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DLL4

DLL4

DLL4 Molekülinformation

Molecule Name
Delta-like protein 4
Molekülalias
DLL4,Delta4
Drug Development Progress
Anzahl der klinischen Arzneimittel3
Anzahl der inverkehr gebrachten Arzneimittel0
Höchste Forschungs- und EntwicklungsphasePhase 3 Clinical
Target-Alias
Delta-Like Protein 4，Notch Ligand Delta-2，DLL4，Delta4，Delta-Like 4 (Drosophila)，Delta-Like 4 Homolog (Drosophila)，AOS6，Hdelta2，Notch Ligand DLL4，Delta Like Canonical Notch Ligand 4，Delta 4，Delta Ligand 4，Delta-Like 4 Protein，Drosophila Delta Homolog 4，Delta-Like 4 Homolog
Molekülhintergrund
Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.

DLL4 Produktliste

Species
  • Human（10）
Tag
  • Fc Tag（6）
  • His Tag & Avi Tag（2）
  • Fc Tag & Avi Tag（1）
  • His Tag（1）
Host
  • HEK293（10）
Conjugate
  • Unconjugated（7）
  • Biotin-labeled（3）
Grade
  • GMP（4）
  • PG (pre-GMP)（3）
  • RUO（3）
Low Endotoxin
  • Yes（2）
  • No（8）
MoleculeCat. No.Product NameArtHostStructurePurityActivitySize&PriceAdd to Cart
DLL4
HOTDMF
GMP-DL4H27GB01
CytoPak GMP Human DLL4 Protein, Fc Tag (Flagship)
Human
HEK293
SDS-PAGE
SPRCELL BASE
Anfrage
1mg
DLL4
HOTAvitag
DL4-H82E6
Biotinylated Human DLL4 Protein, His,Avitag™, premium grade
Human
HEK293
MALSSDS-PAGE
ELISASPRCELL BASE

$225.00

25ug
DLL4
HOTDMF
GMP-DL4H28
GMP Human DLL4 Protein, Fc Tag
Human
HEK293
SDS-PAGE
SPRCELL BASE

$1020.00

200ug
DLL4
HOT
DL4-H5259
Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)
Human
HEK293
MALSSDS-PAGE
ELISASPRCELL BASE

$340.00

100ug
DLL4
HOT
DL4-H5255
Human DLL4 Protein, Fc Tag, premium grade (Flagship)
Human
HEK293
MALSSDS-PAGE
SPRCELL BASE

$310.00

100ug
DLL4
HOTAvitagDMF
GMP-DL4H23
GMP Biotinylated Human DLL4 Protein, His,Avitag™
Human
HEK293
SDS-PAGE
SPR

$1110.00

200ug
DLL4
HOTDMF
GMP-DL4H27
GMP Human DLL4 Protein, Fc Tag (Flagship)
Human
HEK293
SDS-PAGE
SPRCELL BASE

$1020.00

200ug
DLL4
DL4-H5227
Human DLL4 Protein, His Tag, low Endotoxin (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISA

$260.00

100ug
DLL4
DL4-H5256
Human DLL4 Protein, Fc Tag, Research Grade (Flagship)
Human
HEK293
MALSSDS-PAGE
SPRCELL BASE

$150.00

20ug
DLL4
Avitag
DL4-H82F7
Biotinylated Human DLL4 Protein, Fc,Avitag™, premium grade
Human
HEK293
MALSSDS-PAGE
ELISACELL BASE

$188.00

25ug
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Resources

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
TovecimigES-104; NOV-1501; CTX-009; HD-B001A; HDB001A; TR-009; ABL001; ABL-001Phase 3 ClinicalAbl Bio Inc
Ampullary Carcinoma; Bile Duct Neoplasms; Biliary Tract Neoplasms; Cholangiocarcinoma; Colonic Neoplasms; Colorectal Neoplasms; Gallbladder Neoplasms; Glioblastoma; Rectal Neoplasms; Solid tumours
Details
NavicixizumabOMP-305B83Phase 3 ClinicalOncomed Pharmaceuticals Inc
Colorectal Neoplasms; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Solid tumours; Stomach Neoplasms; Triple Negative Breast Neoplasms
Details
DilpacimabABT-165; DVD-Ig ABT-165Phase 1 ClinicalAbbvie Inc
Neoplasms; Solid tumours
Details
Customer Reviews
  • A***r2025-11-15
    Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)
    I have been using ACRO Biosystems products since 2021, especially DLL4 Fc proteins (DL4-H5259), refer to our published article: https://pubmed.ncbi.nlm.nih.gov/37795096/, where we have used Acro-products and obtained excellent results. I am very satisfied with the consistent quality and reliability of ACRO’s products. Thanks, Ankit Tanwar Staff Scientist AECOM, NY
  • Z***a2022-07-06
    Human DLL4 Protein, Fc Tag, low endotoxin (MALS & SPR verified)
    This product was extremely useful for our T cell work. The vial it came in was easy to use (sometimes you'd be surprised how obtuse the packaging of a compound can be by certain companies) and has not lead to any issues with our research in many months. The only obstacle we have ever faced with adherent cells was as a result of our flat bottom plates being too old (and thus the coating wore off). So this product was more stable and consistent than the plates we put them on!