Acrobiosystems for English
icon_bulk_orderAnfrage Sammelbestellung/Schnellbestellung
user
  1. Übersicht
  2. Mein Profil
  3. Meine Adresse
  4. Meine Bestellungen
  5. Acro-Mitgliedschaft
Login Registrieren
Promotion
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2
0
Es befinden sich keine Waren im Warenkorb !
Mein Warenkorb|Check Out
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Start > CD58

CD58

Brief Information

Name:Lymphocyte function-associated antigen 3
Target Synonym:CD58 Antigens,Surface glycoprotein LFA-3,LFA3,LFA-3,CD58 Molecule,CD58 Antigen,CD58,CD58 Antigen, (Lymphocyte Function-Associated Antigen 3)
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Clinical

Product ListCompare or Buy

Product> Filter Results
Nach Produktstatus:
Nach Produktkategorie :
Nach Arten:
Nach Markierungen:
Nach Konjugaten:
Kat. Nr. Arten Produktbeschreibung Struktur Reinheit Merkmal
LF3-H5256 Human Human CD58 / LFA-3 Protein, Fc Tag
LF3-H5256-structure
LF3-H5256-sds
LF3-H5225 Human Human CD58 / LFA-3 Protein, His Tag
LF3-H5225-structure
LF3-H5225-sds
ACRO Quality

Part of Bioactivity data

LF3-H5256-BLI
CD58 BLI

Loaded bind Human CD58, Fc Tag (Cat. No. LF3-H5256) on Protein A Biosensor, can bind Human CD2, His Tag (Cat. No. CD2-H5226) with an affinity constant of 8.42 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol
LF3-H5225-BLI
CD58 BLI

Loaded Human CD2, Fc Tag (Cat. No. CD2-H5258) on Protein A Biosensor, can bind Human CD58, His Tag (Cat. No. LF3-H5225) with an affinity constant of 2.3 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol

Synonym Name

CD58,LFA3,Ag3

Background

CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Recombinant human LFA-3-antibody fusion protein (Taizhou Mabtech Pharmaceutical) Clinical Taizhou Maibo Taike Biotechnology Co Ltd Psoriasis Details
Recombinant human LFA-3-antibody fusion protein (Taizhou Mabtech Pharmaceutical) Clinical Taizhou Maibo Taike Biotechnology Co Ltd Psoriasis Details

This web search service is supported by Google Inc.

totop
Call us
Call us

Germany+49 800 0826645

United Kingdom+44 808 281 3436

Netherlands+31 800 0224992

Switzerland+41 800 040 012

France+33 800 90 78 85

Sweden+46 20 12 76 94

Denmark+45 80 83 07 62

Belgium+32 800 27 125

Email
E-Mail
order@acrobiosystems.com
Fax
Fax
+1 888-377-6111
Address
Address
Lichtstrasse 35,4056 Basel, Switzerland
linkedin twitter facebook youtube

Nachricht schicken

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap