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CLEC-2

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Kat. Nr. Arten Produktbeschreibung Struktur Reinheit Merkmal
CL2-H5254 Human Human CLEC-2 / CLEC1B Protein, Fc Tag (MALS & SPR verified)
CL2-H5254-structure
CL2-H5254-sds
CL2-H5247 Human Human CLEC-2 / CLEC1B Protein, His Tag (MALS verified)
CL2-H5247-structure
CL2-H5247-sds
ACRO Quality

Part of Bioactivity data

CL2-H5254-SPR
 CLEC-2 SPR

Human Podoplanin, His Tag (Cat. No. PON-H52H3) immobilized on CM5 Chip can bind Human CLEC-2, Fc Tag (Cat. No. CL2-H5254) with an affinity constant of 0.495 μM as determined in a SPR assay (Biacore 8K) (QC tested).

CL2-H5247-ELISA
 CLEC-2 ELISA

Immobilized Human CLEC-2, His Tag (Cat. No. CL2-H5247) at 5 μg/mL (100 μL/well) can bind Human Podoplanin, Fc Tag (Cat. No. PON-H5254) with a linear range of 0.3-20 ng/mL (QC tested).

Synonym Name

CLEC-2/CLEC1B/C-type Lectin-like Receptor 2

Background

C-type lectin-like receptor 2 (CLEC-2) is a hemITAM containing receptor that is highly expressed on platelets and regulates many of the non-classical functions of these cells, including in inflammation and infection.

Clinical and Translational Updates

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