Product Details
Synonyms
SHPS1, SIRPA, CD172A, BIT, MFR, MYD1, P84, PTPNS1
Source
Human SIRP alphaV2 Protein, His Tag (SI2-H52H9) is expressed from human 293 cells (HEK293). It contains AA Glu 31 - Arg 369 (Accession # ATD50864.1).
Predicted N-terminus: Glu 31
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 39.0 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 0.01 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
>95% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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Performance Data
SDS-PAGE

Human SIRP alphaV2 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-MALS

The purity of Human SIRP alphaV2 Protein, His Tag (Cat. No. SI2-H52H9) is more than 95% and the molecular weight of this protein is around 40-60 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA

Immobilized Human CD47, Fc Tag (HPLC-verified) (Cat. No. CD7-H5256) at 2 μg/mL (100 μL/well) can bind Human SIRP alphaV2 Protein, His Tag (Cat. No. SI2-H52H9) with a linear range of 0.078-1.25 μg/mL (QC tested).
Protocol
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Background
Recent Advances
- English Name:
Signal-regulatory protein alpha
- Category:
- Approved Drugs:
2 Details
- Drugs in Clinical Trials:
19 Details
- Highest Development Stage:
Approved



















