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Human Amyloid-like protein 2 / APLP2 Protein, His Tag, low endotoxin (MALS verified)

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Product Number/Spec
Price
Menge
AP2-H52H9-100ug
$410.00
AP2-H52H9-1mg (500ug X 2)
$3170.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Synonyms

    Amyloid beta precursor like protein 2, APLP2, APPH, CDEBP, APPL2

  • Source

    Human APLP2, His Tag (AP2-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Ser 692 (Accession # Q06481-1).

    Predicted N-terminus: Gly 32

    Request for sequence
  • Molecular Characterization

    APLP2 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 77.9 kDa. The protein migrates as 80-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Data Display

  • SDS-PAGE

    APLP2 SDS-PAGE

    Human APLP2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    APLP2 SEC-MALS

    The purity of Human APLP2, His Tag (Cat. No. AP2-H52H9) is more than 95% and the molecular weight of this protein is around 80-105 kDa verified by SEC-MALS.

    Report

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Publish Comment

Background Introduction

May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts.

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