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FOLR4

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FO4-H52H3 Human Human FOLR4 Protein, His Tag (MALS verified)
FO4-H52H3-structure
FO4-H52H3-sds
ACRO Quality

Part of Bioactivity data

FO4-H52H3-MALS-HPLC
FOLR4 MALS images

The purity of Human FOLR4, His Tag (Cat. No. FO4-H52H3) is more than 85% and the molecular weight of this protein is around 24-36kDa verified by SEC-MALS.

Synonym Name

folate receptor 4 (delta) homolog (mouse),Folbp3,FOLR4,FR-delta,LOC390243,probable folate receptor delta

Background

FOLR4, also know as Sperm-egg fusion protein Juno(IZUMO1R) is  receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.

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