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3CL-Mpro

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Synonym Name

3CL-Mpro,3C-like main protease

Background

The Main protease (M pro) is a key enzyme for 2019-nCoV replication. It is also encoded by the polypeptide and responsible for processing the polypeptide into functional proteins. The M pro has similar cleavage-site specificity to that of picornavirus 3C protease (3C pro), thus is also known as 3C 3C-like main protease (3CL Mpro).

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