Hepatitis B core antigen/HBcAg (HBV)

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Hepatitis B core antigen/HBcAg (HBV) Background

Hepatitis B virus (HBV) is a human pathogen, causing serious liver disease. At the center of the hepatitis B virus is DNA, which contains the genes the virus uses to replicate itself. Surrounding the DNA is a protein called HBcAg (hepatitis B core antigen), which cannot be detected with blood tests. Surrounding this is HBsAg, which is actually part of the protective "envelope." This envelope surrounds the virus and protects it from attack by the body's immune system. HBsAg stands for hepatitis B surface antigen and is the surface antigen of the Hepatitis-B-Virus (HBV) S-gene.

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
ALXN-1850ALXN-1850Phase 3 ClinicalAlexion Pharmaceuticals IncHypophosphatasia
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DS-1211DS-1211Phase 2 ClinicalSanford Burnham Prebys Medical Discovery Institute, Daiichi Sankyo Co LtdOssification, Heterotopic; Pseudoxanthoma Elasticum
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ALXN-1910ALXN-1910Phase 1 ClinicalAlexion Pharmaceuticals Inc
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Marketed Drug Information

English NameResearch CodeHighest Development StageCompanyEarliest Brand NameEarliest Approval CountryEarliest IndicationEarliest Approval CompanyEarliest Approval DateIndicationClinical Trial
Asfotase alfasTNALP-FcD10; ALXN-1215; sALP-FcD10; ENB-0040ApprovedAlexion Pharmaceuticals IncStrensiqJapanHypophosphatasiaAlexion Pharmaceuticals Inc2015-07-03Hypophosphatasia
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