Explore insights across the ADC development workflow, from target discovery and conjugation to bioanalysis, CMC, and advances in next-generation ADC research.

HotJul 31, 2026
Antibody internalization is a fundamental step in the development of antibody therapeutics and antibody–drug conjugates (ADCs), providing valuable insights into intracellular antibody behavior following target binding. A range of experimental approaches has been developed to evaluate antibody internalization, each offering unique advantages and suited to different research applications.
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HotJul 31, 2026
Development and Optimization of a pH-Sensitive Fluorescence-Based Assay for Quantitative Antibody Internalization Analysis
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HotJul 22, 2026
Antibody-drug conjugates (ADCs) undergo in vivo processes such as deconjugation, linker cleavage, and payload release, generating multiple circulating molecular species during systemic exposure. Consequently, ADC pharmacokinetic (PK) studies often incorporate multiple bioanalytical measurements to characterize different molecular forms of the drug.
Read moreReceive expert perspectives, research trends, and workflow guidance across emerging therapeutic fields.
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