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Product Details
Background
Recombinant Monoclonal Anti-CD45RO Antibody, Mouse (4C8) is a CD45RO primary antibody for IHC application. CD45RO (UCHL1, ubiquitin carboxyl terminal esterase L1) is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.
Product Specifications
Host SpeciesMouseIsotypeMouse IgGClone4C8ApplicationIHC-PDilution Ratio1: 200 - 1: 1000FormLiquidClonalityMonoclonalReactivityHumanSynonymsCD45ROConcentration0.9~1.1 mg/mlSpecificityReact with CD45RO protein on the membrane of target cell/tissuePurification TechProtein APreservationTris buffer, 1% BSAExperiment Protocol
Storage
Shipped at 4°C, Blue Ice. Store at +4°C for short term (1-2 weeks). Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot. The shelf life is 30 days from the date of opening.ACRO Quality Management System
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Sample Staining Data
Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S249 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
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Frontier Progress
Drug Development Progress- English Name：
Leukocyte common antigen
- Category：
- Listed Drugs Count：
0 Details
- Clinical Drugs Count：
4 Details
- Highest R&D Stage：
Phase 3 Clinical
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