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218 linker

218 linker Product List

  • Product Category

    Antibody (6)

  • Product Status

    Launched (6)

  • Species

    Rabbit (6)

  • Tag

    - (6)

  • Conjugate

    APC Labeled (1)PE Labeled (1)AF488 Labeled (1)Unconjugated (2)AF647 Labeled (1)

Total: 6
  • 1

218 linker Background

The whitlow/218 linker, with the sequence GSTSGSGKPGSGEGSTKG, is a commonly used synthetic peptide linker. Whitlow/218 linker often leveraged to connect the variable heavy (VH) domain and variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that utilize an extracellular domain scFv for target antigen recognition. The scFv containing the 218 linker showed reduced aggregation and was found to be more stable to proteolysis in vitro.
  • Product List