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Product Details
Synonyms
GUCY2C, GUC2C, STAR, STA receptor, hSTAR, GC-C
Source
Cynomolgus GUCY2C, His Tag (GUC-C52H6) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Gln 430 (Accession # XP_005570270.1).
Predicted N-terminus: Ser 24
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 48.0 kDa. The protein migrates as 65-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 0.01 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
>95% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
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Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE
Cynomolgus GUCY2C, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
SEC-MALS
The purity of Cynomolgus GUCY2C, His Tag (Cat. No. GUC-C52H6) is more than 95% and the molecular weight of this protein is around 60-80 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA
Immobilized Cynomolgus GUCY2C, His Tag (Cat. No. GUC-C52H6) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human GUCY2C Antibody, Human IgG1 with a linear range of 0.3-6 ng/mL (QC tested).
Protocol
Immobilized Monoclonal Anti-Human GUCY2C Antibody, Human IgG1 at 1 μg/mL (100 μL/well) can bind Cynomolgus GUCY2C, His Tag (Cat. No. GUC-C52H6) with a linear range of 3-25 ng/mL (Routinely tested).
Protocol
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Background
Recent Advances
Drug Development Progress- English Name：
Heat-stable enterotoxin receptor
- Category：
- Approved Drugs：
1 Details
- Drugs in Clinical Trials：
10 Details
- Highest Development Stage：
Approved
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