ACE2

ACE2 Molekülinformation

Englischer Name	Angiotensin-converting enzyme 2	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	7	Target-Alias	Angiotensin-converting enzyme homolog，Metalloprotease MPROT15，ACEH，Angiotensin I Converting Enzyme 2，Angiotensin-converting enzyme-related carboxypeptidase，Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2，Peptidyl-Dipeptidase A，ACE-related carboxypeptidase
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Angiotensin-converting enzyme 2
Target-Alias	Angiotensin-converting enzyme homolog，Metalloprotease MPROT15，ACEH，Angiotensin I Converting Enzyme 2，Angiotensin-converting enzyme-related carboxypeptidase，Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 2，Peptidyl-Dipeptidase A，ACE-related carboxypeptidase
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	7
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

ACE2 Produktliste

Attribut
Protein (14)Beads (1)
Produktbibliothek
Online (15)
Spezies
Human (10)Rat (1)Mouse (1)Paguma larvata (1)- (1)Mink (1)
Etikett
Fc Tag & Avi Tag (1)His Tag & Avi Tag (3)His Tag (7)Fc Tag (2)- (1)Mouse IgG Fc Tag (1)
Marker
Biotin-labeled (4)Unconjugated (9)- (1)PE Labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT AC2-H5257	Human	HEK293	Human ACE2 / ACEH Protein, Fc Tag (MALS verified)	In den Warenkorb legen
HOT AC2-H52H8	Human	HEK293	Human ACE2 / ACEH Protein, His Tag (MALS verified)	In den Warenkorb legen
HOT AC2-H82E6	Human	HEK293	Biotinylated Human ACE2 / ACEH Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
AC2-H5205	Human	HEK293	Human ACE2 / ACEH Protein, Mouse IgG1 Fc Tag (MALS verified)	In den Warenkorb legen
AC2-H5255	Human	HEK293	Human ACE2 / ACEH Protein, Fc Tag (MALS verified)	In den Warenkorb legen
AC2-H52H4	Human	HEK293	Human ACE2 / ACEH Protein, His Tag (MALS verified)	In den Warenkorb legen
AC2-H82E7	Human	HEK293	Biotinylated Human ACE2 / ACEH Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
AC2-H82E8	Human	HEK293	Biotinylated Monomeric Human ACE2 / ACEH Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
AC2-H82F9	Human	HEK293	Biotinylated Human ACE2 / ACEH Protein, Fc,Avitag™	In den Warenkorb legen
AC2-HP2H3	Human	HEK293	PE-Labeled Human ACE2 / ACEH Protein, His TagStar Staining	In den Warenkorb legen

Gesamtmenge15

ACE2 Molekülhintergrund

Angiotensin-converting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 1-7. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, ACE-2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl.

ACE2 Molekülalias

ACE-2,ACEH,ACE2

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Fexlamose	MUC-031; AER-01	Phase 2 Clinical	Trinity College Dublin, University College Dublin, University Of California San Francisco	Cystic Fibrosis; Lung Diseases; Pulmonary Disease, Chronic Obstructive	Details
NKG2D-ACE2 CAR-NK cell therapy (Sidemu Biotechnology Technology)		Phase 2 Clinical	Chongqing Sidemu Biotechnology Technology Co Ltd	Coronavirus Disease 2019 (COVID-19); Hematologic Neoplasms	Details
HH-120	HH-120	Phase 2 Clinical	Huahui Health Ltd	Coronavirus Disease 2019 (COVID-19)	Details
SBK-001	SBK-001	Phase 2 Clinical	Chengdu Shibeikang Biomedical Technology Co Ltd	Acute Lung Injury; Respiratory Tract Diseases	Details
68Ga-labeled ACE2 Targeting Probe(Peking Union Medical College Hospital)	68Ga-A3	Phase 1 Clinical	Peking Union Medical College Hospital	Lung Neoplasms	Details
AOD01	AOD01; AOD-01	Phase 1 Clinical	A*Star	Coronavirus Disease 2019 (COVID-19)	Details
68Ga-DX600		Clinical	Beijing Cancer Hospital	Solid tumours	Details

Produktrezensionen

1***82022-08-06
0Menschen mögen
Human ACE2-coupled Magnetic Beads
As always, I trust ACRO’s antibody reagents! According to the technical feedback we’ve gotten, the experimental data is stable and produces good quality charts & graphs which is really helpful for us improve the experimental efficiency and advance the project.
K***k2021-10-08
1Menschen mögen
Human ACE2 / ACEH Protein, Fc Tag (MALS verified)
ACRO biosystem’s protein has been very useful in research and development for our diagnostic assays! They ship very fast and this product has been reliable so far. ACRO biosystem’s sales representative was very professional and helpful to our team! Their website and catalog is very user friendly and easy for any one to use. We always look forward to working with ACRO biosystems and their llamas!
X***n2021-09-01
12Menschen mögen
Biotinylated Human ACE2 / ACEH Protein, His,Avitag™ (MALS verified)
We have been using this antigen since early 2020. We internal QC showed very high quality, in terms of purity, solubility, sequence correctness, stability, etc. This reagent jump started our program. We have been using it in antibody screening funnel as well as blocking assays. It behaves very well in ELISA and SPR. I am also impressed by ACRO Bio's speedy logistic and technical support communications.