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Kat. Nr. | Arten | Produktbeschreibung | Struktur | Reinheit | Merkmal |
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AK1-H5283 | Human | Human Akt1 Protein, His,Strep II Tag | ![]() |
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Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
---|---|---|---|---|---|---|---|---|---|---|
Capivasertib | AZD-5363 | Approved | Astex Pharmaceuticals Inc, Cancer Research Technology, The Institute Of Cancer Research, London | Truqap | United States | Breast Neoplasms | Astrazeneca Pharmaceuticals Lp | 2023-11-16 | Uterine Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Peritoneal Neoplasms; Metastatic breast cancer; Thyroid Neoplasms; Lung Neoplasms; Prostatic Neoplasms, Castration-Resistant; Lymphoma, Non-Hodgkin; Fallopian Tube Neoplasms; Endometrial Neoplasms; Lymphoma; HR-positive breast cancer; Glioma; Uterine Cervical Neoplasms; Melanoma; Squamous Cell Carcinoma of Head and Neck; Hematologic Neoplasms; Head and Neck Neoplasms; Ovarian Neoplasms; Liver Neoplasms; Rectal Neoplasms; Carcinoma, Renal Cell; Esophageal Neoplasms; Stomach Neoplasms; Solid tumours; Colonic Neoplasms; Triple Negative Breast Neoplasms; Skin Neoplasms; Carcinoma, Ovarian Epithelial; Neoplasms; Pancreatic Neoplasms; Carcinoma, Transitional Cell; Multiple Myeloma | Details |
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Afuresertib | ASB-183; GSK-2110183; GSK-2110183B; GSK-2110183C; GSK-21110183; LAE-002 | Phase 3 Clinical | Glaxosmithkline Plc, Novartis Pharma Ag | Breast Neoplasms; Adenocarcinoma; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Leukemia, Lymphocytic, Chronic, B-Cell; Endometrial Neoplasms; Metastatic breast cancer; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Hematologic Neoplasms; Histiocytosis, Langerhans-Cell; Multiple Myeloma; Triple Negative Breast Neoplasms; Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Solid tumours; Ovarian Neoplasms | Details |
Ipatasertib Dihydrochloride | RG-7440; GCD-0068; GDC-0068; RO-5532961 | Phase 3 Clinical | Array Biopharma, F. Hoffmann-La Roche Ltd | Paranasal Sinus Neoplasms; Hepatic Insufficiency; Urogenital Neoplasms; Neoplasms, Unknown Primary; Endometrial Neoplasms; Carcinoma, Squamous Cell; Lip Neoplasms; Laryngeal Neoplasms; Mouth Neoplasms; Peritoneal Neoplasms; Lymphoma, Non-Hodgkin; Fallopian Tube Neoplasms; Paranasal Sinus Diseases; Uterine Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Endometrioid; Adenocarcinoma; Glioblastoma; Solid tumours; Neoplasm, Residual; Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Cystadenocarcinoma, Serous; Triple Negative Breast Neoplasms; Neoplasms; Ovarian Neoplasms; Hypopharyngeal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Prostatic Neoplasms; Cholangiocarcinoma; Genital Neoplasms, Female; Oropharyngeal Neoplasms | Details |
TIC-10 | ONC201 - Oncoceutics; ONC201/TIC10; NSC-350625; TIC-10; ONC-201 | Phase 3 Clinical | Oncoceutics Inc | Diffuse Intrinsic Pontine Glioma; Central Nervous System Lymphoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Meningioma; Lymphoma, Non-Hodgkin; Leukemia, Myeloid, Acute; Adenomatous Polyps; Endometrial Neoplasms; Glioma; Gliosarcoma; Colorectal Neoplasms; Adenomatous Polyposis Coli; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Mantle-Cell; Breast Neoplasms; Multiple Myeloma; Neoplasms; Myelodysplastic Syndromes; Triple Negative Breast Neoplasms; Thalamic Diseases; Glioblastoma; Diffuse midline glioma; Solid tumours | Details |
Triciribine Phosphate | NSC-154020; PTX-002; API-2; TCN-P; VQD-002-ORAL; VQD-002; NSC-280594; PTX-200 | Phase 2 Clinical | National Cancer Institute | Ovarian Neoplasms; Hematologic Neoplasms; Leukemia; Neoplasms; Breast Neoplasms | Details |
Miransertib | MK-7075; ARQ-092 | Phase 2 Clinical | Arqule Inc | Proteus Infections; Solid tumours; Ovarian Neoplasms; Neoplasms; PIK3CA-Related Overgrowth Spectrum; Proteus Syndrome; Lymphoma; Endometrial Neoplasms | Details |
Iopofosine I-131 | CLR-131; NM404; (131)I-CLR1404; 131I-NM-404; HOT; CLR1404 I-131; I-131-CLR1404; (131)I-NM 404 | Phase 2 Clinical | University Of Michigan | Neuroblastoma; Central Nervous System Lymphoma; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Glioma; Waldenstrom Macroglobulinemia; Diffuse Intrinsic Pontine Glioma; Sarcoma, Ewing; Brain Neoplasms; Lymphoma, B-Cell, Marginal Zone; Osteosarcoma; Lymphoma, Mantle-Cell; Multiple Myeloma; Neoplasms; Lymphoma, Large B-Cell, Diffuse; Rhabdomyosarcoma; Solid tumours; Head and Neck Neoplasms | Details |
Uprosertib/Trametinib Dimethyl Sulfoxide | Phase 2 Clinical | Novartis Pharma Ag | Leukemia, Myeloid, Acute; Endometrial Neoplasms; Uterine Cervical Neoplasms | Details | |
TAS-117 | TAS-117 | Phase 2 Clinical | Otsuka Pharmaceutical Co Ltd, Taiho Pharmaceutical Co Ltd | Solid tumours | Details |
Selumetinib sulfate/MK-2206 | Phase 2 Clinical | Astrazeneca Plc, Merck & Co Inc | Rectal Neoplasms; Triple Negative Breast Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma | Details | |
Uprosertib | GSK-795; GSK-2141795; GSK-2141795C; UPB-795 | Phase 2 Clinical | Glaxosmithkline Plc, Novartis Pharma Ag, National Cancer Institute | Solid tumours; Hematologic Neoplasms; Triple Negative Breast Neoplasms; Neoplasms; Multiple Myeloma; Breast Neoplasms; Leukemia, Myeloid, Acute; Lymphoma; Uterine Neoplasms; Endometrial Neoplasms; Uterine Cervical Neoplasms; Melanoma; Adenocarcinoma | Details |
RX-0301 | RX-0301; WGI-0301; RX-0201 nanoliposomal; RX-0201 Nano; RX-0201-N; RX-0201改良型; HC0301 | Phase 2 Clinical | Rexahn Pharmaceuticals Inc | Liver Neoplasms; Solid tumours; Carcinoma, Hepatocellular | Details |
MK-2206 | NSC-749607; BIND-2206; MK2206; MK-2206 | Phase 2 Clinical | Merck Sharp & Dohme Corp | Leukemia, Myelomonocytic, Juvenile; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Neoplasms, Gonadal Tissue; Gallbladder Neoplasms; Burkitt Lymphoma; Endometrial Neoplasms; Lymphoma, T-Cell; Waldenstrom Macroglobulinemia; Lymphoma; Leukemia, Monocytic, Acute; Glioma; Peritoneal Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Colorectal Neoplasms; Sezary Syndrome; Leukemia, Myeloid, Chronic-Phase; Bile Duct Neoplasms; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Lymphoproliferative Disorders; Cholangiocarcinoma; Carcinoma, Adenosquamous; Adenocarcinoma; Breast Neoplasms, Male; Mycosis Fungoides; Melanoma; Leukemia, Prolymphocytic; Leukemia, T-Cell; Carcinoma, Non-Small-Cell Lung; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Central Nervous System Lymphoma; Carcinoma, Hepatocellular; Breast Neoplasms; Lymphoma, T-Cell, Cutaneous; Lymphoma, Large-Cell, Anaplastic; Adenocarcinoma, Mucinous; Thymoma; Lung Neoplasms; Leukemia, Myeloid, Acute; Fallopian Tube Neop | Details |
NTQ-1062 | NTQ-1062; NTQ1062 | Phase 2 Clinical | Nanjing Zhengda Tianqing Pharmaceutical Co Ltd | Solid tumours; Breast Neoplasms; HR-positive breast cancer | Details |
HZB-0071 | HZB-0071 | Phase 1 Clinical | Wuxi Apptec Co Ltd, Heilongjiang Zbd Pharmaceutical Co Ltd | Neoplasms | Details |
Rupitasertib | DIACC3010; M-2698; MSC-2363318A; DIACC-3010 | Phase 1 Clinical | Emd Serono Inc | Solid tumours; Stomach Neoplasms; Glioblastoma; Breast Neoplasms | Details |
Honokiol | HU-002; JRF-101 | Phase 1 Clinical | Anacor Pharmaceuticals Inc | Metabolic Dysfunction-Associated Steatotic Liver Disease; Gingival Diseases; Carcinoma, Non-Small-Cell Lung | Details |
CMX-2043 | LIP-EA; CMX-2043; R-LIP-EA-OH | Phase 1 Clinical | Ischemix Llc | Brain Injuries, Traumatic; Angina, Unstable; Coronary Artery Disease | Details |
Hu-7691 | Hu-7691 | Phase 1 Clinical | Zhejiang University | Solid tumours; Neoplasms | Details |
Oxysterols (Intsel Chimos) | Clinical | Centre National De La Recherche Scientifique (Cnrs) | Glioma | Details |
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