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Human CD300a / LMIR1 Protein, His Tag, low endotoxin (MALS verified)

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Product Number/Spec
Price
Menge
CDA-H52H5-100ug
$380.00
CDA-H52H5-1mg (500ug X 2)
$2380.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Synonyms

    CD300A, CLM-8, CMRF-35-H9, CMRF35-H9, CMRF35-H, IRC1, IRC2, IgSF12, IRp60, CMRF35H, IGSF12, LMIR1

  • Source

    Human CD300a Protein, His Tag (CDA-H52H5) is expressed from human 293 cells (HEK293). It contains AA Leu 18 - Ser 128 (Accession # Q9UGN4-1).

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  • Molecular Characterization

    CD300a Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 14.4 kDa. The protein migrates as 16 kDa and 19-26 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Data Display

  • SDS-PAGE

    CD300a SDS-PAGE

    Human CD300a Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    CD300a SEC-MALS

    The purity of Human CD300a Protein, His Tag (Cat. No. CDA-H52H5) is more than 95% and the molecular weight of this protein is around 16-28 kDa verified by SEC-MALS.

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Publish Comment

Background Introduction

CD300a, expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.

Frontier Progress

 
Drug Development Progress
  • English Name:

    CMRF35-like molecule 8

  • Category:

  • Listed Drugs Count:

    0 Details

  • Clinical Drugs Count:

    0 Details

  • Highest R&D Stage:

    Preclinical

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