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Apolipoprotein E

Apolipoprotein E Overview

English NameApolipoprotein EApproved Drugs0
Drugs in Clinical Trials2Target SynonymAPOE，Apolipoprotein E，Alzheimer Disease 2 (APOE*E4-Associated， Late Onset)，Apolipoprotein E3，LDLCQ5，Apo-E，LPG，AD2，Apolipoproteins E
Highest Development StagePhase 2 Clinical
English NameApolipoprotein E
Target SynonymAPOE，Apolipoprotein E，Alzheimer Disease 2 (APOE*E4-Associated， Late Onset)，Apolipoprotein E3，LDLCQ5，Apo-E，LPG，AD2，Apolipoproteins E
Approved Drugs0
Drugs in Clinical Trials2
Highest Development StagePhase 2 Clinical

Apolipoprotein E Product List

  • Product Category

    Protein (11)

  • Product Status

    Launched (11)

  • Species

    Human (9)Mouse (1)Cynomolgus (1)

  • Tag

    His Tag (5)His Tag & Avi Tag (4)Tag Free (2)

  • Conjugate

    Unconjugated (7)Biotin-labeled (4)

Total: 11
  • 1
  • 2

Apolipoprotein E Background

APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.

Apolipoprotein E Synonyms

Apolipoprotein E,APOE,Apo-E
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  • Product List