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Tau

Tau Overview

English NameMicrotubule-associated protein tauApproved Drugs1
Drugs in Clinical Trials36Target SynonymMAPT，MTBT1，Paired helical filament-tau，MAPTL，Microtubule Associated Protein Tau，G Protein Beta1/Gamma2 Subunit-Interacting Factor 1，Protein Phosphatase 1， Regulatory Subunit 103，Neurofibrillary Tangle Protein，PHF-Tau，TAU，Microtubule-Associated Protein Tau， Isoform 4，Microtubule-Associated Protein Tau，PPP1R103，FTDP-17，MTBT2，DDPAC，MSTD，PPND，tau Proteins，MGC138549，FLJ31424
Highest Development StagePhase 3 Clinical
English NameMicrotubule-associated protein tau
Target SynonymMAPT，MTBT1，Paired helical filament-tau，MAPTL，Microtubule Associated Protein Tau，G Protein Beta1/Gamma2 Subunit-Interacting Factor 1，Protein Phosphatase 1， Regulatory Subunit 103，Neurofibrillary Tangle Protein，PHF-Tau，TAU，Microtubule-Associated Protein Tau， Isoform 4，Microtubule-Associated Protein Tau，PPP1R103，FTDP-17，MTBT2，DDPAC，MSTD，PPND，tau Proteins，MGC138549，FLJ31424
Approved Drugs1
Drugs in Clinical Trials36
Highest Development StagePhase 3 Clinical

Tau Product List

  • Product Category

    Protein (16)Cell (1)Antibody (2)

  • Product Status

    Launched (19)

  • Species

    Human (16)Cynomolgus (1)Mouse (2)

  • Tag

    His Tag (7)Tag Free (9)GFP Tag (1)- (1)Mouse IgG1 (1)

  • Conjugate

    Unconjugated (18)- (1)

Total: 19
  • 1
  • 2

Tau Background

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies. Tau-441 is known as "2N4R," "Isoform Tau-F," "Tau-4" or "Tau 441", which consisting of 441 amino acid. Tau-441 is a potential therapeutic target for pathogenesis.

Tau Synonyms

DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU

Product Reviews

  • P***g2021-08-24
    5People Like
    Human Tau-441 / 2N4R Protein, His Tag
    I have purchased multiple antigens from ACRO for discovery projects and I have found that the quality of antigens purchased from Acro is great!! Acro has become by go to vendor when I am looking for quality antigens. In addition, Acro also provides an impressive range of formats for each antigens, including different tags. Not to mention, their customer service team is fantastic. Overall, a great company to work with.
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