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| Kat. Nr. | Arten | Produktbeschreibung | Struktur | Reinheit | Merkmal |
|---|---|---|---|---|---|
| CHEK-ATP186 | Human | HEK293/Human PTK7 Stable Cell Line | |||
| PT7-M5256 | Mouse | Mouse PTK7 / CCK4 Protein, Fc Tag (MALS verified) |  |
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| PT7-H82F5 | Human | Biotinylated Human PTK7 / CCK4 protein, Fc,Avitag™ (MALS verified) |  |
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| PT7-R52H6 | Rat | Rat PTK7 / CCK4 Protein, His Tag (MALS verified) |  |
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| PT7-R5255 | Rat | Rat PTK7 / CCK4 Protein, Fc Tag |  |
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| PT7-C52H3 | Cynomolgus / Rhesus macaque | Cynomolgus / Rhesus macaque PTK7 / CCK4 Protein, His Tag (MALS verified) |  |
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| PT7-R52H4 | Rabbit | Rabbit PTK7 / CCK4 Protein, His Tag (MALS verified) |  |
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| PT7-M52H3 | Mouse | Mouse PTK7 / CCK4 Protein, His Tag (MALS verified) |  |
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| PT7-H5253 | Human | Human PTK7 / CCK4 Protein, Fc Tag (MALS verified) |  |
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| PT7-H82E5 | Human | Biotinylated Human PTK7 / CCK4 protein, His,Avitag™ (MALS verified) |  |
|
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| PT7-H52H3 | Human | Human PTK7 / CCK4 Protein, His Tag (MALS verified) |  |
|
Expression analysis of human PTK7 on HEK293/Human PTK7 Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human PTK7 Stable Cell Line or negative control cell using anti-human PTK7 antibody followed by fixation with 4% paraformaldehyde, and then stained with PE anti-human IgG Fc antibody.
Immobilized Cynomolgus / Rhesus macaque PTK7, His Tag (Cat. No. PT7-C52H3) at 1 μg/mL (100 μL/well) can bind Cofetuzumab Pelidotin with a linear range of 0.06-2 ng/mL (Routinely tested).
The purity of Mouse PTK7 Protein, Fc Tag (Cat. No. PT7-M5256) is more than 90% and the molecular weight of this protein is around 240-270 kDa verified by SEC-MALS.
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| PRO-1107 | PRO-1107 | Phase 2 Clinical | ProfoundBio (Suzhou) Co Ltd | Solid tumours; Ovarian Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Endometrial Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| Cofetuzumab Pelidotin | PF-06647020; PF-6647020; PTK7-ADC; PF-06523435; PF-7020; hu-24; ABBV-647; Anti-PTK7 ADC; h6M24-vc0101 | Phase 1 Clinical | Abbvie Inc, Stemcentrx Inc | Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| PRO-1107 | PRO-1107 | Phase 2 Clinical | ProfoundBio (Suzhou) Co Ltd | Solid tumours; Ovarian Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Endometrial Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| Cofetuzumab Pelidotin | PF-06647020; PF-6647020; PTK7-ADC; PF-06523435; PF-7020; hu-24; ABBV-647; Anti-PTK7 ADC; h6M24-vc0101 | Phase 1 Clinical | Abbvie Inc, Stemcentrx Inc | Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
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