INS-068 | Phase 3 Clinical | Shanghai Hengrui Pharmaceutical Co Ltd, Chengdu Suncadia Medicine Co Ltd, Jiangsu Hengrui Medicine Co Ltd | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| AKP-11 | AKP-11 | Phase 2 Clinical | Akaal Pharma | Psoriasis; Dermatitis, Atopic | Details |
| Dulaglutide/Basal insulin Fc | Phase 1 Clinical | Eli Lilly And Company | Diabetes Mellitus | Details | |
| Recombinant insulin lisargine(Hefei Tianmai Biotech) | Phase 3 Clinical | Hefei Tianmai Biotechnology Development Co Ltd | Diabetes Mellitus | Details | |
| NT-219 | NT-219; NT219 | Phase 2 Clinical | TyrNovo Ltd | Solid tumours; Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Neoplasm Metastasis | Details |
| Insulin aspart biosimilar (Kunpeng) | Phase 3 Clinical | Ningbo Kunpeng Biological Technology Co Ltd | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | |
| Insulin aspart biosimilar(Amphastar) | I-004 | Phase 3 Clinical | Amphastar Pharmaceuticals Inc | Details | |
| Ersodetug | XPA.15.247; XOMA-247; RZ358; RZ-358; XOMA-358 | Phase 2 Clinical | Xoma Corp | Congenital Hyperinsulinism; Hypoglycemia | Details |
| Insulin (Coremed) | Phase 1 Clinical | Coremed | Diabetes Mellitus | Details | |
| Protamine Recombinant Human Insulin (Gan & Lee Pharmaceuticals) | Phase 3 Clinical | Gan & Lee Pharmaceuticals | Diabetes Mellitus, Type 2 | Details | |
| GZR-4 | GZR4; GZR-4 | Phase 2 Clinical | Gan & Lee Pharmaceuticals | Diabetes Mellitus | Details |
| Oral insulin (Purede) | Clinical | Puredel | Diabetes Mellitus | Details | |
| Basal insulin Fc (Eli Lilly) | Phase 1 Clinical | Eli Lilly And Company | Diabetes Mellitus | Details | |
| NNC0363-0845 | Phase 1 Clinical | Novo Nordisk A/S | Diabetes Mellitus, Type 1 | Details | |
| Recombinant insulin glargine (Chongqing Fujin Biological Medicine) | Phase 3 Clinical | Chongqing Fujin Biological Medicine Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Insulin Glargine (Zhejiang Hisun Pharmaceutical) | HS004 | Phase 3 Clinical | Zhejiang Hisun Pharmaceutical Co Ltd | Diabetes Mellitus | Details |
| Insulin degludec/Insulin aspart (United Laboratories) | Phase 1 Clinical | Lianbang Biotechnology (Zhuhai Hengqin) Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Insulin icodec/Semaglutide | Phase 3 Clinical | Novo Nordisk A/S | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | |
| Insulin lispro protamine biosimilar(50R) (Gan & Lee) | Phase 1 Clinical | Gan & Lee Pharmaceuticals | Diabetes Mellitus | Details | |
| TOTUM•63 | TOTUM-63 | Phase 3 Clinical | Valbiotis | Diabetes Mellitus, Type 2 | Details |
| Isophane Protamine Recombinant Human Insulin (Pre-Mixed 30R) (Hec Pharm) | Phase 3 Clinical | Yichang Hec Changjiang Pharmaceutical Co Ltd | Diabetes Mellitus | Details | |
| Insulin biosimilar (Valin Technologies) | Van-101 | Phase 3 Clinical | Valin Technologies | Diabetes Mellitus | Details |
| Insulin detemir biosimilar (Tonghua Dongbao Pharmaceutical) | Phase 1 Clinical | Tonghua Dongbao Biotechnology Co Ltd | Diabetes Mellitus | Details | |
| Recombinant human insulin (Eastgate Biotech) | EGP-1214 | Clinical | Eastgate Biotech | Prediabetic State; Diabetes Mellitus, Type 2 | Details |
| NP-01 (Medesis Pharma SA) | NP01 | Phase 1 Clinical | Medesis Pharma Sa | Diabetes Mellitus, Type 2 | Details |
| scp776 | scp776 | Phase 2 Clinical | Silver Creek Pharmaceuticals Inc | Stroke | Details |
| Insulin degludec biosimilar (Tonghua Dongbao) | Phase 1 Clinical | Tonghua Dongbao Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Insulin oral (Diabetology) | DTY-001 | Phase 2 Clinical | Diabetology Ltd | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Details |
| Insulin lispro/Insulin glargine | THDB-0207 | Phase 1 Clinical | Adocia | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| Insulin tregopil (Biocon) | IN-105; NIN-058; HIM-2; GW-843362 | Phase 3 Clinical | Biocon Ltd | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Details |
| Insulin glargine（GeneSys Biologics） | GEN-1501 | Phase 1 Clinical | GeneSys Biologics Pvt Ltd | Diabetes Mellitus | Details |
| Insulin biosimilar (University of Montreal Health Centre) | Phase 1 Clinical | University Of Montreal Health Centre | Glaucoma | Details | |
| Insulin aspart(Chongqing Chenan) | Phase 1 Clinical | Chongqing Chenan Biopharmaceutical Co Ltd | Diabetes Mellitus | Details | |
| Insulin aspart (Jilin Jinsheng) | Phase 3 Clinical | Jilin Jinsheng Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | |
| Ultra fast-acting insulin (Adocia) | THDB-0206; THDB0206; BC-106-Insulin-Lispro; BC-222-Insulin-Lispro | Phase 3 Clinical | Adocia | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | Details |
| Recombinant human insulin (Zhejiang Hisun Pharmaceutical) | Phase 1 Clinical | Zhejiang Hisun Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Insulin degludec biosimilar（Zhuhai Jibaikang） | Phase 1 Clinical | Zhuhai Jibaikang Biological Tech Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Basal insulin acylated (Lilly) | Phase 1 Clinical | Eli Lilly And Company | Diabetes Mellitus | Details | |
| Insulin degludec biosimilar (Chenan Biopharmaceutical) | Phase 3 Clinical | Chongqing Chenan Biopharmaceutical Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Pramlintide/Insulin | ADO-09 | Phase 2 Clinical | Adocia | Diabetes Mellitus, Type 1 | Details |
| Insulin glargine biosimilar (Geropharm) | Phase 3 Clinical | Geropharm | Diabetes Mellitus, Type 1; Diabetes Mellitus | Details | |
| Insulin degludec biosimilar (Chia Tai-Tianqing) | Phase 3 Clinical | Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Insulin glargine biosimilar (Valin Technologies) | Phase 1 Clinical | Valin Technologies | Diabetes Mellitus | Details | |
| HR-011408 | HR011408; HR-011408 | Phase 1 Clinical | Jiangsu Hengrui Medicine Co Ltd | Diabetes Mellitus | Details |
| Insulin degludec biosimilar (Hisun Pharma) | Phase 1 Clinical | Zhejiang Hisun Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Insulin mouth rinse (EastGate Biotech) | Phase 3 Clinical | Genome Pharmaceuticals, Eastgate Biotech | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Alzheimer Disease | Details | |
| Semaglutide/Long-acting basal insulin analogue | NNC0148-0287sema | Phase 1 Clinical | Novo Nordisk A/S | Diabetes Mellitus, Type 2 | Details |
| Insulin human (Columbia University) | Phase 1 Clinical | Columbia University | Prediabetic State; Non-alcoholic Fatty Liver Disease; Insulin Resistance; Hyperinsulinism; Obesity | Details | |
| Insulin degludec/Insulin aspart（Hangzhou Zhongmei Huadong） | Phase 1 Clinical | Hangzhou Zhongmei Huadong Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Insulin degludec（Beijing ShuangLu Pharmaceutical） | Phase 1 Clinical | Beijing Sl Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Insulin lispro biosimilar (Geropharm) | Phase 3 Clinical | Geropharm | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | |
| Insulin aspart biosimilar (Geropharm) | GP-40071; GP-40081 | Phase 3 Clinical | Geropharm | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| Insulin degludec biosimilar (Nanjing Cellnuo) | Phase 1 Clinical | Nanjing Cellnuo Biopharmaceutical Co Ltd, Nanjing Sinor Biotechnology Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Recombinant human insulin (Nutrinia) | NTRA-9620 | Phase 3 Clinical | Nutrinia Inc | Diabetes Mellitus, Type 2 | Details |
| Human insulin (Ningbo Kunpeng) | Phase 1 Clinical | Ningbo Kunpeng Biological Technology Co Ltd | Diabetes Mellitus | Details | |
| Insulin degludec biosimilar (Hec) | RD15003 | Phase 3 Clinical | Dongguan City Hec Biological Medicine Res And Development Co Ltd | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| Insulin aspart biosimilar（Jiangsu HengRui） | INS-062; INS062 | Phase 1 Clinical | Jiangsu Hengrui Medicine Co Ltd | Diabetes Mellitus | Details |
| Insulin degludec/Insulin aspart (Chongqing Chenan Biopharma) | Phase 1 Clinical | Chongqing Chenan Biopharmaceutical Co Ltd | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | |
| Linsitinib | OSI-906; ASP-7487; OSI-906AA | Phase 3 Clinical | Astellas Pharma Inc, National Cancer Institute | Multiple Myeloma; Paraganglioma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Orbital Diseases; Eye Diseases; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Exophthalmos; Breast Neoplasms; Prostatic Neoplasms; Sarcoma, Ewing; Adrenocortical Carcinoma; Thyroid Diseases; Graves Ophthalmopathy; Endocrine System Diseases; Skin Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Pancreatic Neoplasms; Hashimoto Disease; Head and Neck Neoplasms; Ovarian Neoplasms; Carney Complex; Liver Neoplasms; Solid tumours; Chondrosarcoma | Details |
| Recombinant human insulin(Elgan) | ELGN-2112; ELGN-GI | Phase 3 Clinical | Elgan Pharma Ltd | Short Bowel Syndrome; Malabsorption Syndromes; Premature Birth | Details |
| Long-acting basal insulin analogue | LAI-287; NN-1436; NN-1956; OI-287GT; 148-0287-A; Insulin-287; NNC0148-0287 C; NNC-0148-0000-0287; Long-acting-insulin-287; Long-acting basal insulin analogue | Phase 3 Clinical | Novo Nordisk A/S | Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
| HDV Insulin (Diasome Pharmaceuticals) | Phase 2 Clinical | Eli Lilly And Company | Diabetes Mellitus, Type 1; Diabetes Mellitus | Details | |
| Recombinant human insulin(30/70) (Zhejiang Hisun Pharmaceutical) | Phase 3 Clinical | Zhejiang Hisun Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2 | Details | |
| Mixed Protamine Zinc Recombinant Insulin Lispro Injection(50R)（Tonghua Dongbao） | Phase 1 Clinical | Tonghua Dongbao Pharmaceutical Co Ltd | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details | |
| Insulin degludec biosimilar（Wanbang Pharma） | Phase 1 Clinical | Wanbang Biopharmaceuticals Co Ltd | Diabetes Mellitus, Type 2; Diabetes Mellitus | Details |
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