Product Details
Synonyms
GFR alpha like, GFR alpha-like, GFRAL, GRAL
Source
Mouse GFR alpha-like, His Tag (GFA-M52H7) is expressed from human 293 cells (HEK293). It contains AA Gln 20 - Gly 349 (Accession # Q6SJE0-1).
Predicted N-terminus: Gln 20
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 39.0 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
Customers Also Viewed
Performance Data
SDS-PAGE

Mouse GFR alpha-like, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
Bioactivity-ELISA

Immobilized Mouse GFR alpha-like, His Tag (Cat. No. GFA-M52H7) at 5 μg/mL (100 μL/well) can bind Human GDF-15, Fc Tag (Cat. No. GD5-H5269) with a linear range of 0.1-2 ng/mL (QC tested).
Protocol
Bioactivity-SPR

Mouse GFR alpha-like, His Tag (Cat. No. GFA-M52H7) immobilized on CM5 Chip can bind Mouse GDF-15, His Tag (Cat. No. GD5-M5149) with an affinity constant of 2.2 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Protocol
Customer Reviews Writing Reviews

Background
Recent Advances
- English Name:
GDNF family receptor alpha-like
- Category:
- Approved Drugs:
0 Details
- Drugs in Clinical Trials:
1 Details
- Highest Development Stage:
Phase 1 Clinical



















