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Biotinylated Mouse PSCA Protein, His,Avitag™, low endotoxin (MALS verified)

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Product Number/Spec
Price
Menge
PSA-M82Ea-100ug
$710.00
PSA-M82Ea-1mg
$9010.00
PSA-M82Ea-5mg
$30075.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Synonyms

    PSCA, UNQ206, PRO232

  • Source

    Biotinylated Mouse PSCA, His,Avitag (PSA-M82Ea) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Asn 95 (Accession # P57096-1).

    Predicted N-terminus: Leu 21

    Request for sequence
  • Molecular Characterization

    PSCA Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 12.0 kDa.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SEC-MALS.

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Data Display

  • SEC-MALS

    PSCA SEC-MALS

    The purity of Biotinylated Mouse PSCA, His,Avitag (Cat. No. PSA-M82Ea) is more than 95% and the molecular weight of this protein is around 18-26 kDa verified by SEC-MALS.

    Report

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Publish Comment

Background Introduction

The Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored protein, plays an important role in tumorigenesis. The prostate stem cell antigen (PSCA) gene, which encodes a prostate-specific antigen (PSA), was identified as a gene involved in cell adhesion and proliferation. PSCA may be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.

Frontier Progress

 
Drug Development Progress
  • English Name:

    Prostate stem cell antigen

  • Category:

  • Listed Drugs Count:

    0 Details

  • Clinical Drugs Count:

    4 Details

  • Highest R&D Stage:

    Phase 1 Clinical

Drug Candidate Licensing
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