CD19

CD19

CD19 Overview

Molecule Name
B-lymphocyte antigen CD19
Synonyms
CD19,B4,CVID3,MGC12802
Drug Development Progress
Drugs in Clinical Trials440
Approved Drugs14
Highest Development StageApproved
Target Synonym
Differentiation antigen CD19,CD19 Molecule,B-Lymphocyte Surface Antigen B4,CD19 Antigen,B-Lymphocyte Antigen CD19,CVID3,B4,Antigens, CD19,CD19,T-cell surface antigen Leu-12
Background
FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.

CD19 Product List

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  • C***z2026-06-05
    We used CD19 for our binding assays. The Antigen was of good quality, well-behaved, and arrived quickly for our urgent need. I appreciate Acro's suite of QC data provided with each antigen.
  • P***y2023-06-20
    We use this reagent to detect CD19 CAR on the cell surface by flow cytometry. We use it at the recommended dose and are very happy with the results.
  • S*** 2023-02-01
    I run lentiviral titers at work and desperately needed a CD19 antibody due backorder. I stumbled upon Acro Bio's PE-CD19 abs and it worked wonders! When I first used it, there was higher CD19 expression than I typically see in my vectors. I performed a comparison study testing out various CD19 (some conjugated some not conjugated) antibodies. The Acro Bio antibody had the best performance! It showed greater binding than the usual CD19 antibody I use. After I conducted this study, my company set their heart's desire to Acro's CD19 antibody. We solely use this antibody for all our CD19 projects. AND its more affordable than many other CD19 antibodies on the market! This is such a phenomenal antibody! I highly recommend it!