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Human CD24 Protein, Fc Tag

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Product Number/Spec
Price
Menge
CD4-H5254-100ug
$395.00
CD4-H5254-1mg
$2615.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Synonyms

    CD24, CD24A

  • Source

    Human CD24, Fc Tag (CD4-H5254) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Gly 59 (Accession # P25063-1).

    Predicted N-terminus: Ser 27

    Request for sequence
  • Molecular Characterization

    CD24 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 29.6 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Data Display

  • SDS-PAGE

    CD24 SDS-PAGE

    Human CD24, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • Bioactivity-ELISA

     CD24 ELISA

    Immobilized Human CD24, Fc Tag (Cat. No. CD4-H5254) at 10 μg/mL (100 μL/well) can bind Anti-CD24 MAb (SN3) with a linear range of 2-78 ng/mL (QC tested).

    Protocol

User Reviews
Publish Comment

  • ***e2026-02-11
    Likes
    CD24 FC protein shows great, reproducible results with fast delivery.
  • R***l2025-10-17
    Likes
    CD24 Fc protein yielded great data with soluble and plate bound format. Delivery timing of the product was very good too

Background Introduction

CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.

Frontier Progress

 
Drug Development Progress
  • English Name:

    Signal transducer CD24

  • Category:

  • Listed Drugs Count:

    0 Details

  • Clinical Drugs Count:

    7 Details

  • Highest R&D Stage:

    Phase 2 Clinical

Drug Candidate Licensing
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  • Product Details
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