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IGFBP-1

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IG1-H52H3 Human Human IGFBP-1 Protein, His Tag (MALS verified)
IG1-H52H3-structure
IG1-H52H3-sds
ACRO Quality

Part of Bioactivity data

IG1-H52H3-MALS-HPLC
IGFBP-1 MALS images

The purity of Human IGFBP-1 Protein, His Tag (Cat. No. IG1-H52H3) is more than 90% and the molecular weight of this protein is around 22-32 kDa verified by SEC-MALS.

IG1-H52H3-ELISA
IGFBP-1 ELISA

Immobilized Human IGF-I, Fc Tag at 5 μg/mL (100 μL/well) can bind Human IGFBP-1 Protein, His Tag (Cat. No. IG1-H52H3) with a linear range of 0.01-0.156 μg/mL (QC tested).

Protocol

Synonym Name

IGFBP1,PP12,IBP1

Background

Insulin-like growth factor-binding protein 1 (IGFBP1) is also known as placental protein 12 (PP12), which contains oneIGFBP N-terminal domain and one thyroglobulin type-1 domain. IGFBP1 can bindd both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of IGFBP1 can prolongd the half-life of the IGFs and alterd their interaction with cell surface receptors. Furthermore, IGFBP1 can promote cell migration. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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