DLL4

DLL4 Molekülinformation

Englischer Name	Delta-like protein 4	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	3	Target-Alias	Delta-Like Protein 4，Notch Ligand Delta-2，DLL4，Delta4，Delta-Like 4 (Drosophila)，Delta-Like 4 Homolog (Drosophila)，AOS6，Hdelta2，Notch Ligand DLL4，Delta Like Canonical Notch Ligand 4，Delta 4，Delta Ligand 4，Delta-Like 4 Protein，Drosophila Delta Homolog 4，Delta-Like 4 Homolog
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Delta-like protein 4
Target-Alias	Delta-Like Protein 4，Notch Ligand Delta-2，DLL4，Delta4，Delta-Like 4 (Drosophila)，Delta-Like 4 Homolog (Drosophila)，AOS6，Hdelta2，Notch Ligand DLL4，Delta Like Canonical Notch Ligand 4，Delta 4，Delta Ligand 4，Delta-Like 4 Protein，Drosophila Delta Homolog 4，Delta-Like 4 Homolog
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	3
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

DLL4 Produktliste

Attribut
Protein (10)Cell Grade Beads (4)Kits (2)
Produktbibliothek
Online (16)
Spezies
Human (13)- (3)
Etikett
Fc Tag (6)His Tag (1)His Tag & Avi Tag (2)- (6)Fc Tag & Avi Tag (1)
Marker
Unconjugated (7)Biotin-labeled (3)- (6)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT DL4-H5255	Human	HEK293	Human DLL4 Protein, Fc Tag, premium grade (Flagship)	In den Warenkorb legen
HOT DL4-H5259	Human	HEK293	Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)	In den Warenkorb legen
HOT DL4-H82E6	Human	HEK293	Biotinylated Human DLL4 Protein, His,Avitag™, premium grade	In den Warenkorb legen
HOT GMP-DL4H23	Human	HEK293	GMP Biotinylated Human DLL4 Protein, His,Avitag™	In den Warenkorb legen
HOT GMP-DL4H27	Human	HEK293	GMP Human DLL4 Protein, Fc Tag (Flagship)	In den Warenkorb legen
HOT GMP-DL4H27GB01	Human	HEK293	CytoPak GMP Human DLL4 Protein, Fc Tag (Flagship)	In den Warenkorb legen
HOT GMP-DL4H28	Human	HEK293	GMP Human DLL4 Protein, Fc Tag	In den Warenkorb legen
HOT MBS-C013	Human	-	ActiveMax® Human DLL4 μBeads, premium grade (for cells)	In den Warenkorb legen
DL4-H5227	Human	HEK293	Human DLL4 Protein, His Tag, low Endotoxin (MALS verified)	In den Warenkorb legen
DL4-H5256	Human	HEK293	Human DLL4 Protein, Fc Tag, Research Grade (Flagship)	In den Warenkorb legen

Gesamtmenge16

Produktanfrage

DLL4 Molekülhintergrund

Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.

DLL4 Molekülalias

DLL4,Delta4

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Tovecimig	ES-104; NOV-1501; CTX-009; HD-B001A; HDB001A; TR-009; ABL001; ABL-001	Phase 3 Clinical	Abl Bio Inc	Ampullary Carcinoma; Bile Duct Neoplasms; Biliary Tract Neoplasms; Cholangiocarcinoma; Colonic Neoplasms; Colorectal Neoplasms; Gallbladder Neoplasms; Glioblastoma; Rectal Neoplasms; Solid tumours	Details
Navicixizumab	OMP-305B83	Phase 3 Clinical	Oncomed Pharmaceuticals Inc	Colorectal Neoplasms; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Solid tumours; Stomach Neoplasms; Triple Negative Breast Neoplasms	Details
Dilpacimab	ABT-165; DVD-Ig ABT-165	Phase 1 Clinical	Abbvie Inc	Neoplasms; Solid tumours	Details

Produktrezensionen

A***r2025-11-15
0Menschen mögen
Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)
I have been using ACRO Biosystems products since 2021, especially DLL4 Fc proteins (DL4-H5259), refer to our published article: https://pubmed.ncbi.nlm.nih.gov/37795096/, where we have used Acro-products and obtained excellent results. I am very satisfied with the consistent quality and reliability of ACRO’s products. Thanks, Ankit Tanwar Staff Scientist AECOM, NY
Z***a2022-07-06
1Menschen mögen
Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)
This product was extremely useful for our T cell work. The vial it came in was easy to use (sometimes you'd be surprised how obtuse the packaging of a compound can be by certain companies) and has not lead to any issues with our research in many months. The only obstacle we have ever faced with adherent cells was as a result of our flat bottom plates being too old (and thus the coating wore off). So this product was more stable and consistent than the plates we put them on!