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GDNF

Brief Information

Name:Glial cell line-derived neurotrophic factors
Target Synonym:Glial Cell Line-Derived Neurotrophic Factors
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:4
Lastest Research Phase:NDA/BLA

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Kat. Nr. Arten Produktbeschreibung Struktur Reinheit Merkmal
GDF-M5245 Mouse Mouse GDNF / ATF Protein, His Tag (MALS verified)
GDF-M5245-structure
GDF-M5245-sds
GDF-H5219 Human Human GDNF / ATF / hGDNF Protein, premium grade
GDF-H5219-structure
GDF-H5219-sds
ACRO Quality

Part of Bioactivity data

GDF-M5245-MALS-HPLC
GDNF MALS images

The purity of Mouse GDNF, His Tag (Cat. No. GDF-M5245) is more than 90% and the molecular weight of this protein is around 40-50 kDa verified by SEC-MALS.

GDF-H5219-ELISA
 GDNF ELISA

Immobilized Human GDNF Protein, premium grade (Cat. No. GDF-H5219) at 2 μg/mL (100 μL/well) can bind Human GFR alpha-1, His Tag (Cat. No. GF1-H5224) with a linear range of 0.2-4 ng/mL (QC tested).

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
AAV2-GDNF AB-1005; AMT-140 Phase 2 Clinical Lund University Foundation, National Institute Of Neurological Disorders And Stroke, Uniqure Biopharma Bv, Uc San Francisco Parkinson Disease; Multiple System Atrophy Details
NRO-1 NRO-1; SI-01 Phase 2 Clinical Senju Pharmaceutical Co Ltd Xerophthalmia Details
AMT-130 AAV5-miSNP15; AAV5-miSNP7; AMT-130; AAV5-miHtt12 Phase 2 Clinical Amsterdam Molecular Therapeutics, Uniqure Huntington Disease Details
AAV2-GDNF AB-1005; AMT-140 Phase 2 Clinical Lund University Foundation, National Institute Of Neurological Disorders And Stroke, Uniqure Biopharma Bv, Uc San Francisco Parkinson Disease; Multiple System Atrophy Details
NRO-1 NRO-1; SI-01 Phase 2 Clinical Senju Pharmaceutical Co Ltd Xerophthalmia Details
AMT-130 AAV5-miSNP15; AAV5-miSNP7; AMT-130; AAV5-miHtt12 Phase 2 Clinical Amsterdam Molecular Therapeutics, Uniqure Huntington Disease Details

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