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Mouse CD23 / Fc epsilon RII Protein, His Tag (MALS verified)

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Product Number/Spec
Price
Menge
CD3-M5243-100ug
$290.00
CD3-M5243-1mg
$2040.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Synonyms

    FCER2, CD23, CD23A, CLEC4J, FCE2, IGEBF, FcεRII, FcεRⅡ

  • Source

    Mouse CD23 Protein, His Tag (CD3-M5243) is expressed from human 293 cells (HEK293). It contains AA Glu 50 - Pro 331 (Accession # P20693.1).

    Predicted N-terminus: His

    Request for sequence
  • Molecular Characterization

    CD23 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 33.8 kDa. The protein migrates as 40-45 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Data Display

  • SDS-PAGE

    CD23 SDS-PAGE

    Mouse CD23 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    CD23 SEC-MALS

    The purity of Mouse CD23 Protein, His Tag (Cat. No. CD3-M5243) is more than 90% and the molecular weight of this protein is around 65-85 kDa verified by SEC-MALS.

    Report

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Publish Comment

Background Introduction

Cluster of differentiation 23 (CD23) is also known as Low affinity immunoglobulin epsilon Fc receptor (FCER2), C-type lectin domain family 4 member J (CLEC4J), Fc-epsilon-RII (FcεRII), Immunoglobulin E-binding factor (IGEBF), is the 'low-affinity' receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.

Frontier Progress

 
Drug Development Progress
  • English Name:

    Immunoglobulin epsilon Fc receptor

  • Category:

  • Listed Drugs Count:

    0 Details

  • Clinical Drugs Count:

    2 Details

  • Highest R&D Stage:

    Phase 2 Clinical

Drug Candidate Licensing
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