Cynomolgus LIV-1 / SLC39A6 Protein, His Tag, low endotoxin

Customer Reviews
Cat. No. / Size
Price
Qty
LV1-C52H6-100ug
$560.00
LV1-C52H6-1mg (500ug X 2)
$4285.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    SLC39A6, LIV-1, ZIP6, Zinc transporter ZIP6, ZIP-6

  • Source

    Cynomolgus LIV-1, His Tag (LV1-C52H6) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Ile 309 (Accession # XP_005586923.1).

    Predicted N-terminus: Leu 21

    Request for sequence
  • Molecular Characterization

    LIV-1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 34.5 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.05 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Customers Also Viewed

Performance Data

  • SDS-PAGE

    LIV-1 SDS-PAGE

    Cynomolgus LIV-1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • Bioactivity-ELISA

     LIV-1 ELISA

    Immobilized Cynomolgus LIV-1, His Tag (Cat. No. LV1-C52H6) at 1 μg/mL (100 μL/well) can bind Anti-LIV-1 Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).

    Protocol

Customer Reviews
Writing Reviews

Background

LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.

Recent Advances

 
Drug Development Progress
  • English Name:

    Zinc transporter ZIP6

  • Category:

  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

    2 Details

  • Highest Development Stage:

    Phase 2 Clinical

Drug Candidate Licensing
More
  • Basic Product Information
  • Product Details
  • Customers Also Viewed
  • Performance Data
  • Customer Reviews
  • Background