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Human GPR87 Full Length Protein (VLP)

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Product Number/Spec
Price
Menge
GP7-H52P3-20ug
$620.00
GP7-H52P3-100ug
$1235.00
GP7-H52P3-500ug (250ug X 2)
$4305.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Application

    1. Immunization
    2. Cell based assay (FACS or functional assay)
    3. Screening (ELISA)
  • Synonyms

    GPR87

  • Source

    Human GPR87 Full Length Protein (VLP) (GP7-H52P3) is expressed from human 293 cells (HEK293). It contains AA Gly 2 - Val 358 (Accession # Q9BY21).

    Predicted N-terminus: Asp

  • Molecular Characterization

    *The isotype control of empty/mock VLP (Cat. No. VLP-N5213) is sold separately and not included in protein, you can follow the link for product information.

    1. Structure

      Virus-like particles (VLPs) are protein particles that mimic the shape of viruses but lack a viral genome, and incorporating transmembrane proteins on the external surface.

    2. Synthesis Process

      Envelope virus-like particles (eVLPs) are produced by co-expressing target membrane proteins with viral structural proteins in mammalian cells, enabling native embedding of membrane proteins into the lipid bilayer during VLP budding. This approach preserves authentic conformation, post-translational modifications, and orientation, while creating a completely detergent-free environment with repetitive multivalent display and strong immunogenicity making them ideal for immunization, binding assays in antibody discovery and screening (ELISA), and cell-based assays such as FACS, etc.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Formulation

    The VLPs are highly immunogenic, so the immunization strategy should be optimized (antigen dose, regimen and adjuvant).

    Supplied as 0.2 μm filtered solution in PBS, Arginine, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 12 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Data Display

  • Bioactivity-ELISA

     GPR87 ELISA

    Immobilized Human GPR87 Full Length Protein (VLP) (Cat. No. GP7-H52P3) at 2 μg/mL (100 μL/well) can bind Anti-GPR87 antibody,Human IgG1 with a linear range of 2-25 ng/mL (QC tested).

    Protocol
  • Identity-DLS

     GPR87 DLS

    The mean peak Radius of VLP is 60-80 nm with more than 95% intensity as determined by dynamic light scattering (DLS).

User Reviews
Publish Comment

Background Introduction

An orphan GPCR induced by p53 and implicated in cell survival and migration. It is overexpressed in squamous cell carcinomas, pancreatic, and bladder cancers. GPR87 signaling promotes tumor cell proliferation and resistance to apoptosis, making it a potential therapeutic target for aggressive epithelial malignancies.

Frontier Progress

 
Drug Candidate Licensing
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