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IFN-gamma

IFN-gamma Overview

English Name	Interferon gamma	Approved Drugs	4
Drugs in Clinical Trials	13	Target Synonym	Immune interferon，Interferon gamma，IFNG，IFN-Gamma，IFG，IFI，Interferon-gamma
Highest Development Stage	Approved

English Name	Interferon gamma
Target Synonym	Immune interferon，Interferon gamma，IFNG，IFN-Gamma，IFG，IFI，Interferon-gamma
Approved Drugs	4
Drugs in Clinical Trials	13
Highest Development Stage	Approved

IFN-gamma Product List

Product Category
Protein (5)Antibody (6)Kits (9)
Product Status
Launched (19)In Research (1)
Species
Human (9)Mouse (11)
Tag
Tag Free (3)- (15)His Tag (1)His Tag & Avi Tag (1)
Conjugate
Unconjugated (9)- (9)Biotin-labeled (2)

Cat. No.	Species	Host	Product Description
HOT CEA-C245	Human	-	Human IFN-gamma Quick ELISA Kit
HOT CRS-A017	Human	-	Human Interferon-γ (IFN-γ) ELISA Kit
HOT GMP-IFGH24	Human	HEK293	GMP Human IFN-gamma Protein
HOT IFG-H4211	Human	HEK293	Human IFN-gamma / IFNG Protein, premium grade
HOT RAS-SP002	Mouse	-	Mouse Interferon-γ (IFN-γ) ELISPOT Kit
CEA-C006	Human	-	Human IFN-γ ELISA Kit, PRO
CRS-D001	Human	-	Human Interferon-γ (IFN-γ) ELISA Assay Pair
IFG-H5213	Human	HEK293	Human IFN-gamma / IFNG Protein, Research Grade
RAS-SP001	Human	-	Human Interferon-γ (IFN-γ) ELISPOT Kit
RES-A028	Human	-	resDetect™ Human Interferon-γ(IFN-γ) ELISA Kit (Residue Testing)

Total: 20

IFN-gamma Background

Interferon-gamma (IFN-γ/IFNG) is a dimerized soluble cytokine that is the only member of the type II class of interferon. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-γ belongs. IFN-gamma has been used in a wide variety of clinical indications. Interferon-gamma (IFNgamma) is a central regulator of the immune response and signals via the Janus Activated Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT) pathway. Interferon gamma has broader roles in activation of innate and adaptive immune responses to viruses and tumors, in part through upregulating transcription of genes involved in cell cycle regulation, apoptosis, and antigen processing/presentation. Despite this, rodent and human trophoblast cells show dampened responses to IFNG that reflect the resistance of these cells to IFNG-mediated activation of major histocompatibility complex (MHC) class II transplantation antigen expression.

IFN-gamma Synonyms

Interferon-gamma ,Interferon-γ

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
PDS-0101	PDS-0101B; PDS-0101C; PDS-0101; PDS-0101A; PDS-101	Phase 3 Clinical	Pds Biotechnology Corp	Anus Neoplasms; Carcinoma, Squamous Cell; Head and Neck Neoplasms; HIV Infections; Oropharyngeal Neoplasms; Papillomavirus Infections; Uterine Cervical Neoplasms; Vulvar Neoplasms	Details
Tadekinig alfa	r-hIL-18BP; IL-18BP	Phase 3 Clinical	Ab2 Bio Ltd	Autoimmune Lymphoproliferative Syndrome; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation Syndrome	Details
SFA-002	SFA-002; SFA002	Phase 3 Clinical	SFA Therapeutics Inc	Arthritis, Rheumatoid; Plaque psoriasis; Psoriasis	Details
IMNN-001	GEN-1; EGEN-001; IMNN-001; phIL-12-005/PPC	Phase 3 Clinical	Expression Genetics	Carcinoma, Endometrioid; Carcinoma, Ovarian Epithelial; Colorectal Neoplasms; Cystadenocarcinoma; Cystadenocarcinoma, Serous; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms	Details
TAX-2	TAX-2; AP-01; AP-02	Phase 2 Clinical	Centre National De La Recherche Scientifique (Cnrs), University of Reims	Solid tumours; Thrombosis	Details
OCH-NCNP1	OCH-NCNP1	Phase 2 Clinical	Keio University	Crohn Disease; Multiple Sclerosis	Details
KIO-101	PP-001; KIO-101; KIO-104	Phase 2 Clinical	4sc Ag	Conjunctival Diseases; Dry Eye Syndromes; Eye Diseases; Keratoconjunctivitis; Uveitis; Xerophthalmia	Details
ASN-002 (Ascend Biopharmaceuticals)	TG-1042; Ad-IFNγ; SP-002 (Ascend Biopharmaceuticals)	Phase 2 Clinical	Transgene Sa	Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Lymphoma, B-Cell; Skin Melanoma; Skin Neoplasms; Solid tumours	Details
Indemakitug	EI-001	Phase 2 Clinical	Elixiron Immunotherapeutics Inc	Vitiligo	Details
IFN-gamma-secreting HAdV antigen specific T cells (Case Comprehensive Cancer Center)		Phase 1 Clinical	Case Comprehensive Cancer Center	Hematopoietic stem cell transplantation (HSCT)	Details
Recombinant human interferon gamma adenovirus injection (Guangzhou Dabo Biological Products)		Phase 1 Clinical	Guangzhou Dabo Biological Products Co Ltd	Liver Neoplasms; Nasopharyngeal Neoplasms; Prostatic Neoplasms, Castration-Resistant	Details
TAGX-0003	TAGX-0003; CGB-600	Phase 1 Clinical	TagCyx Biotechnologies	Alopecia Areata; Autoimmune Diseases; Cystitis, Interstitial; Skin Diseases; Vitiligo	Details
[89Zr]Zr-DFO-emapalumab	[89Zr]Zr-DFO-emapalumab	Phase 1 Clinical	Barbara Ann Karmanos Cancer Institute	Carcinoma, Non-Small-Cell Lung	Details

Marketed Drug Information

English Name	Research Code	Highest Development Stage	Company	Earliest Brand Name	Earliest Approval Country	Earliest Indication	Earliest Approval Company	Earliest Approval Date	Indication	Clinical Trial
Cadi-05	Cadi-05	Approved	National Institute Of Allergy And Infectious Diseases (Niaid)	Immuvac, Leprovac, Mycidac-C	India	Leprosy; Carcinoma, Non-Small-Cell Lung	null	1998-01-01	Carcinoma, Non-Small-Cell Lung; Leprosy; Squamous Cell Carcinoma of Head and Neck	Details
Propagermanium	SK-818; SK-818C	Approved	Sanwa Kagaku Kenkyusho Co Ltd	Serocion	Japan	Hepatitis B	Sanwa Kagaku Kenkyusho Co Ltd	1994-01-01	Hepatitis B	Details
Emapalumab	NI-0501	Approved	Novimmune Sa	Gamifant	United States	Lymphohistiocytosis, Hemophagocytic	Novimmune Sa	2018-11-20	Arthritis, Juvenile; Cytopenia; Dermatomyositis; Hematopoietic stem cell transplantation (HSCT); Immune System Diseases; Lung Diseases, Interstitial; Lupus Erythematosus, Systemic; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation Syndrome; Polyendocrinopathies, Autoimmune; Rare Diseases; Sepsis; Still's Disease, Adult-Onset	Details
Thalidomide	NSC-66847; NSC-527179; K-17; FPF-300; FPF300	Approved	Celgene Corp	Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled	Mainland China	Leprosy, Lepromatous; Multiple Myeloma	Changzhou Pharmaceutical Factory	1982-01-01	Acquired Immunodeficiency Syndrome; Adenocarcinoma, Clear Cell; Adenoma, Islet Cell; Amyotrophic Lateral Sclerosis; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anemia, Sideroblastic; Angiodysplasia; Appendiceal Neoplasms; Arachnoiditis; Arteriovenous Malformations; Axial Spondyloarthritis; beta-Thalassemia; Burning Mouth Syndrome; Carcinoid Tumor; Carcinoma, Adenosquamous; Carcinoma, Hepatocellular; Cholangitis, Sclerosing; Colorectal Neoplasms; Cough; Endometrial Neoplasms; Endometriosis; Epilepsy; Erythema Nodosum; Gastric Antral Vascular Ectasia; Gastrointestinal Hemorrhage; Genetic Diseases, Inborn; Glioma; Graft vs Host Disease; Head and Neck Neoplasms; Hemoglobinopathies; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Hormone-Resistant Prostate Neoplasms; Hypertension, Portal; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Leiomyosarcoma; Leprosy, Lepromatous; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Chronic; Liver Neoplasms; Lung Neoplasms	Details

Product Reviews

M***r2025-10-31
0People Like
Human IFN-gamma Quick ELISA Kit
Reliable and easy-to-use ELISA kit with high sensitivity and consistent results. Standards and controls performed as expected, and the shorter assay time is a great advantage for our studies.